Spatiotemporal analysis of sheet and cloud cavitation and its damage potential

The cavitation regime has a substantial influence on the damage potential, thus it has to be considered in any specific investigation. For this purpose, we set up a test rig at the Technische Universität Darmstadt using a Circular Leading Edge hydrofoil (CLE) to analyse the damage potential of sheet and cloud cavitation. Exceeding a critical Reynolds number Re c, the cavitation regime transitions from harmless sheet cavitation to aggressive cloud cavitation. High-speed recordings of the cavitation regime are correlated with high frequency pressure data from a wall-mounted piezoelectric pressure transducer. Spatial and temporal content of the cavitating flow are captured applying proper orthogonal decomposition (POD) to the high-speed recordings. In order to determine the damage potential of the cavitation regime we apply a copper foil on the hydrofoil surface, on which plastic, crater-shaped deformations due to bubble collapses occur. Images of the surface are recorded before and after each run via two-dimensional Pit-Count microscopy. We correlate spatial modes from the cavitating flow field with the eroded surface rate from pitting tests leading to the result that cloud cavitation associated with increasing cloud size is more aggressive. A power law is identified where pitting rate increases with fourteenth power of the Reynolds number

Confinement-induced phonon softening and hardening in Sb2Te3 thin films

Scaling effects in Sesqui-chalcogenides are of major interest to understand and optimize their performance in heavily scaled applications, including topological insulators and phase-change devices. A combined experimental and theoretical study is presented for molecular beam epitaxy-grown films of antimony-telluride (Sb2Te3). Structural,vibrational, optical, and bonding properties upon varying confinement are studied for thicknesses ranging from 1.3 to 56 nm. In ultrathin films, the low-frequency coherent phonons of A(1g)(1) symmetry are softened compared to the bulk (64.5 cm(-1) at 1.3 nm compared to 68 cm(-1) at 55.8 nm). A concomitant increase of the high-frequency A(1g)(2) Raman mode is seen. X-ray diffraction analyses unravel an accompanying out of plane stretch by 5%, mainly stemming from an increase in the Te-Te gap. This conclusion is supported by density functional theory slab models, which reveal a significant dependency of chemical bonding on film thickness. Changes in atomic arrangement, vibrational frequencies, and bonding extend over a thickness range much larger than observed for other material classes. The finding of these unexpectedly pronounced thickness-dependent effects in quasi-2D material Sb2Te3 allows tuning of the film properties with thickness. The results are discussed in the context of a novel bond-type, characterized by a competition between electron localization and delocalization

Nonperturbative Evolution Equation for Quantum Gravity

A scale--dependent effective action for gravity is introduced and an exact nonperturbative evolution equation is derived which governs its renormalization group flow. It is invariant under general coordinate transformations and satisfies modified BRS Ward--Identities. The evolution equation is solved for a simple truncation of the space of actions. In 2+epsilon dimensions, nonperturbative corrections to the beta--function of Newton's constant are derived and its dependence on the cosmological constant is investigated. In 4 dimensions, Einstein gravity is found to be ``antiscreening'', i.e., Newton's constant increases at large distances.Comment: 35 pages, late

Protonation-Induced Microphase Separation in Thin Films of a Polyelectrolyte-Hydrophilic Diblock Copolymer

Block copolymers composed of poly(oligo ethylene glycol methyl ether methacrylate) and poly(2-vinylpyridine) are disordered in the neat state but can be induced to order by protonation of the P2VP block, demonstrating a tunable and responsive method for triggering assembly in thin films. Comparison of protonation with the addition of salts shows that microphase separation is due to selective protonation of the P2VP block. Increasing acid incorporation and increasing 2-vinylpyridine content for P2VP minority copolymers both promote increasingly phase-separated morphologies, consistent with protonation increasing the effective strength of segregation between the two blocks. The self-assembled nanostructures formed after casting from acidic solutions may be tuned based on the amount and type of acid incorporation as well as the annealing treatment applied after casting, where both aqueous and polar organic solvents are shown to be effective. Therefore, POEGMA-b-P2VP is a novel ion-containing block copolymer whose morphologies can be facilely tuned during casting and processing by controlling its exposure to acid.United States. Dept. of Energy. Office of Basic Energy Sciences (Award DE-SC0001088)National Science Foundation (U.S.) (Award CMMI-1246740

Roles for the Conserved Spc105p/Kre28p Complex in Kinetochore-Microtubule Binding and the Spindle Assembly Checkpoint

Kinetochores attach sister chromatids to microtubules of the mitotic spindle and orchestrate chromosome disjunction at anaphase. Although S. cerevisiae has the simplest known kinetochores, they nonetheless contain approximately 70 subunits that assemble on centromeric DNA in a hierarchical manner. Developing an accurate picture of the DNA-binding, linker and microtubule-binding layers of kinetochores, including the functions of individual proteins in these layers, is a key challenge in the field of yeast chromosome segregation. Moreover, comparison of orthologous proteins in yeast and humans promises to extend insight obtained from the study of simple fungal kinetochores to complex animal cell kinetochores.We show that S. cerevisiae Spc105p forms a heterotrimeric complex with Kre28p, the likely orthologue of the metazoan kinetochore protein Zwint-1. Through systematic analysis of interdependencies among kinetochore complexes, focused on Spc105p/Kre28p, we develop a comprehensive picture of the assembly hierarchy of budding yeast kinetochores. We find Spc105p/Kre28p to comprise the third linker complex that, along with the Ndc80 and MIND linker complexes, is responsible for bridging between centromeric heterochromatin and kinetochore MAPs and motors. Like the Ndc80 complex, Spc105p/Kre28p is also essential for kinetochore binding by components of the spindle assembly checkpoint. Moreover, these functions are conserved in human cells.Spc105p/Kre28p is the last of the core linker complexes to be analyzed in yeast and we show it to be required for kinetochore binding by a discrete subset of kMAPs (Bim1p, Bik1p, Slk19p) and motors (Cin8p, Kar3p), all of which are nonessential. Strikingly, dissociation of these proteins from kinetochores prevents bipolar attachment, even though the Ndc80 and DASH complexes, the two best-studied kMAPs, are still present. The failure of Spc105 deficient kinetochores to bind correctly to spindle microtubules and to recruit checkpoint proteins in yeast and human cells explains the observed severity of missegregation phenotypes

An agenda for rethinking mid-career master programs in public administration

The pace of societal change and the development of societal challenges have speeded up considerably during the last couple of decades, with substantial impact on different levels, i.e. ranging from global to local, or from business to government. When focusing on the public domain, these changes and challenges have had a major impact on public professionals, who face different and frequently changing questions. Mid-career programs in Public Administration (MPA) have the mission to support enrolled professionals in dealing with these changes and challenges. This article is about the development of such MPAs. Both substantive and didactic development is needed. To counter institutional inertia it seems vital to institutionalize a regular rethinking and adaptation of curricula and didactic strategies. This article identified some important points of attention and some options to deal with these in order to continuously improve the contribution of MPA programs to relevant and effective professional development and ongoing professional learning

Thermal variational principle and gauge fields

A Feynman-Jensen version of the thermal variational principle is applied to hot gauge fields, Abelian as well as non-Abelian: scalar electrodynamics (without scalar self-coupling) and the gluon plasma. The perturbatively known self-energies are shown to derive by variation from a free quadratic (''Gaussian'') trial Lagrangian. Independence of the covariant gauge fixing parameter is reached (within the order $g^3$ studied) after a reformulation of the partition function such that it depends on only even powers of the gauge field. Also static properties (Debye screening) are reproduced this way. But because of the present need to expand the variational functional, the method falls short of its potential nonperturbative power.Comment: 36 pages, LaTeX, no figures. Updated version: new title, section on static properties and some references adde