NOVA INFORMACIJSKA TEHNOLOGIJA PROCJENE KORISTI IZDVAJANJA CESTA POMOĆU SATELITSKIH SNIMKI VISOKE REZOLUCIJE TEMELJENE NA PCNN I C-V MODELU

Road extraction from high resolution satellite images has been an important research topic for analysis of urban areas. In this paper road extraction based on PCNN and Chan-Vese active contour model are compared. It is difficult and computationally expensive to extract roads from the original image due to presences of other road-like features with straight edges. The image is pre-processed using median filter to reduce the noise. Then road extraction is performed using PCNN and Chan-Vese active contour model. Nonlinear segments are removed using morphological operations. Finally the accuracy for the road extracted images is evaluated based on quality measures.Izdvajanje cesta pomoću satelitskih slika visoke rezolucije je važna istraživačka tema za analizu urbanih područja. U ovom radu ekstrakcije ceste se uspoređuju na PCNN i Chan-Vese aktivnom modelu. Teško je i računalno skupo izdvojiti ceste iz originalne slike zbog prisutnosti drugih elemenata ravnih rubova sličnih cestama. Slika je prethodno obrađena korištenjem filtera za smanjenje smetnji. Zatim se ekstrakcija ceste izvodi pomoću PCNN i Chan-Vese aktivnog modela konture. Nelinearni segmenti su uklonjeni primjenom morfoloških operacija. Konačno, točnost za ceste izdvojene iz slika se ocjenjuje na temelju kvalitativnih mjera

A small oxazine compound as an anti-tumor agent: A novel pyranoside mimetic that binds to VEGF, HB-EGF, and TNF-α

A novel pyranoside mimetic compound, DMBO (2-(2,6-difluorophenyl)-5-(4-methoxyphenyl)-1-oxa-3-azaspiro5.5undecane), was designed and synthesized. The sugar mimicking behavior of DMBO was addressed by its ability to bind several growth factors/cytokines such as vascular endothelial growth factor (VEGF), heparin-binding epidermal growth factor-like growth factor (HB-EGF), and tumor necrosis factor (TNF)-α as demonstrated by the recently developed surface plasmon resonance assay. DMBO exhibited strong anti-proliferation activity in vitro against tumor cells including a highly metastatic murine osteosarcoma cell line LM8G7 that secretes VEGF as well as two human ovarian cell lines, OVSAHO and SKOV-3, which secrete TNF-α and HB-EGF respectively. Furthermore, DMBO inhibited the metastatic activity to the mouse liver of LM8G7 cells injected from a lateral tail vein, and affected the heparan-degrading activity of LM8G7 cells. Here, we report that DMBO acts as a human heparanase inhibitor in vitro possibly as a substrate mimetic. DMBO also inhibited the migration and invasion of LM8G7 cells and angiogenic events such as endothelial cell proliferation, migration and capillary tube-like formation in vitro. More prominently, the administration of DMBO with heparin resulted in synergistic anti-tumor effects in mouse model. of. osteosarcoma. These preclinical data shows the potential anti-cancer effects of DMBO. © 2010 Elsevier Ireland Ltd

Screening of Indigenous Oxalate Degrading Lactic Acid Bacteria from Human Faeces and South Indian Fermented Foods: Assessment of Probiotic Potential

Lactic acid bacteria (LAB) have the potential to degrade intestinal oxalate and this is increasingly being studied as a promising probiotic solution to manage kidney stone disease. In this study, oxalate degrading LAB were isolated from human faeces and south Indian fermented foods, subsequently assessed for potential probiotic property in vitro and in vivo. Based on preliminary characteristics, 251 out of 673 bacterial isolates were identified as LAB. A total of 17 strains were found to degrade oxalate significantly between 40.38% and 62.90% and were subjected to acid and bile tolerance test. Among them, nine strains exhibited considerable tolerance up to pH 3.0 and at 0.3% bile. These were identified as Lactobacillus fermentum and Lactobacillus salivarius using 16S rDNA sequencing. Three strains, Lactobacillus fermentum TY5, Lactobacillus fermentum AB1, and Lactobacillus salivarius AB11, exhibited good adhesion to HT-29 cells and strong antimicrobial activity. They also conferred resistance to kanamycin, rifampicin, and ampicillin, but were sensitive to chloramphenicol and erythromycin. The faecal recovery rate of these strains was observed as 15.16% (TY5), 6.71% (AB1), and 9.3% (AB11) which indicates the colonization ability. In conclusion, three efficient oxalate degrading LAB were identified and their safety assessments suggest that they may serve as good probiotic candidates for preventing hyperoxaluria

Antidiabetic Activity and Molecular Docking Analysis of Milky Mushroom (Calocybe indica) Grown on the Renewable Substrate

As part of the circular economy idea, rice straw without additives has been investigated as a way to turn agricultural waste into products with added value. The nutrients in the substrate, Calocybe indica yield, and biological effects were all calculated. In this investigation, the methanol extract was used. GCMS was examined to discover the necessary compounds present in fungi. A surplus of mushrooms was harvested, and it was discovered that the growth of mushrooms on the rice substrate took place in less than five days. At a humidity of 93%, biological efficiency was determined to be in the range of 54.5-130.9%. In vitro and molecular docking results for the antidiabetic showed good inhibitory properties. As a result, rice straw could be a productive and affordable growing medium for milky mushrooms

The PI3K/Akt/mTOR axis in head and neck cancer: functions, aberrations, cross‐talk, and therapies

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/113753/1/odi12206.pd

Research output performance of Dyscalculia (2011–2020): A Bibliometric Analysis

This research paper presents a Bibliometric analysis on Dyscalculia research publications published during 2011-2020 in Web of Science. The result has pointed out the merits and weaknesses of the journal which can be helpful for its further development. Total publications during the study period (2011-2020) were 560 articles on dyscalculia, distributed in 12 document types and eight languages, published by 1406 authors with 14768 cited references 591 organizations, and 51 countries. The 560 articles are scattered in 226 journals in which Journal of Frontiers in Psychology (49), was the most published and ranked first (IF2020 =2.067). This study determines that there are many top papers originated from journals with the highest Impact Factor and higher rank in the Web of Science category. The result reveals that the publications are not fit into Bradford’s law of scatterings

Evaluation of Conductivity Measurement Methods for Conductive Particulate Polymer Composite

SIP-FRP-01 project aims at the development of conductive polymer composites for Electromagnetic interference shielding (EMI) applications. Highly conductive materials are best suited for electromagnetic shielding. Polymers are generally insulators in nature