Use of Geographic Information Systems by American Evaluation Association Members in their Professional Practice

Background: As geographic information systems (GIS) technology continues to develop and expand in its capacity and applications, it is becoming increasingly useful to many disciplines. Even so, little has been written about the place of GIS technology in evaluation practice, and there is a paucity of information as to the extent to and applications for which evaluation practitioners use such technology. Purpose: In this investigation, the prevalence and common applications of GIS technology in professional evaluation practice are examined. Particularly, the study was designed to estimate what proportion of American Evaluation Association (AEA) members who self-identify as evaluation practitioners use GIS in their practice, if at all, and, if so, to what extent. For those who use GIS in their evaluation practice, the specific GIS software packages and applications used also are explored. Setting: Not applicable. Intervention: Not applicable. Research Design: A simple random sample of American Evaluation Association (AEA) members were surveyed, with an emphasis on evaluation practitioners. Findings: Less than less than half (41.04% ±6.09%) of AEA members who consider themselves evaluation practitioners have ever used GIS in their evaluation practice and less than one-third (31.47% ±5.75%) have received some form of training in GIS methods. Data visualization is, by far, the most frequent application of GIS in evaluation practice. Keywords: American Evaluation Association; geographic information systems; technology in evaluation; evaluation practice; research on evaluatio

Civil society leadership in the struggle for AIDS treatment in South Africa and Uganda

Includes abstract.Includes bibliographical references.This thesis is an attempt to theorise and operationalise empirically the notion of ‘civil society leadership’ in Sub-Saharan Africa. ‘AIDS leadership,’ which is associated with the intergovernmental institutions charged with coordinating the global response to HIV/AIDS, is both under-theorised and highly context-specific. In this study I therefore opt for an inclusive framework that draws on a range of approaches, including the literature on ‘leadership’, institutions, social movements and the ‘network’ perspective on civil society mobilisation. This framework is employed in rich and detailed empirical descriptions (‘thick description’) of civil society mobilisation around AIDS, including contentious AIDS activism, in the key case studies of South Africa and Uganda. South Africa and Uganda are widely considered key examples of poor and good leadership (from national political leaders) respectively, while the Treatment Action Campaign (TAC) and The AIDS Support Organisation (TASO) are both seen as highly effective civil society movements. These descriptions emphasise ‘transnational networks of influence’ in which civil society leaders participated (and at times actively constructed) in order to mobilise both symbolic and material resources aimed at exerting influence at the transnational, national and local levels

Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion

Schizophrenia occurs in about one in four individuals with 22q11.2 deletion syndrome (22q11.2DS). The aim of this International Brain and Behavior 22q11.2DS Consortium (IBBC) study was to identify genetic factors that contribute to schizophrenia, in addition to the ~20-fold increased risk conveyed by the 22q11.2 deletion. Using whole-genome sequencing data from 519 unrelated individuals with 22q11.2DS, we conducted genome-wide comparisons of common and rare variants between those with schizophrenia and those with no psychotic disorder at age ≥25 years. Available microarray data enabled direct comparison of polygenic risk for schizophrenia between 22q11.2DS and independent population samples with no 22q11.2 deletion, with and without schizophrenia (total n = 35,182). Polygenic risk for schizophrenia within 22q11.2DS was significantly greater for those with schizophrenia (padj = 6.73 × 10−6). Novel reciprocal case–control comparisons between the 22q11.2DS and population-based cohorts showed that polygenic risk score was significantly greater in individuals with psychotic illness, regardless of the presence of the 22q11.2 deletion. Within the 22q11.2DS cohort, results of gene-set analyses showed some support for rare variants affecting synaptic genes. No common or rare variants within the 22q11.2 deletion region were significantly associated with schizophrenia. These findings suggest that in addition to the deletion conferring a greatly increased risk to schizophrenia, the risk is higher when the 22q11.2 deletion and common polygenic risk factors that contribute to schizophrenia in the general population are both present

Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

Use of Geographic Information Systems by American Evaluation Association Members in their Professional Practice

Background: As geographic information systems (GIS) technology continues to develop and expand in its capacity and applications, it is becoming increasingly useful to many disciplines. Even so, little has been written about the place of GIS technology in evaluation practice, and there is a paucity of information as to the extent to and applications for which evaluation practitioners use such technology. Purpose: In this investigation, the prevalence and common applications of GIS technology in professional evaluation practice are examined. Particularly, the study was designed to estimate what proportion of American Evaluation Association (AEA) members who self-identify as evaluation practitioners use GIS in their practice, if at all, and, if so, to what extent. For those who use GIS in their evaluation practice, the specific GIS software packages and applications used also are explored. Setting: Not applicable. Intervention: Not applicable. Research Design: A simple random sample of American Evaluation Association (AEA) members were surveyed, with an emphasis on evaluation practitioners. Findings: Less than less than half (41.04% ±6.09%) of AEA members who consider themselves evaluation practitioners have ever used GIS in their evaluation practice and less than one-third (31.47% ±5.75%) have received some form of training in GIS methods. Data visualization is, by far, the most frequent application of GIS in evaluation practice. Keywords: American Evaluation Association; geographic information systems; technology in evaluation; evaluation practice; research on evaluatio