2,634 research outputs found

    Glacial History of the Amundsen Sea Shelf

    Get PDF
    This award, provided by the Antarctic Geology and Geophysics Program of the Office of Polar Programs, supports a marine geological investigation of the Amundsen Sea region toward a better understanding of the deglaciation history of the West Antarctic Ice Sheet (WAIS). The WAIS may be inherently unstable because it is the last marine-based ice sheet in the world. Unlike other embayments in West Antarctica, major ice streams draining into the Amundsen Sea from the interior of the WAIS lack buttressing ice shelves. Mass balance data for the distal portions of these ice streams (Pine Island and Thwaites glaciers) appear to be in balance or may be becoming negative. Because both ice streams have beds that slope downward toward the center of the ice sheet, grounding-line recession resulting from either continued thinning or sea-level rise could trigger irreversible grounding-line retreat, leading to ice-sheet disintegration and consequent global sea-level rise. The limited marine geological and geophysical data available from the Amundsen Sea suggest that grounded ice or an ice shelf occupied the inner Amundsen Sea embayment until perhaps as recently as 1000 to 2000 years ago, and this ice may have retreated rapidly in historic time.This project, a study of the marine geology and geophysics of the Amundsen Sea continental shelf from 100 degrees W to 130 degrees W, is designed to address the Amundsen Sea part of WAIS Science Plan Priority Goal H2: What is the deglaciation history in the eastern Ross, the Bellingshausen and Amundsen Seas? This project will examine bathymetric data of the Amundsen Sea continental shelf to determine the positions of former ice-steam channels, and to aid in choosing sites for sediment coring. Single-channel seismic reflection studies will be conducted in order to determine sediment-thickness patterns, to aid in choice of coring sites, and to locate and identify morphologic features indicative of former grounded ice (e.g., moraines, scours, flutes, striations, till wedges and deltas, etc.). Coring will be concentrated along former ice flow-lines. Core samples will be analyzed in the laboratory for sedimentology, to determine whether of not basal tills are present (indicating former grounded ice and its former extent), and for calcareous and siliceous microfossils. The chronology of grounding-line and ice-shelf retreat from a presumed Last Glacial Maximum position near the shelf break will be established using accelerator mass spectrometry (AMS) carbon-14 dates of acid-insoluble particulate organic carbon.This project will share ship time in the Amundsen Sea with a physical oceanographic project. Marine geologic data and samples collected will be integrated with findings of other investigators toward developing a comprehensive interpretation of the history of the WAIS

    Comprehensive analysis of lectin-glycan interactions reveals determinants of lectin specificity

    Get PDF
    Lectin-glycan interactions facilitate inter- and intracellular communication in many processes including protein trafficking, host-pathogen recognition, and tumorigenesis promotion. Specific recognition of glycans by lectins is also the basis for a wide range of applications in areas including glycobiology research, cancer screening, and antiviral therapeutics. To provide a better understanding of the determinants of lectin-glycan interaction specificity and support such applications, this study comprehensively investigates specificity-conferring features of all available lectin-glycan complex structures. Systematic characterization, comparison, and predictive modeling of a set of 221 complementary physicochemical and geometric features representing these interactions highlighted specificity-conferring features with potential mechanistic insight. Univariable comparative analyses with weighted Wilcoxon-Mann-Whitney tests revealed strong statistical associations between binding site features and specificity that are conserved across unrelated lectin binding sites. Multivariable modeling with random forests demonstrated the utility of these features for predicting the identity of bound glycans based on generalized patterns learned from non-homologous lectins. These analyses revealed global determinants of lectin specificity, such as sialic acid glycan recognition in deep, concave binding sites enriched for positively charged residues, in contrast to high mannose glycan recognition in fairly shallow but well-defined pockets enriched for non-polar residues. Focused fine specificity analysis of hemagglutinin interactions with human-like and avian-like glycans uncovered features representing both known and novel mutations related to shifts in influenza tropism from avian to human tissues. As the approach presented here relies on co-crystallized lectin-glycan pairs for studying specificity, it is limited in its inferences by the quantity, quality, and diversity of the structural data available. Regardless, the systematic characterization of lectin binding sites presented here provides a novel approach to studying lectin specificity and is a step towards confidently predicting new lectin-glycan interactions

    Geospatial Data on Parade: The Results and Implications of the GIS Analysis of Remote Sensing and Archaeological Excavation Data at Fort York’s Central Parade Ground

    Get PDF
    This article presents a case study on the application of geographical information systems (GIS) in the context of military archaeology at the Fort York National Historic Site (AjGu-26) in Toronto, Ontario. By employing GIS to amalgamate data from historic mapping, ground penetrating radar, LiDAR, and 30 years of archaeological investigation, the authors reconstruct the historic landscape at the central parade ground of this national historic site. In doing so, they identify the remains of an early 19th-century vice-regal building that served as the official residence of the lieutenant governors of Upper Canada before the American forces burned it down in 1813—an important event that later provided the justification for the British destruction of the White House. With the successful application of GIS to amalgamate multiple lines of evidence, the article serves as another case for the broader acceptance of digital data technologies into the standard methodological toolkits of archaeologists

    Geospatial Data on Parade: The Results and Implications of GIS Analysis of Remote Sensing and Archaeological Excavation Data at Fort York’s Central Parade Ground

    Get PDF
    Source at https://orb.binghamton.edu/neha/vol44/iss1/6.This article presents a case study on the application of geographical information systems (GIS) in the context of military archaeology at the Fort York National Historic Site (AjGu-26) in Toronto, Ontario. By employing GIS to amalgamate data from historic mapping, ground penetrating radar, LiDAR, and 30 years of archaeological investigation, the authors reconstruct the historic landscape at the central parade ground of this national historic site. In doing so, they identify the remains of an early 19th-century vice-regal building that served as the official residence of the lieutenant governors of Upper Canada before the American forces burned it down in 1813—an important event that later provided the justification for the British destruction of the White House. With the successful application of GIS to amalgamate multiple lines of evidence, the article serves as another case for the broader acceptance of digital data technologies into the standard methodological toolkits of archaeologists

    Impact of Velcro Cuff Closure on Forearm Skin Temperature In Surfers Wearing a 2mm and 3mm Wetsuit

    Get PDF
    International Journal of Exercise Science 13(6): 1574-1582, 2020. Surfing is a worldwide sport that often requires participants to wear a wetsuit to assist in thermoregulation. In a recent study, forearm skin temperature decreased by approximately 3 °C while wearing a wetsuit during recreational surfing. The purpose of this study was to test the hypothesis that reducing water flow in and out of the wetsuit by cuffing the wetsuit at the wrist, with a novel cuff closure system (Velcro cuff), would result in greater forearm skin temperature while surfing. One hundred and twelve (94 male, 18 female) recreational surfers between the ages of 18-50 participated in this study. Forearm skin temperature was measured at 1-minute intervals across the surf session in both arms with four wireless iButton thermal sensors located two inches from the styloid process (wrist) and olecranon process (elbow). Following instrumentation, all subjects had one of their wrists randomly cuffed with a one-inch wide Velcro cuff that was tightened to 2 cm less than the circumference of the wrist plus wetsuit. Subjects were then instructed to engage in regular recreational surfing activities for a minimum of 30 minutes at seven beaches in North San Diego County from October to April. No significant differences were found between the average cuffed wrist skin temperature and the average uncuffed wrist skin temperature (p = 0.06). However, average cuffed forearm skin temperature was significantly higher than average uncuffed forearm skin temperature (p = 0.01). Results from this study suggest that cuffing the wrist of wetsuits is a simple technique that can be utilized by surfers to significantly improve forearm skin temperature during surfing. These findings may also have an implication on future wetsuit designs

    Characterization of Adult Heart Rate Responses During Recreational Skateboarding at Community Skateparks

    Get PDF
    International Journal of Exercise Science 13(2): 501-510, 2020. Youth participating in recreational skating at community skate parks attain exercise intensities and durations that are comparable with the CDC’s exercise recommendations for cardiovascular fitness for their age group. However, it is currently unclear if adults who skateboard in the same environment also achieve the recommended intensities and durations for cardiovascular fitness. Therefore, the purpose of this study was to test the hypothesis that skateboarding would elicit heart rates and durations consistent with the CDC’s recommendations for cardiovascular fitness in adults. Fifty-five subjects between ages 18-55 were recruited from six community skateparks for this study. Subjects completed a questionnaire and were instrumented with a Polar V800 heart rate receiver on the left wrist and an H7 Bluetooth heart rate transmitter around the chest below the pectoralis major. Participants were instructed to engage in a typical skateboarding session on their own board with the duration and intensity of activity to be determined by the participant. The mean age of the participants was 27.4 ± 8.5 years, and participants reported skateboarding at a community skate park a mean of 3.1 ± 1.8 days/week. Participants had a mean heart rate of 138.2 ± 21.9 beats per minute (71.7% of age predicted maximum), skated for 65.5 ± 36.2 minutes, and traveled 4.56 ± 4.5 kilometers. Subjects spent 70% of their total duration at moderate-intensity or above and 30% within the low, and below low-intensity range. Results from this study suggest that adults participating in recreational skateboarding in community skateparks achieve the CDC’s exercise recommendations for cardiovascular fitness. These findings may have implications for community skatepark design and professional training programs for adult skateboarding athletes

    Coastal Training Market Analysis: Final Report

    Get PDF
    A market is emerging for policy makers in the area of coastal resources management. Individuals, as professionals or private citizens, are frequently called upon to make decisions regarding coastal environmental issues. The context in which they do so varies considerably; thus education and training in this topic area serves to heighten and expand the knowledge base of the coastal decision-maker

    Coastal Training Market Analysis: Final Report

    Get PDF
    A market is emerging for policy makers in the area of coastal resources management. Individuals, as professionals or private citizens, are frequently called upon to make decisions regarding coastal environmental issues. The context in which they do so varies considerably; thus education and training in this topic area serves to heighten and expand the knowledge base of the coastal decision-maker

    VETA-1 x ray detection system

    Get PDF
    The alignment and X-ray imaging performance of the Advanced X-ray Astrophysics Facility (AXAF) Verification Engineering Test Article-I (VETA-I) was measured by the VETA-I X-Ray Detection System (VXDS). The VXDS was based on the X-ray detection system utilized in the AXAF Technology Mirror Assembly (TMA) program, upgraded to meet the more stringent requirements of the VETA-I test program. The VXDS includes two types of X-ray detectors: (1) a High Resolution Imager (HRI) which provides X-ray imaging capabilities, and (2) sealed and flow proportional counters which, in conjunction with apertures of various types and precision translation stages, provide the most accurate measurement of VETA-I performance. Herein we give an overview of the VXDS hardware including X-ray detectors, translation stages, apertures, proportional counters and flow counter gas supply system and associated electronics. We also describe the installation of the VXDS into the Marshall Space Flight Center (MSFC) X-Ray Calibration Facility (XRCF). We discuss in detail the design and performance of those elements of the VXDS which have not been discussed elsewhere; translation systems, flow counter gas supply system, apertures and thermal monitoring system
    • …
    corecore