STRATEGIC FLEXIBILITY: HOUSEHOLD ECOLOGIES OF FUL’BE IN TANOUT, NIGER

(Agro)pastoralism in Sahelian Niger, as elsewhere, operates through household enterprises. Katsinen-ko’en (Fulбe) households, interconnected within kin and community networks, utilize a range of flexible strategies to manage a variety of ecological and economic risks. This dissertation argues that (agro)pastoralist households and communities maintain or improve viability in risky environments first by employing various mobility patterns, among other strategies, and relying on the tightly knit interdependence between household and herd. Secondly, households that most successfully sustain a cooperative integrity (i.e. partnerships between husband and wife, or wives, and parents and children) to negotiate decisions and strategies best withstand adversities such as droughts. The continuance of vital links between household and herd helps the household enterprise more easily weather difficult times and profit during advantageous times. Thirdly, the transfer of endowments from parents to children of ecological, economic and political knowledges and socio-economic networks ensures the continuity of family livelihoods. This dissertation analyzes a range of household/herd mobility patterns on a livelihood continuum from sedentary agropastoralism to exclusive pastoralism, and the household decisions that lead to those mobilities. In this way, it adds to a growing body of literature that examines household strategies employed in very uncertain natural environments, contributing to pastoral studies and environmental anthropology. By folding household economics and political ecology into household ecology, it analyses resource and asset transfers within and between households, all under the influence of the natural and political-economic environments. Contributing to development anthropology, I argue that the most important buffer against the risks of unpredictable environments is a stable, undivided household, migrating with and managing its own herd. I conclude by showing how development research and projects should support household/herd integrity to enhance livelihood security. When government or development agencies institute policies and projects that remove children from the household, or separate households and herds, they endanger the integrity of the household and the reproduction of livelihoods that make essential contributions to national economies. Rather than urging pastoralists to modify their livelihoods to fit images held by ABSTRACT OF DISSERTATION administrators, these organizations and agencies should help pastoralists to build on adaptations that already facilitate their management of risky environments

DEVELOPMENT AGENTS AND NOMADIC AGENCY IN THE DAMERGOU, NIGER: FOUR PERSPECTIVES IN THE DEVELOPMENT MARKET

Discourse between development agents and nomads implies that development for nomadiccommunities is a contradiction in terms. A market-oriented subtext underscores the investors\u27power of international agencies, the brokers\u27 competition of intermediate organizations, and thenomadic clients\u27 opportunism. Interviews and participant-observation focused on relationsbetween Wo??aa??e communities, bilateral and local organizations, and government extensionservices. I compare the data obtained with historical events to illuminate current phenomena.Approaches of structuration, political ecology, and disequilibrium theory aid an examination ofcommunication and discourses, and gaps in understanding between the parties. I find thatessential pastoral livelihood strategies of mobility and customary institutions are threatened bythe development system. How will social change affect cultural mechanisms that facilitateresource access and allocation? Rather than promoting sustainable development, projects thattarget nomadic communities may only result in increased stratification, wealth disparity andmarginalization for the majority of nomadic households. Will development become too costlyfor households, local ecology, and even national economy? I conclude with recommendationsfor participative development through collaborative research

Stories of Change and Innovation in the Volta Basin Development Challenge Program

Innovation seems to be the lead buzz-word of the 2010 decade, a must for funding proposals. In this report, to go beyond buzz words and dictionary definitions, I try to tell stories of change and innovation within the Volta Basin Development Challenge, or CPWF-Volta, of CGIAR’s Challenge Program for Water and Food. The stories about change and innovation told in this report come from the people involved in the VBDC: the project team members and project participants. Has the VBDC produced innovations? The answer to that question would seem to depend on how one defines and perceives the changes in knowledge, practices and relationships of VBDC stakeholders. These definitions and perceptions depend on context and point of view. We found that different people, of different statuses, see innovation in different lights, but also that the VBDC projects have produced many changes. It is too early to say whether they will persist as innovations in the eyes of outside evaluators, but many in- country researchers and facilitators have seen and experienced what they call innovations in their partnerships with VBDC

Housing in Environmental Complexity Following Wheel Running Augments Survival of Newly-Generated Hippocampal Neurons in a Rat Model of Binge Alcohol Exposure during the Third Trimester Equivalent

Background Binge-like alcohol exposure in neonatal rats during the brain growth spurt causes deficits in adult neurogenesis in the hippocampal dentate gyrus (DG). Previous data from our lab demonstrated that twelve days of voluntary wheel-running (WR) beginning on postnatal day (PD) 30 significantly increased the number of newly-generated cells evident in the DG on PD42 in both alcohol-exposed and control rats, but 30 days later a sustained beneficial effect of WR was evident only in control rats. This study tested the hypothesis that housing rats in environmental complexity (EC) following WR would promote survival of the newly-generated cells stimulated by WR, particularly in alcohol-exposed rats. Methods On PD4-9, pups were intubated with alcohol in a binge-like manner (5.25g/kg/day), sham-intubated, or reared normally. In Experiment 1, animals were either assigned to WR during PD30-42 or were socially housed (SH). On PD42, animals were injected with bromodeoxyuridine (BrdU; 200mg/kg) and perfused two hours later to confirm the WR-induced stimulation of proliferation. In Experiment 2, all animals received WR on PD30-42 and were injected with BrdU on the last full day of WR. On PD42, animals were randomly assigned either to EC (WR/EC) or SH (WR/SH) for 30 days and subsequently perfused and brains were processed for immunohistochemical staining to identify BrdU+, Ki67+ and BrdU+/NeuN+ labeled cells in DG. Results In Exp. 1, WR exposure significantly increased the number of proliferating cells in all three postnatal conditions. In Exp. 2, the alcohol-exposed rats given WR/SH had significantly fewer BrdU+ cells compared to control rats given WR/SH. However, WR/EC experience significantly increased the number of surviving BrdU+ cells in both the alcohol-exposed and sham-intubated groups compared to WR/SH rats of the same neonatal treatment. Approximately 80% of the surviving BrdU+ cells in the DG across the conditions were co-labeled with NeuN. Conclusions WR followed by EC could provide a behavioral model for developing interventions in humans to ameliorate hippocampal-dependent impairments associated with fetal alcohol spectrum disorders

The genetic landscape of mutations in Burkitt lymphoma

Burkitt lymphoma is characterized by deregulation of MYC, but the contribution of other genetic mutations to the disease is largely unknown. Here, we describe the first completely sequenced genome from a Burkitt lymphoma tumor and germline DNA from the same affected individual. We further sequenced the exomes of 59 Burkitt lymphoma tumors and compared them to sequenced exomes from 94 diffuse large B-cell lymphoma (DLBCL) tumors. We identified 70 genes that were recurrently mutated in Burkitt lymphomas, including ID3, GNA13, RET, PIK3R1 and the SWI/SNF genes ARID1A and SMARCA4. Our data implicate a number of genes in cancer for the first time, including CCT6B, SALL3, FTCD and PC. ID3 mutations occurred in 34% of Burkitt lymphomas and not in DLBCLs. We show experimentally that ID3 mutations promote cell cycle progression and proliferation. Our work thus elucidates commonly occurring gene-coding mutations in Burkitt lymphoma and implicates ID3 as a new tumor suppressor gene

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Farmers' preferred tree species and their potential carbon stocks in southern Burkina Faso: Implications for biocarbon initiatives.

The success of terrestrial carbon sequestration projects for rural development in sub-Saharan Africa lies in the (i) involvement of local populations in the selection of woody species, which represent the biological assets they use to meet their daily needs, and (ii) information about the potential of these species to store carbon. Although the latter is a key prerequisite, there is very little information available. To help fill this gap, the present study was undertaken in four pilot villages (Kou, Dao, Vrassan and Cassou) in Ziro Province, south-central Burkina Faso. The objective was to determine carbon storage potential for top-priority woody species preferred by local smallholders. We used (i) participatory rural appraisal consisting of group discussions and key informant interviews to identify priority species and functions, and (ii) landscape assessment of carbon stocks in the preferred woody species. Results revealed 79 priority tree and shrub species grouped into six functions, of which medicine, food and income emerge as the most important ones for the communities. For these functions, smallholders overwhelmingly listed Vitellaria paradoxa, Parkia biglobosa, Afzelia africana, Adansonia digitata, Detarium microcarpum, and Lannea microcarpa among the most important tree species. Among the preferred woody species in Cassou and Kou, the highest quantity of carbon was stored by V. paradoxa (1180 ±209 kg C ha-1 to 2089±522 kg C ha-1) and the lowest by Grewia bicolor (5±1.2 kg C ha-1). The potential carbon stored by the preferred tree communities was estimated at 587.9 Mg C ha-1 (95% CI: 456.7; 719.1 Mg C ha-1) in Kou and256.8 Mg C ha-1 (95% CI: 67.6; 324.4 Mg C ha-1) in Cassou. The study showed that the species that farmers preferred most stored more carbon than species that were less preferred

Excess mortality in the aftermath of Hurricane Katrina: A preliminary report

Paul I. Kadetz - ORCID: 0000-0002-2824-1856 https://orcid.org/0000-0002-2824-1856Item not available in this repository.Background: Reports that death notices in the Times-Picayune, the New Orleans daily newspaper, increased dramatically in 2006 prompted local health officials to determine whether death notice surveillance could serve as a valid alternative means to confirm suspicions of excess mortality requiring immediate preventive actions and intervention. Methods: Monthly totals of death notices from the Times-Picayune were used to obtain frequency and proportion of deaths from January to June 2006. To validate this methodology the authors compared 2002 to 2003 monthly death frequency and proportions between death notices and top 10 causes of death from state vital statistics. Results: A significant (47%) increase in proportion of deaths was seen compared with the known baseline population. From January to June 2006, there were on average 1317 deaths notices per month for a mortality rate of 91.37 deaths per 100,000 population, compared with a 2002–2004 average of 924 deaths per month for a mortality rate of 62.17 deaths per 100,000 population. Differences between 2002 and 2003 death notices and top 10 causes of death were insignificant and had high correlation. Discussion: Death notices from local daily newspaper sources may serve as an alternative source of mortality information. Problems with delayed reporting, timely analysis, and interoperability between state and local health departments may be solved by the implementation of electronic death registration. (Disaster Med Public Health Preparedness. 2007;1:15–20)https://doi.org/10.1097/DMP.0b013e31806918561pubpub