7,066 research outputs found

    Modifications on nucleon parameters at finite temperature

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    Taking into account the additional operators coming up at finite temperature, we investigate the mass and residue of the nucleon in the framework of thermal QCD sum rules. We observe that the mass and residue of the nucleon are initially insusceptible to increase of temperature, however after a certain temperature, they start to fall increasing the temperature.Comment: 12 Pages, 4 Figures and 1 Tabl

    Thermal behavior of the mass and residue of hyperons

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    We investigate the mass and residue of the Σ\Sigma, Λ\Lambda and Ξ\Xi hyperons at finite temperature in the framework of thermal QCD sum rules. In our calculation, we take into account the additional operators coming up at finite temperature. We find the temperature-dependent continuum threshold for each hyperon using the obtained sum rules for their mass and residue. The numerical results demonstrate that the mass and residue of the particles under consideration remain stable up to a certain temperature, after which they decrease by increasing the temperature.Comment: 25Pages, 6 Figures and 2 Table

    Thermal QCD Sum Rules Study of Vector Charmonium and Bottomonium States

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    We calculate the masses and leptonic decay constants of the heavy vector quarkonia, J/ψJ/\psi and Υ\Upsilon mesons at finite temperature. In particular, considering the thermal spectral density as well as additional operators coming up at finite temperature, the thermal QCD sum rules are acquired. Our numerical calculations demonstrate that the masses and decay constants are insensitive to the variation of temperature up to T100 MeVT\cong 100 ~MeV, however after this point, they start to fall altering the temperature. At deconfinement temperature, the decay constants attain roughly to 45% of their vacuum values, while the masses are diminished about 12%, and 2.5% for J/ψJ/\psi and Υ\Upsilon states, respectively. The obtained results at zero temperature are in good consistency with the existing experimental data as well as predictions of the other nonperturbative models. Considerable decreasing in the values of the decay constants can be considered as a sign of the quark gluon plasma phase transition.Comment: 14 Pages, 8 Figures and 2 Table

    Synergistic Effect of Hyaluronate Fragments in Retinaldehyde-Induced Skin Hyperplasia Which Is a Cd44-Dependent Phenomenon

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    BACKGROUND: CD44 is a polymorphic proteoglycan and functions as the principal cell-surface receptor for hyaluronate (HA). Heparin-binding epidermal growth factor (HB-EGF) activation of keratinocyte erbB receptors has been proposed to mediate retinoid-induced epidermal hyperplasia. We have recently shown that intermediate size HA fragments (HAFi) reverse skin atrophy by a CD44-dependent mechanism. METHODOLOGY AND PRINCIPAL FINDINGS: Treatment of primary mouse keratinocyte cultures with retinaldehyde (RAL) resulted in the most significant increase in keratinocyte proliferation when compared with other retinoids, retinoic acid, retinol or retinoyl palmitate. RAL and HAFi showed a more significant increase in keratinocyte proliferation than RAL or HAFi alone. No proliferation with RAL was observed in CD44-/- keratinocytes. HA synthesis inhibitor, 4-methylumbelliferone inhibited the proliferative effect of RAL. HB-EGF, erbB1, and tissue inhibitor of MMP-3 blocking antibodies abrogated the RAL- or RAL- and HAFi-induced keratinocyte proliferation. Topical application of RAL or RAL and HAFi for 3 days caused a significant epidermal hyperplasia in the back skin of wild-type mice but not in CD44-/- mice. Topical RAL and HAFi increased epidermal CD44 expression, and the epidermal and dermal HA. RAL induced the expression of active HB-EGF and erbB1. However, treatment with RAL and HAFi showed a more significant increase in pro-HB-EGF when compared to RAL or HAFi treatments alone. We then topically applied RAL and HAFi twice a day to the forearm skin of elderly dermatoporosis patients. After 1 month of treatment, we observed a significant clinical improvement. CONCLUSIONS AND SIGNIFICANCE: Our results indicate that (i) RAL-induced in vitro and in vivo keratinocyte proliferation is a CD44-dependent phenomenon and requires the presence of HA, HB-EGF, erbB1 and MMPs, (ii) RAL and HAFi show a synergy in vitro and in vivo in mouse skin, and (iii) the combination of RAL and HAFi seems to have an important therapeutic effect in dermatoporosis

    A study of the Zygaenidae (Lepidoptera) fauna of Central Anatolia, Turkey

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    The Zygaenidae fauna in some provinces (Aksaray, Karaman, Kayseri, Konya, Nevşehir and Niğde) of Central Anatolia was studied using attractant traps as well as by netting specimens in biotopes in 2017. The sex attractants for the Procridinae had been produced in the Crimean Federal University and were esters of 2 dodecenoic acid and isomers of 2-butanol: EFETOV-2 [racemic mixture of R- and S-enantiomers], EFETOV-S-2 [R-enantiomer] and EFETOV-S-S-2 [S-enantiomer]. Zygaena attractants were made at Canterbury Christ Church University using a range of acetate compounds with known attraction to various genera as originally identified by Priesner et al. (1984). Fourteen Zygaenidae species from four genera belonging to Procridinae and Zygaeninae subfamilies were found: Rhagades Wallengren, 1863 (1 species), Adscita Retzius, 1783 (1 species), Jordanita Verity, 1946 (4 species), and Zygaena Fabricius, 1775 (8 species)

    mESAdb: microRNA expression and sequence analysis database

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    Cataloged from PDF version of article.microRNA expression and sequence analysis database (http://konulab.fen.bilkent.edu.tr/mirna/) (mESAdb) is a regularly updated database for the multivariate analysis of sequences and expression of microRNAs from multiple taxa. mESAdb is modular and has a user interface implemented in PHP and JavaScript and coupled with statistical analysis and visualization packages written for the R language. The database primarily comprises mature microRNA sequences and their target data, along with selected human, mouse and zebrafish expression data sets. mESAdb analysis modules allow (i) mining of microRNA expression data sets for subsets of microRNAs selected manually or by motif; (ii) pair-wise multivariate analysis of expression data sets within and between taxa; and (iii) association of microRNA subsets with annotation databases, HUGE Navigator, KEGG and GO. The use of existing and customized R packages facilitates future addition of data sets and analysis tools. Furthermore, the ability to upload and analyze user-specified data sets makes mESAdb an interactive and expandable analysis tool for microRNA sequence and expression data

    5-Hydroxymethylcytosine Loss in Conjunctival Melanoma.

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    Conjunctival and cutaneous melanoma partially share similar clinical and molecular backgrounds. As 5-hydroxymethylcytosine (5-hmC) loss has been demonstrated in cutaneous melanoma, we decided to assess if similar changes were occurring in conjunctival melanoma. 5-methylcytosine (5-mC), 5-hmC and TET2 were respectively identified by immunohistochemistry and RNA ISH in 40 conjunctival nevi and 37 conjunctival melanomas. Clinicopathological correlations were established. 5-mC, TET2 and 5-hmC were respectively identified in 67.5%, 95% and 100% of conjunctival nevi and in 81.1%, 35.1% and 54% of conjunctival melanomas. A significant 5-hmC and TET2 loss was identified in conjunctival melanoma comparing to nevus, as well as a significant correlation between TET2 and 5-hmC expression. In the melanomas, 5-hmC expression was only significantly associated with local lymphatic invasion, but not with other clinicopathological parameters. There was a correlation between TET2 expression and the localization of the tumors. 5-mC expression was not associated with any clinicopathological parameters. We identified a significant 5-hmC loss in conjunctival melanoma similar to cutaneous melanoma. This loss may possibly be attributed to TET2 loss or IDH1 mutations. 5-hmC loss in conjunctival melanoma may help in the differential diagnosis between atypical conjunctival nevus and conjunctival melanoma

    Hydrodynamic Equation for the Breakdown of the Quantum Hall Effect in a Uniform Current

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    The hydrodynamic equation for the spatial and temporal evolution of the electron temperature T_e in the breakdown of the quantum Hall effect at even-integer filling factors in a uniform current density j is derived from the Boltzmann-type equation, which takes into account electron-electron and electron-phonon scatterings. The derived equation has a drift term, which is proportional to j and to the first spatial derivative of T_e. Applied to the spatial evolution of T_e in a sample with an abrupt change of the width along the current direction, the equation gives a distinct dependence on the current direction as well as a critical relaxation, in agreement with the recent experiments.Comment: 4 pages, 1 Postscript figure, corrected equations, to be published in J. Phys. Soc. Jpn. 70 (2001) No.
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