Women in Corneille’s \u3ci\u3eLe Cid\u3c/i\u3e and Diderot’s \u3ci\u3eLe Fils naturel\u3c/i\u3e

The role of women in literature and society has been ever evolving and has also varied between writers and even individual works. In both society and literature, women have often been either marginalized or idealized. In this essay, I will focus on the works of French writers Pierre Corneille and Denis Diderot, specifically their plays, Le Cid (The Cid, 1636) and Le Fils naturel (The Natural Son, 1757). In terms of the role of women in these two plays, there are marked differences regarding their significance as characters and their expected feminine roles as well as how they interact with the men of the plays. In Le Cid, Corneille gives his main character, Chimène, a vital role in the plot. She is a character who is treated with equity in relation to men and, interestingly, even takes on some masculine qualities in the play. However, Rosalie, Chimène’s counterpart in Diderot’s Le Fils naturel, only plays a peripheral role and is underdeveloped as a feminine presence

The MAMI Care Pathway Package: A resource to support the management of small and nutritionally at-risk infants under six months of age and their mothers (MAMI)

Globally, millions of infants under six months (u6m) are small and nutritionally at-risk, but many do not get the care they need to survive and thrive. Although the 2013 World Health Organisation (WHO) guidelines for severe malnutrition management recommend outpatient care for clinically stable infants u6m, most national guidelines still recommend inpatient care for all infants u6m. To help put the WHO recommendations into action, the MAMI Global Network has developed the MAMI Care Pathway Package – a resource to facilitate the screening, assessment, and management of small and nutritionally at-risk infants u6m and their mothers. The Package uses an integrated care pathway approach and is designed to embed within and support Integrated Management of Childhood Illness (IMCI). By improving continuity of care and facilitating patient management, the MAMI Care Pathway Package aims to help health workers improve outcomes for infants and mothers worldwide while also simplifying their care

Anatomy Academy Service-Learning Project: Attacking the Epidemic of Childhood Obesity

The World Health Organization has classified childhood obesity as one of the most serious public health concerns in the world. Obesity is known to have detrimental health consequences and be a risk for comorbidities. On top of the consequences of obesity already seen in young children at school, a lack of health education interventions in many elementary schools remains a significant health disparity. Anatomy Academy (AA) is a seven-week curriculum designed to educate children about their bodies and the importance of gaining and maintaining a healthy lifestyle. The purpose of this service-learning project was to educate elementary school students in North Las Vegas about the anatomy and physiology of the human body, nutrition, and exercise through the implementation of the AA curriculum. The elementary school students were asked to complete a pre- and post-quiz to analyze the quality of the program and the lessons\u27 resonance with students. Out of the 39 elementary students who participated in the program, 16 took both the pre- and post-quiz. The results showed that the median of the pre- and post-quiz scores were equal, with no difference between the groups (median = 7, p = 0.797). Therefore, this may suggest that the quiz may not have been challenging enough for the elementary school students and should be conducted on a larger sample size. The elementary students and staff reported to the program coordinators their satisfaction with the program. Due to the low cost of the program’s activities and the topics being outlined in the curriculum, the program is an efficient and feasible program. Coordinators are also able to develop personal and professional growth. The program allows for community educational outreach with a younger population while providing opportunities for professional development for students in medical or allied health programs

Exploration of the Southern California Borderland

E/V Nautilus cruise NA075 returned to the Southern California Continental Borderland, an area that remains largely unexplored. Part of the broader North America-Pacific plate boundary, this region extends ~300 km west of the San Andreas Fault and displays an unusually rugged physiography. During the cruise, the multibeam sonar mapped ~5,200 km2 of seafloor, and ROVs Hercules and Argus were deployed for 16 dives to explore geological and biological targets (Figure 1) and collect samples

Multi-omics analysis of severe fever with thrombocytopenia syndrome virus infection in Rhipicephalus microplus cells reveals antiviral tick factors.

Abstract The increasing prevalence of tick-borne arboviral infections worldwide necessitates advanced control strategies, particularly those targeting vectors, to mitigate the disease burden. However, the cellular interactions between arboviruses and ticks, especially for negative-strand RNA viruses, remain largely unexplored. Here, we employed a proteomics informed by transcriptomics approach to elucidate the cellular response of the Rhipicephalus microplus-derived BME/CTVM6 cell line to severe fever with thrombocytopenia syndrome virus (SFTSV) infection. We generated the first de novo transcriptomes and proteomes of SFTSV- and mock-infected tick cells, identifying key host responses and regulatory pathways. Additionally, interactome analysis of the viral nucleoprotein (N) integrated host responses with viral replication mechanisms. Finally, our dsRNA-mediated gene silencing screen revealed two novel anti-SFTSV effectors, the RNA helicases, DHX9 and UPF1. Collectively, our results provide new insights into the antiviral responses of Rhipicephalus microplus vector cells and highlight critical SFTSV restriction factors, while enriching transcriptomic and proteomic resources for future research.</p

Data-Fusion for a Vision-Aided Radiological Detection System: Sensor dependence and Source Tracking

The University of Florida is taking a multidisciplinary approach to fuse the data between 3D vision sensors and radiological sensors in hopes of creating a system capable of not only detecting the presence of a radiological threat, but also tracking it. The key to developing such a vision-aided radiological detection system, lies in the count rate being inversely dependent on the square of the distance. Presented in this paper are the results of the calibration algorithm used to predict the location of the radiological detectors based on 3D distance from the source to the detector (vision data) and the detectors count rate (radiological data). Also presented are the results of two correlation methods used to explore source tracking

Body mass index and risk of head and neck cancer in a pooled analysis of case-control studies in the International Head and Neck Cancer Epidemiology (INHANCE) Consortium

Background Head and neck cancer (HNC) risk is elevated among lean people and reduced among overweight or obese people in some studies; however, it is unknown whether these associations differ for certain subgroups or are influenced by residual confounding from the effects of alcohol and tobacco use or by other sources of biases. Methods We pooled data from 17 case-control studies including 12 716 cases and the 17 438 controls. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated for associations between body mass index (BMI) at different ages and HNC risk, adjusted for age, sex, centre, race, education, tobacco smoking and alcohol consumption. Results Adjusted ORs (95% CIs) were elevated for people with BMI at reference (date of diagnosis for cases and date of selection for controls) ≤18.5 kg/m2 (2.13, 1.75-2.58) and reduced for BMI >25.0-30.0 kg/m2 (0.52, 0.44-0.60) and BMI ≥30 kg/m2 (0.43, 0.33-0.57), compared with BMI >18.5-25.0 kg/m2. These associations did not differ by age, sex, tumour site or control source. Although the increased risk among people with BMI ≤18.5 kg/m2 was not modified by tobacco smoking or alcohol drinking, the inverse association for people with BMI > 25 kg/m2 was present only in smokers and drinkers. Conclusions In our large pooled analysis, leanness was associated with increased HNC risk regardless of smoking and drinking status, although reverse causality cannot be excluded. The reduced risk among overweight or obese people may indicate body size is a modifier of the risk associated with smoking and drinking. Further clarification may be provided by analyses of prospective cohort and mechanistic studie

Carbon-sensitive pedotransfer functions for plant available water

Currently accepted pedotransfer functions show negligible effect of management-induced changes to soil organic carbon (SOC) on plant available water holding capacity (θAWHC), while some studies show the ability to substantially increase θAWHC through management. The Soil Health Institute\u27s North America Project to Evaluate Soil Health Measurements measured water content at field capacity using intact soil cores across 124 long-term research sites that contained increases in SOC as a result of management treatments such as reduced tillage and cover cropping. Pedotransfer functions were created for volumetric water content at field capacity (θFC) and permanent wilting point (θPWP). New pedotransfer functions had predictions of θAWHC that were similarly accurate compared with Saxton and Rawls when tested on samples from the National Soil Characterization database. Further, the new pedotransfer functions showed substantial effects of soil calcareousness and SOC on θAWHC. For an increase in SOC of 10 g kg–1 (1%) in noncalcareous soils, an average increase in θAWHC of 3.0 mm 100 mm–1 soil (0.03 m3 m–3) on average across all soil texture classes was found. This SOC related increase in θAWHC is about double previous estimates. Calcareous soils had an increase in θAWHC of 1.2 mm 100 mm–1 soil associated with a 10 g kg–1 increase in SOC, across all soil texture classes. New equations can aid in quantifying benefits of soil management practices that increase SOC and can be used to model the effect of changes in management on drought resilience

Cessation of alcohol drinking, tobacco smoking and the reversal of head and neck cancer risk

Background Quitting tobacco or alcohol use has been reported to reduce the head and neck cancer risk in previous studies. However, it is unclear how many years must pass following cessation of these habits before the risk is reduced, and whether the risk ultimately declines to the level of never smokers or never drinkers. Methods We pooled individual-level data from case-control studies in the International Head and Neck Cancer Epidemiology Consortium. Data were available from 13 studies on drinking cessation (9167 cases and 12 593 controls), and from 17 studies on smoking cessation (12 040 cases and 16 884 controls). We estimated the effect of quitting smoking and drinking on the risk of head and neck cancer and its subsites, by calculating odds ratios (ORs) using logistic regression models. Results Quitting tobacco smoking for 1-4 years resulted in a head and neck cancer risk reduction [OR 0.70, confidence interval (CI) 0.61-0.81 compared with current smoking], with the risk reduction due to smoking cessation after ≥20 years (OR 0.23, CI 0.18-0.31), reaching the level of never smokers. For alcohol use, a beneficial effect on the risk of head and neck cancer was only observed after ≥20 years of quitting (OR 0.60, CI 0.40-0.89 compared with current drinking), reaching the level of never drinkers. Conclusions Our results support that cessation of tobacco smoking and cessation of alcohol drinking protect against the development of head and neck cance

Linking soil microbial community structure to potential carbon mineralization: A continental scale assessment of reduced tillage

Potential carbon mineralization (Cmin) is a commonly used indicator of soil health, with greater Cmin values interpreted as healthier soil. While Cmin values are typically greater in agricultural soils managed with minimal physical disturbance, the mechanisms driving the increases remain poorly understood. This study assessed bacterial and archaeal community structure and potential microbial drivers of Cmin in soils maintained under various degrees of physical disturbance. Potential carbon mineralization, 16S rRNA sequences, and soil characterization data were collected as part of the North American Project to Evaluate Soil Health Measurements (NAPESHM). Results showed that type of cropping system, intensity of physical disturbance, and soil pH influenced microbial sensitivity to physical disturbance. Furthermore, 28% of amplicon sequence variants (ASVs), which were important in modeling Cmin, were enriched under soils managed with minimal physical disturbance. Sequences identified as enriched under minimal disturbance and important for modeling Cmin, were linked to organisms which could produce extracellular polymeric substances and contained metabolic strategies suited for tolerating environmental stressors. Understanding how physical disturbance shapes microbial communities across climates and inherent soil properties and drives changes in Cmin provides the context necessary to evaluate management impacts on standardized measures of soil microbial activity