A community perspective on the role of fathers during pregnancy: a qualitative study

BACKGROUND: Defining male involvement during pregnancy is essential for the development of future research and appropriate interventions to optimize services aiming to improve birth outcomes. Study Aim: To define male involvement during pregnancy and obtain community-based recommendations for interventions to improve male involvement during pregnancy. METHODS: We conducted focus groups with mothers and fathers from the National Healthy Start Association program in order to obtain detailed descriptions of male involvement activities, benefits, barriers, and proposed solutions for increasing male involvement during pregnancy. The majority of participants were African American parents. RESULTS: The involved “male” was identified as either the biological father, or, the current male partner of the pregnant woman. Both men and women described the ideal, involved father or male partner as present, accessible, available, understanding, willing to learn about the pregnancy process and eager to provide emotional, physical and financial support to the woman carrying the child. Women emphasized a sense of “togetherness” during the pregnancy. Suggestions included creating male-targeted prenatal programs, enhancing current interventions targeting females, and increasing healthcare providers’ awareness of the importance of men’s involvement during pregnancy. CONCLUSIONS: Individual, family, community, societal and policy factors play a role in barring or diminishing the involvement of fathers during pregnancy. Future research and interventions should target these factors and their interaction in order to increase fathers’ involvement and thereby improve pregnancy outcomes

Using community-based participatory research and organizational diagnosis to characterize relationships between community leaders and academic researchers

Sustaining collaborations between community-based organization leaders and academic researchers in community-engaged research (CEnR) in the service of decreasing health inequities necessitates understanding the collaborations from an inter-organizational perspective. We assessed the perspectives of community leaders and university-based researchers conducting community-engaged research in a medium-sized city with a history of community-university tension. Our research team, included experts in CEnR and organizational theory, used qualitative methods and purposeful, snowball sampling to recruit local participants and performed key informant interviews from July 2011–May 2012. A community-based researcher interviewed 11 community leaders, a university-based researcher interviewed 12 university-based researchers. We interviewed participants until we reached thematic saturation and performed analyses using the constant comparative method. Unifying themes characterizing community leaders and university-based researchers' relationships on the inter-organizational level include: 1) Both groups described that community-engaged university-based researchers are exceptions to typical university culture; 2) Both groups described that the interpersonal skills university-based researchers need for CEnR require a change in organizational culture and training; 3) Both groups described skepticism about the sustainability of a meaningful institutional commitment to community-engaged research 4) Both groups described the historical impact on research relationships of race, power, and privilege, but only community leaders described its persistent role and relevance in research relationships. Challenges to community-academic research partnerships include researcher interpersonal skills and different perceptions of the importance of organizational history. Solutions to improve research partnerships may include transforming university culture and community-university discussions on race, power, and privilege

Advanced molecular surveillance approaches for characterization of blood borne hepatitis viruses.

Defining genetic diversity of viral infections directly from patient specimens is the ultimate goal of surveillance. Simple tools that can provide full-length sequence information on blood borne viral hepatitis viruses: hepatitis C, hepatitis B and hepatitis D viruses (HCV, HBV and HDV) remain elusive. Here, an unbiased metagenomic next generation sequencing approach (mNGS) was used for molecular characterization of HCV infections (n = 99) from Israel which yielded full-length HCV sequences in 89% of samples, with 7 partial sequences sufficient for classification. HCV genotypes were primarily 1b (68%) and 1a (19%), with minor representation of genotypes 2c (1%) and 3a (8%). HBV/HDV coinfections were characterized by suppressed HBV viral loads, resulting in sparse mNGS coverage. A probe-based enrichment approach (xGen) aiming to increase HBV and HDV coverage was validated on a panel of diverse genotypes, geography and titers. The method extended HBV genome coverage a median 61% (range 8-84%) and provided orders of magnitude boosts in reads and sequence depth for both viruses. When HBV-xGen was applied to Israeli samples, coverage was improved by 28-73% in 4 samples and identified HBV genotype A1, A2, D1 specimens and a dual B/D infection. Abundant HDV reads in mNGS libraries yielded 18/26 (69%) full genomes and 8 partial sequences, with HDV-xGen only providing minimal extension (3-11%) of what were all genotype 1 genomes. Advanced molecular approaches coupled to virus-specific capture probes promise to enhance surveillance of viral infections and aid in monitoring the spread of local subtypes

Juxtaposed sequence stratigraphy, temporal-spatial variations of sedimentation and development of modern-forming forearc Lichi Melange in North Luzon Trough forearc basin onshore and offshore eastern Taiwan: An overview

The South China Sea oceanic lithosphere has been subducting eastward beneath the Huatung Basin/Philippine Sea Plate since the Early Miocene (similar to 18 Ma). The subduction is followed by the oblique collision between the Luzon arc and the subducting Eurasian plate from 6.5 Ma. The North Luzon Trough forearc strata and the Luzon arc are then obducted northwestward as the Coastal Range, eastern Taiwan, in the last 1 Ma. The collision propagates southward and is presently active in the region offshore SE Taiwan. Integrating seismic surveys offshore and a detailed forearc stratigraphy study onshore the Coastal Range, this paper overviews the characteristics of forearc deformation, dynamic sequence stratigraphy, temporal-spatial variations of forearc sedimentation and stratigraphic correlation onshore and offshore forearc sequences in response to the oblique convergent tectonics north of 20 degrees N. Combining onshore and offshore forearc geology together allows us to reconstruct a structural evolution of the North Luzon Trough forearc basin from subduction through collision to obduction, and to discuss the mechanism and processes responsible for developments of the modern-forming forearc Lichi Melange during the active Taiwan orogeny. Seismic surveys offshore show that forearc deformation in the subduction zone is primarily caused by increase of rear prism slope and west-vergent thrusting of forearc strata along the prism top since the early forearc sedimentation. East-vergent backthrusting occurs during the late forearc sedimentation and propagates arcward when the volcanic arc collides with the accretionary prism in the collision zone. Bivergent thrusting leads to a development of the forearc Huatung Ridge popup as a bathymetric high which further controls the sedimentation of the younger forearc sequence in the collision zone. In response to the syn-sedimentation deformation, forearc depocenter shifts progressively eastward. Forearc stratigraphy thus changes from two syn-sequences bounded by an unconformity in the subduction zone to three mega-sequences juxtaposed from west to east unconformably in the collision zone. As a consequence, the forearc deformation and stratigraphy in the oblique collision zone off SE Taiwan show a characteristic temporal-spatial pattern that the lowest mega-sequence with the most intensive deformation occurs restrictedly in the west, whiles the middle and the upper mega-sequences with mild deformation crop out in the center and the eastern part of the forearc basin, respectively. Detailed biostratigraphy study using planktonic foraminifera and calcareous nannoplanktons indicates that the forearc strata onshore the Coastal Range are also composed of three sequences (lower unit S-1: 6.5-5.8 Ma; middle unit S-2: 5.8-3.0 Ma; and upper unit S-3: < 3.0-1 Ma). They were previously mapped as lithostratigraphy units of the Lichi Melange (6.5-3.0 Ma) in the west and the coherent flysch sequences of the Fanshuliao Formation (5.8-3.0 Ma) and the Paliwan Formation (< 3.0-1 Ma) the east. However, the young coherent forearc sequences in the east thrust westward ubiquitously over the old and highly deformed Lichi Melange in the west along the listric east-dipping Tuluanshan fault during the obduction. Detailed biostratigraphy study reveals that the lower sequence unit S-1 exposes restrictedly in the Lichi Melange west of the Tuluanshan fault, whereas the middle sequence unit S-2 are either mapped as part of the Lichi Melange or the coherent Fanshuliao Formation in both sides of the Tuluanshan fault, respectively. The upper sequence unit S-3 exposes exclusively east of middle sequence unit S-2 in the eastern Coastal Range. Stratigraphy and sedimentology study also reveals a temporal-spatial sedimentation variation of the upper sequence unit S-3 owing to deformation of the sequence units S-1 and S-2 together as a Pliocene Forearc Ridge at similar to 3 Ma, a scenario analog to development of the modern Huatung Ridge at similar to 1 Ma in active collision zone offshore. Temporal-spatial pattern of forearc sequences onshore the Coastal Range suggests that these three sequence units are juxtaposed from west to east and are bounded by two unconformities analog to what occur today in the collision zone offshore SE Taiwan. The characteristic deformation and an eastward-youngling trend of strata distribution onshore the Coastal Range all indicate Syn-sedimentation deformation during the oblique collision in 6.5-1 Ma. Furthermore, along the N-S orogenic strike, events of the forearc sedimentation and bivergent thrusting occur earlier onshore the obduction zone in the north than the modem collision zone offshore in the south. Across the orogenic strike forearc strata get older and deformation gets intensive from east to west onshore the Coastal Range, a scenario analog to what observed in the oblique convergent region offshore SE Taiwan. A structure reconstruction reveals that the North Luzon Trough forearc strata have experienced multiple stages of thrust deformation from subduction through collision to obduction. These deformations account for the mechanism and processes to develop the modem-forming highly sheared SSZ-bearing forearc Lichi Melange tectonically in the western Coastal Range during the last 1 Ma

Influence of the 23 October 2002 dust storm on the air quality of four Australian cities

Widespread drought and record maximum temperatures in eastern Australia produced a large dust storm on 23 October, 2002 which traversed a large proportion of eastern Australia and engulfed communities along a 2000 km stretch of coastline from south of Sydney ( NSW) to north of Mackay ( Queensland). This event provided an opportunity for a study of the impacts of rural dust upon the air quality of four Australian cities. A simple model is used to predict dust concentrations, dust deposition rates and particle size characteristics of the airborne dust in the cities. The total dust load of the plume was 3.35 to 4.85 million tones, and assuming a ( conservative) plume height of 1500 m, 62 - 90% of this dust load was deposited in-transit to the coast. It is conservatively estimated that 3.5, 12.0, 2.1 and 1.7 kilotonnes of dust were deposited during the event in Sydney, Brisbane, Gladstone and Mackay, respectively. In the South East Queensland region, this deposition is equivalent to 40% of the total annual TSP emissions for the region. The event increased TSP, PM10 and PM2.5 concentrations and reduced the visibility beyond the health and amenity guidelines in the four cities. For example, the 24-h average PM10 concentrations in Brisbane and Mackay, were 161 and 475 mu g m(-3) respectively, compared with the Australian national ambient air quality standard of 50 mu g m(-3). The 24-h average PM2.5 concentration in Brisbane was 42 mu g m(-3), compared with the national advisory standard of 25 mu g m(-3). These rural dusts significantly increased PM10/TSP ratios and decreased PM2.5/PM10 ratios, indicating that most of the particles were between PM2.5 and PM10

Phase transitions in diglyceride monolayers studied by computer simulations, pressure-area isotherms and x-ray diffraction

1,2-sn-diglyceride monolayers exhibit unique and complex phase transitions as a function of surface pressure. The dynamical response of the layer on expanding the film has been investigated by computer simulations, (π-A) isotherms and grazing-incidence X-ray diffraction. Good agreement is found between the simulations and experiments. The Langmuir film undergoes two phase transitions occurring at 38.3 and 39.8 Å2/molecule. The transition at low surface density is associated with a tilt of ≈14° in the direction close to nearest neighbour. The first transition is unique for the diglyceride molecules and has not been observed for other amphiphilic molecules. It is driven by a competition of hydrophobic/hydrophilic and intra/intermolecular forces and can be pictured as a «seesaw» mechanism. Due to the close packing of the chains at high surface pressure, the sn-1 ester group aligns with the alkyl chain, and only the sn-2 ester group is favoured to lay at the aqueous interface. Hydrophilic forces attract the sn-1 ester group, but its motion towards the aqueous subphase is hindered by intra- and intermolecular chain interactions. On expansion, the intermolecular interaction decreases, and at the first transition, the intramolecular interaction between the two chains is strong enough to cause a «swelling» of the molecules. The diffraction pattern determined in the different mesophases reveals that the layer maintains its hexagonal structure up to the second phase. Concomitant with the tilt, the structure relaxed from a hexagonal to a distorted hexagonal lattice