144 research outputs found

    Review of \u3ci\u3eRich Indians: Native People and the Problem of Wealth in American History\u3c/i\u3e by Alexandra Harmon

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    Across American history, Native American tribes were impoverished through land and natural resource appropriations accomplished through a wide variety of well-documented political, military, and cultural means. Alexandra Harmon, in her book, provocatively titled Rich Indians, focuses on a handful of exceptions to this statistical pattern to explore American discourses about wealth accumulation by Native Americans. Armed with an impressive collection of primary sources, as well as literature from history and anthropology, Harmon also uncovers parallel discourses by Native Americans themselves about wealth accumulation among their own peoples. The result is a complex, multilayered, and fascinating melange of contradictory attitudes and beliefs that simultaneously promote and disparage the efforts of these rich Indians

    Interviews with Charley King, Barbara Hall Maricle, Vern Kear, Sherry Smith, Elizabeth Stoskopt, Martha Margheim, Verna Schneider, Edith M. Hill, Master John Sackett, Rose Arnold, Olga Elizabeth Luschen Dennis, and Clarence Loredstsch

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    Interviews with Charley King, Barbara Hall Maricle, Vern Kear, Sherry Smith, Elizabeth Stoskopt, Martha Margheim, Verna Schneider, Edith M. Hill, Master John Sackett, Rose Arnold, Olga Elizabeth Luschen Dennis, and Clarence Loredstsch The first tape is missing. Content begins with the partial interview of Olga Elizabeth Luschen Dennis. 00:00:00 - Family in Russell County (partial) 00:01:02 - Meeting her husband for the first time 00:02:32 - Girlhood experiences and reminiscences 00:03:50 - Pre-recorded History of Fort Larned 00:07:04 - Unknown speaker, Kit Carson\u27s killing of a mule he mistook for an Indigenous American 00:10:46 - Buffalo Bill Cody 00:13:03 - Stories about the Kiowa 00:16:06 - Woodland Tribe in Pawnee County, KS 00:18:24 - Quivira Tribe in Pawnee County, KS 00:21:46 - Exhuming Indigenous remains in 1958 00:23:16 - Woodland Tribe pottery 00:27:32 - Dog skeleton 00:33:57 - Woodland Tribe weapons 00:35:42 - Woodland Tribe ornamentation 00:39:05 - Introduction to interview with Clarence Loredstsch by Louise Maxwell. This portion of the recording is muffled and difficult to understand. 00:39:43 - Fort Fletcher 00:45:30 - Graves and landmarkshttps://scholars.fhsu.edu/sackett/1054/thumbnail.jp

    Some , And Possibly All, Scalar Inferences Are Not Delayed: Evidence For Immediate Pragmatic Enrichment

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    Scalar inferences are commonly generated when a speaker uses a weaker expression rather than a stronger alternative, e.g., John ate some of the apples implies that he did not eat them all. This article describes a visual-world study investigating how and when perceivers compute these inferences. Participants followed spoken instructions containing the scalar quantifier some directing them to interact with one of several referential targets (e.g., Click on the girl who has some of the balloons). Participants fixated on the target compatible with the implicated meaning of some and avoided a competitor compatible with the literal meaning prior to a disambiguating noun. Further, convergence on the target was as fast for some as for the non-scalar quantifiers none and all. These findings indicate that the scalar inference is computed immediately and is not delayed relative to the literal interpretation of some. It is argued that previous demonstrations that scalar inferences increase processing time are not necessarily due to delays in generating the inference itself, but rather arise because integrating the interpretation of the inference with relevant information in the context may require additional time. With sufficient contextual support, processing delays disappear

    Clinical outcomes of patients with corticosteroid refractory immune checkpoint inhibitor induced enterocolitis treated with infliximab

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    Introduction Immune Checkpoint Inhibitors (CPI) have changed the treatment landscape for many cancers, but also cause severe inflammatory side effects including enterocolitis. CPI-induced enterocolitis is treated empirically with corticosteroids, and infliximab (IFX) is used in corticosteroid-refractory cases. However, robust outcome data for these patients are scarce. Methods We conducted a multi-centre (six cancer centres), cohort study of outcomes in patients treated with IFX for corticosteroid-refractory CPI-induced enterocolitis between 2007 and 2020. The primary outcome was corticosteroid-free clinical remission (CFCR) with CTCAE grade 0 for diarrhoea at 12 weeks after IFX initiation. We also assessed cancer outcomes at one year using RECIST criteria. Results 127 patients (73 male; median age 59 years) were treated with IFX for corticosteroid-refractory CPI-induced enterocolitis. Ninety-six (75.6%) patients had diarrhoea CTCAE grade >2 and 115 (90.6%) required hospitalisation for colitis. CFCR was 41.2% at 12 weeks and 50.9% at 26 weeks. In multivariable logistical regression, IFX-resistant enterocolitis was associated with rectal bleeding (OR 0.19; 95% CI 0.04-0.80; p=0.03) and absence of colonic crypt abscesses (OR 2.16; 95% CI 1.13-8.05; p=0.03). Cancer non-progression was significantly more common in patients with IFX-resistant enterocolitis (64.4%) as compared to patients with IFX-responsive enterocolitis (37.5%; p=0.013). Conclusion This is the largest study to date reporting outcomes of IFX therapy in patients with corticosteroid-refractory CPI-induced enterocolitis. Utilizing pre-defined robust endpoints, we have demonstrated that fewer than half of patients achieved CFCR. Our data also indicate that cancer outcomes may be better in patients developing prolonged and severe inflammatory side effects of CPI-therapy

    Acute kidney disease and renal recovery : consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup

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    Consensus definitions have been reached for both acute kidney injury (AKI) and chronic kidney disease (CKD) and these definitions are now routinely used in research and clinical practice. The KDIGO guideline defines AKI as an abrupt decrease in kidney function occurring over 7 days or less, whereas CKD is defined by the persistence of kidney disease for a period of > 90 days. AKI and CKD are increasingly recognized as related entities and in some instances probably represent a continuum of the disease process. For patients in whom pathophysiologic processes are ongoing, the term acute kidney disease (AKD) has been proposed to define the course of disease after AKI; however, definitions of AKD and strategies for the management of patients with AKD are not currently available. In this consensus statement, the Acute Disease Quality Initiative (ADQI) proposes definitions, staging criteria for AKD, and strategies for the management of affected patients. We also make recommendations for areas of future research, which aim to improve understanding of the underlying processes and improve outcomes for patients with AKD

    The atlas of StW 573 and the late emergence of human-like head mobility and brain metabolism

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    Functional morphology of the atlas reflects multiple aspects of an organism’s biology. More specifically, its shape indicates patterns of head mobility, while the size of its vascular foramina reflects blood flow to the brain. Anatomy and function of the early hominin atlas, and thus, its evolutionary history, are poorly documented because of a paucity of fossilized material. Meticulous excavation, cleaning and high-resolution micro-CT scanning of the StW 573 (‘Little Foot’) skull has revealed the most complete early hominin atlas yet found, having been cemented by breccia in its displaced and flipped over position on the cranial base anterolateral to the foramen magnum. Description and landmark-free morphometric analyses of the StW 573 atlas, along with other less complete hominin atlases from Sterkfontein (StW 679) and Hadar (AL 333-83), confirm the presence of an arboreal component in the positional repertoire of Australopithecus. Finally, assessment of the cross-sectional areas of the transverse foramina of the atlas and the left carotid canal in StW 573 further suggests there may have been lower metabolic costs for cerebral tissues in this hominin than have been attributed to extant humans and may support the idea that blood perfusion of these tissues increased over the course of hominin evolution.The DST-NRF for sponsoring the Micro-XCT facility at Necsa, and the DST-NRF and Wits University for funding the microfocus X-ray CT facility in the ESI. The Ghent University Special Research Fund (BOF-UGent) for the financial support of the Centre of Expertise UGCT (BOF.EXP.2017.0007), the Sterkfontein excavations and MicroCT scanning work have been provided by National Research Foundation and by PAST.http://www.nature.com/srepam2021Anatom

    Classification of 2.4-45.2 Micron Spectra from the ISO Short Wavelength Spectrometer

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    The Infrared Space Observatory observed over 900 objects with the Short Wavelength Spectrometer in full-grating-scan mode (2.4-45.2 micron). We have developed a comprehensive system of spectral classification using these data. Sources are assigned to groups based on the overall shape of the spectral energy distribution (SED). The groups include naked stars, dusty stars, warm dust shells, cool dust shells, very red sources, and sources with emission lines but no detected continuum. These groups are further divided into subgroups based on spectral features that shape the SED such as silicate or carbon-rich dust emission, silicate absorption, ice absorption, and fine-structure or recombination lines. Caveats regarding the data and data reduction, and biases intrinsic to the database, are discussed. We also examine how the subgroups relate to the evolution of sources to and from the main sequence and how this classification scheme relates to previous systems.Comment: 91 pages (40 for Table 6), 6 figures, accepted by ApJS. Figures 1-5 have degraded resolution due to astro-ph size limits. For full-resolution figures see: http://isc.astro.cornell.edu/~sloan/library/swsclass.html and for the classification table (Table 6) in ASCII format, see: http://isc.astro.cornell.edu/~sloan/library/cat.htm

    Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

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    This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin
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