Immobilization, Trapping, and Anion Exchange of Perrhenate Ion Using Copper-Based Tripodal Complexes

We describe a multidentate tripodal ligand in which three pendant arms carrying di(2-picolyl)amine units are linked to the ortho positions of a tris(o-xylyl) scaffold, providing N(CH[subscript 2]-o-C[subscript 6]H[subscript 4]CH[subscript 2]N(CH2py)[subscript 2])[subscript 3] (L). Reaction of L with CuCl[subscript 2] in the presence of hexafluorophosphate anion afforded blue cubes of [(CuCl)[subscript 3]L](PF[subscript 6])[subscript 3]·5H[subscript 2]O (1). Crystallographic studies of 1 revealed that the three symmetry-related arms each coordinate a {Cu[superscript II]Cl} unit, and two molecules of 1 are connected to one another through a Cu(μ-Cl)[subscript 2]Cu bridge, extending the molecular structure to form a two-dimensional (2-D) layer. These 2-D layers pack in an ABCABC... fashion with PF[subscript 6]– anions located in between. Reaction of 1 with a stoichiometric amount of perrhenate ion afforded blue plates of [(CuCl)[subscript 3]L](PF[subscript 6])(ReO[subscript 4])[subscript 2]·3H[subscript 2]O (2). Compound 2 has the same lattice structure as 1, but the tricopper unit backbone now traps one ReO[subscript 4]– anion through Coulombic interactions. In addition, three molecules of 2 are bridged by a perrhenate ion, forming a Cu[subscript 3](μ[superscript 3]-ReO[subscript 4]) cluster, to give a different 2-D structure displaying a rare tridentate bridging ReO[subscript 4]– mode. Thus, in addition to classic perrhenate trapping through weak Coulombic interactions, 2 represents an exceptional example in which the ReO[subscript 4]– anion is immobilized in an extended framework through tight covalent interactions. The interlamellar PF[subscript 6]– anions in 1 can be exchanged with other anions including perrhenate, perchlorate, or periodate. The structural similarity between perrhenate and pertechnetate makes these materials of potential interest for pertechnetate trapping

ОСТРОЕ ОТРАВЛЕНИЕ НИТРАТОМ НАТРИЯ В НЕВРОЛОГИЧЕСКОЙ ПРАКТИКЕ

This article describes a clinical case of a patient with acute cerebrovascular accident, acute respiratory failure and acute coronary syndrome. The ischemic lesion was associated with sodium nitrate, poisoning and its metabolite nitrite which resulted in increased methemoglobin concentration in blood and manifested as reversible discirculatory encephalopathy, respiratory disorder and myocardial damage. The article shows figures, reflecting changes in the biochemical composition of blood and changes in the electrocardiogram. The purpose of this study is to demonstrate clinical features of acute poisoning with sodium nitrate.В данной статье приводится описание клинического случая развития у пациента одновременно клинических симптомов острого нарушения мозгового кровообращения, острой дыхательной недостаточности и острого коронарного синдрома. Причиной развития ишемического поражения в данном случае явилось отравление нитратом натрия и его метаболитом — нитритом натрия, которое привело к повышенному содержанию метгемоглобина в крови, что в клинической картине выразилось обратимыми дисгемической энцефалопатией, нарушением дыхания и повреждением миокарда. В статье представлены графики и рисунки, отражающие изменения в биохимическом составе крови и на электрокардиограмме. Целью данной работы является демонстрация особенностей клинической картины острого отравления нитратом натрия и его метаболитом

The screening of the compounds with antiaggregation activity among benzimidazole and xantine

Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. We have synthesized L-65, on active compound, that suppresses platelet aggregation and has an acetylsalicylate acid-like effect. The results obtained concerning the screening of bioactive substances are promising

ACUTE POISONING WITH SODIUM NITRATE IN NEUROLOGICAL PRACTICE

This article describes a clinical case of a patient with acute cerebrovascular accident, acute respiratory failure and acute coronary syndrome. The ischemic lesion was associated with sodium nitrate, poisoning and its metabolite nitrite which resulted in increased methemoglobin concentration in blood and manifested as reversible discirculatory encephalopathy, respiratory disorder and myocardial damage. The article shows figures, reflecting changes in the biochemical composition of blood and changes in the electrocardiogram. The purpose of this study is to demonstrate clinical features of acute poisoning with sodium nitrate