1,015 research outputs found

    The Indivisibility of Economic and Political Rights

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    A review of: Development as Freedom by Amartya Sen. New York: Knopf , 1999 (Paperback Edition: Random House, 2000). 366pp

    The American Rejection of Economic Rights as Human Rights and the Declaration of Independence: Does the Pursuit of Happiness Require Basic Economic Rights?

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    This article explores the economic dimension of the Pursuit of Happiness in the Declaration of Independence and how it undercuts the notion that economic and social rights under international human rights law are somehow un-American. The United States government seems to believe that economic rights are not truly human rights, but rather radical Cold War era entitlements advocated by communists. The minimum-needs conception of the pursuit of happiness suggests that economic rights are enshrined in a document considered part of the foundation of democracy. Part I evaluates the rejection of economic rights in the United States, focusing on international commitments. Part II turns to the Declaration of Independence, specifically, the Pursuit of Happiness. Drawing on eighteenth-century political thought, it asserts that the pursuit of happiness establishes an inalienable right that includes an economic dimension. Part III argues that the right to pursue happiness entails a concomitant governmental duty: the duty to facilitate the pursuit of happiness by providing minimum economic means. Although the Declaration of Independence has not been interpreted as legally enforceable, the principles of the Declaration form the basis for the government and must be followed by it. The article shows how this obligation to ensure basic economic rights is also contained in various international instruments. Far from being foreign to American political thought, this duty is provided for and must be fulfilled under the principles of the Declaration of Independence

    Comparing the Interests of Justice : What the International Criminal Court Can Learn from New York Law

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    This article addresses the debate over whether the Prosecutor of the International Criminal Court should adopt ex ante guidelines for prosecutorial discretion in order to increase transparency and legitimacy. It focuses on one of the most ambiguous provisions of the Rome Statute: allowing the Prosecutor to decline to prosecute in the “interests of justice.” Specifically, this article will examine the experience of New York in operationalizing a domestic statutory analogue to the Rome Statute provision: dismissal of cases “in furtherance of justice.” An analysis of New York law yields three core lessons that carry over to the international sphere despite differences in the systems. First, a requirement of a written rationale regarding the exercise of discretion does not necessarily yield thorough or convincing explanations. This undermines arguments that the legitimacy of the International Criminal Court will be enhanced by public explanations of prosecutorial discretion. Second, such explanations may backfire when the balancing of nebulous factors leads to apparently inconsistent or arbitrary reasoning and results, which may undercut the credibility of the decision-maker. Finally, the lack of a guiding theory to drive the interpretation of ambiguous criteria can lead to more confusion than clarity when there is no agreement on the theoretical justifications for prosecution, as seen in both the domestic and international systems. The experience of New York, therefore, supports skepticism of the efficacy of ex ante criteria for the exercise of discretion, particularly for complex decisions regarding the interests of justice. If such criteria are nonetheless adopted, the New York experience offers suggestions on crafting a more effective approach

    The Impact of States Parties' Reservations to the Convention on the Elimination of All Forms of Discrimination Against Women

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    Article published in the Michigan State Law Review

    Rapid neuronal differentiation of induced pluripotent stem cells for measuring network activity on micro-electrode arrays

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    Neurons derived from human induced Pluripotent Stem Cells (hiPSCs) provide a promising new tool for studying neurological disorders. In the past decade, many protocols for differentiating hiPSCs into neurons have been developed. However, these protocols are often slow with high variability, low reproducibility, and low efficiency. In addition, the neurons obtained with these protocols are often immature and lack adequate functional activity both at the single-cell and network levels unless the neurons are cultured for several months. Partially due to these limitations, the functional properties of hiPSC-derived neuronal networks are still not well characterized. Here, we adapt a recently published protocol that describes production of human neurons from hiPSCs by forced expression of the transcription factor neurogenin-212. This protocol is rapid (yielding mature neurons within 3 weeks) and efficient, with nearly 100% conversion efficiency of transduced cells (>95% of DAPI-positive cells are MAP2 positive). Furthermore, the protocol yields a homogeneous population of excitatory neurons that would allow the investigation of cell-type specific contributions to neurological disorders. We modified the original protocol by generating stably transduced hiPSC cells, giving us explicit control over the total number of neurons. These cells are then used to generate hiPSC-derived neuronal networks on micro-electrode arrays. In this way, the spontaneous electrophysiological activity of hiPSC-derived neuronal networks can be measured and characterized, while retaining interexperimental consistency in terms of cell density. The presented protocol is broadly applicable, especially for mechanistic and pharmacological studies on human neuronal networks

    ウィスコンシン ダイガク マディソンコウ ガ ジッシ シテイル ナンキョク ムジン キショウ カンソク (AWS) ケイカク ノ 2011-2012 ネン カキ ノ カツドウ

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    ウィスコンシン大学マディソン校で推進している南極無人気象観測計画(Antarctic Automatic Weather Station(AWS)program)の32 年目の観測が,2011/2012年の南半球夏期に完了した.無人気象観測網を利用して南極の気象と気候の研究が行われている.今シーズンはロス島周辺域,ロス棚氷,西南極,東南極にわたる領域で活動した.基本的に観測点のデータはアルゴス衛星を中継して配信されるが,今年はロス島周辺域の多くの観測点で,マクマード基地を中継して"Freewave modem"を通して配信された.各無人気象観測点報告には,現在設置されている測器と動作状況が含まれる.また,無人気象観測計画の全体像を,野外活動の実施状況に沿って示す.During the 2011-2012 austral summer, the Antarctic Automatic Weather Station (AWS) program at the University of Wisconsin?Madison completed its 32nd year of observations. Ongoing studies utilizing the network include topics in Antarctic meteorology and climate studies. This field season consisted of work throughout the Ross Island area, the Ross Ice Shelf, West Antarctica, and East Antarctica. Argos satellite transmissions are the primary method for relaying station data, but throughout this year, a number of stations in the Ross Island area have been converted to Freewave modems, with their data being relayed through McMurdo station. Each AWS station report contains information regarding the instrumentation currently installed and the work performed at each site. An overview of the AWS applications is included along with field work accomplished

    Automatic Weather Station (AWS) Program operated by the University of Wisconsin-Madison during the 2012-2013 field season: Challenges and Successes

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    ウィスコンシン大学マディソン校で推進している南極無人気象観測計画(Antarctic Automatic Weather Station(AWS)program)の,2012-2013年のフィールド調査および結果の概要を報告する.今期はAWS 観測網の歴史上,特異なシーズンであった.ロス島地域が温暖であったことは氷上滑走路の利用に影響を及ぼし,いくつかの設営面での制約に直面した. 柔軟な計画により,限られた条件下でAWS サービルを最大化し,自動観測ネットワークへの要求に対応する最善の手段をとることができた.This report reviews 2012-2013 field season activities of the University of Wisconsin-Madison's Antarctic Automatic Weather Station (AWS) program, summarizes the science that these sites are supporting, and outlines the factors that impact the number of AWS sites serviced in any given field season. The 2012-2013 austral summer season was unusual in the AWS network history. Challenges encountered include, but are not limited to, warmer than normal conditions in the Ross Island area impacting airfield operations, changes to logistical procedures, and competition for shared resources. A flexible work plan provides the best means for taking on these challenges while maximizing AWS servicing efforts under restricted conditions and meeting the need for routine servicing that maintaining an autonomous observing network demands
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