Evaluation of the sensory properties, volatile aroma compounds and functional food potentials of cold-press produced mahaleb (Prunus mahaleb L.) seed oil☆

The aims of this study were to cold-press mahaleb seed, and then fully characterize the oil to extent its food and functional food applications. The novelty of this study relies upon the first data provided by the thermal analysis, sensory analysis, and volatile aroma compounds composition. The seeds were pressed with a screw-type single-head press with a maximum oil exit temperature of 40 °C. Most common physico-chemical properties, composition analyses, volatile aroma compounds profile, sensory descriptive analysis and consumer tests were completed. The main properties were appropriate and the composition (fatty acids, phytosterols and tocopherols) data concurred with the available literature. Thermal data were provided, and the oil peak crystallization and melting temperatures were −44.45 °C and −8.41 °C, respectively. There were 38 volatile aroma compounds quantified mostly with almond, green, vanillin, woody, and fermented aroma definitions. The panel described the oil with 5 sensory descriptive (almond, vanillin, dough, green, cooling) terms. Consumers liked appearance the most (4.49) with a general acceptance score of 3.70 on a 5-point hedonic scale. Overall, the mahaleb seed oil is a conjugated linolenic, oleic and linoleic fatty acids, β-sitosterol and γ-tocopherol rich, very aromatic, and consumer-liked sample. Further studies with various food applications are foreseen

How doest the retrocecal anatomic localization of the appendix vermiformis affect the prognosis of acute appendicitis today? A comparative prospective study

Appendix vermiformis is found in various anatomical localizations. Localization of the appendix vermiformis has been suggested to affect the clinical findings and outcomes of acute appendicitis. Aimed at investigating the effect of retrocecal localization of appendix vermiformis on the prognosis of acute appendicitis today. This study was started in August 2018 and finished in August 2021. Adult patients of both sexes who were operated in general surgery clinic with a pre-diagnosis of acute appendicitis were included in the study. Anatomic localization of appendix vermiformis were divided into two parts as retrocecal localizations and non-retrocecal localizations. The forms of appendicitis, postoperative complications, and length of hospitalization obtained from retrocecal and non-retrocecal localizations were compared and evaluated. A total of 776 patients were included in the study. Retrocecal localization was found in 15%, and non-retrocecal in 84.9% of the patients. The rate of acute appendicitis was 65.8% in retrocecal localization, 83.1% in non-retrocecal localization, perforated appendicitis at 31.6% in retrocecal localization and 11.2% in non-retrocecal localization. The perforated appendicitis rate was significantly higher in retrocecal localizations (p=.0001). Although postoperative complications were 5.1% in retrocecal appendicitis and 2.4% in non-retrocecal appendicitis, there was no significant difference between them in terms of postoperative complications (p=.105). The mean length of hospital stay was 2.4 days for appendicitis with retrocecal localization and 1.7 days for non-retrocecal localizations. The mean length of hospital stay was also significantly higher in retrocecal localizations (p=.0001). In conclusion, both perforated appendicitis rates and the mean length of hospital stay were higher in appendicitis with retrocecal localization. Therefore, appendicitis with retrocecal localization still negatively affects the prognosis of acute appendicitis today. [Med-Science 2022; 11(4.000): 1516-20

Synthesis and characterization of poly(m-tolyloxy-co-4-pyridinoxy phosphazene)s and their application as proton exchange membranes

A novel set of polyphosphazenes are synthesized to produce three polymers with varying side group ratios for proton exchange membranes. The designed heterosubstituted polymers here are the rare examples of polyphosphazenes of this kind to serve as proton exchange membranes with optimized structural stability and high temperature ionic conductivity. High quality polyphosphazenes with narrow polydispersity and rather low Tg values were prepared. These poly(m-tolyloxy-co-4-pyridinoxy phosphazene)s are sulfonated under a range of conditions and characterized in order to investigate the synergetic effect of the heteroatom on the proton conductivity of the proton exchange membranes. The effect of sulfonation temperature and time on the fuel cell relevant properties is also investigated. Hydrolytically stable proton exchange membranes with high thermal and chemical stabilities are achieved. Additionally, resultant membranes exhibit proton conductivity, IEC and water uptake values comparable with commercial Nafion® membranes

Avaliação da comunicação de psiquiatras com pacientes psicóticos

Evaluation of the physician-patient relationship is very important in determining priorities in medical practice and medicine. For this purpose, in this study the psychiatrist’s communication with psychotic patients as a sensitive group was evaluated. A questionnaire was administered to 210 patients in a psychiatric clinic of Inonu University Hospital in Turkey to determine how the examination is performed in the facility for outpatients in the psychosis unit. According to the study conducted, it was observed that the evaluation score of the psychiatrist's communication with psychotic patients increased positively with increasing consultation duration. Our work is particularly noteworthy because it deals with a sensitive area, such as a group of psychiatric patients. The scores were obtained based on data from the evaluation of the questionnaires, which showed that the communication between the psychiatrist and the psychotic patient was conducted in a sensitive and careful manner, and without ethical problems.La evaluación de la relación médico-paciente es muy importante para determinar las prioridades en la práctica médica y la medicina. Para este propósito, en este estudio se evaluó la comunicación del médico psiquiatra con los pacientes psicóticos como grupo sensible. Se administró un cuestionario a 210 pacientes de una clínica psiquiátrica del Hospital de la Universidad de Inonu en Turquía, para determinar cómo se realiza el examen en el establecimiento para los pacientes externos de la unidad de psicosis. De acuerdo con el estudio realizado, se observó que el puntaje de evaluación de la comunicación del psiquiatra con los pacientes psicóticos se incrementó positivamente al aumentar la duración de la consulta. Nuestro trabajo se destaca particularmente por tratarse de un área sensible, como es un grupo de pacientes psiquiátricos. Los puntajes se obtuvieron basándose en datos de la evaluación de los cuestionarios, que mostraron que la comunicación entre el psiquiatra y el paciente psicótico se realizó de una forma sensible y cuidadosa, y sin problemas éticos.A avaliação da relação médico-paciente é muito importante para determinar as prioridades na prática médica e na medicina. Para este fim, neste estudo foi avaliada a comunicação do psiquiatra com pacientes psicóticos como um grupo sensível. Um questionário foi aplicado a 210 pacientes em uma clínica psiquiátrica do Hospital Universitário Inonu na Turquia para determinar como o exame é conduzido nas instalações para pacientes ambulatoriais da unidade de psicose. De acordo com o estudo realizado, observou-se que a pontuação da avaliação da comunicação do psiquiatra com pacientes psicóticos aumentou positivamente à medida que a duração da consulta aumentava. Nosso trabalho é particularmente notável porque trata de uma área sensível, tal como um grupo de pacientes psiquiátricos. Os resultados foram obtidos com base nos dados da avaliação dos questionários, que mostraram que a comunicação entre psiquiatra e paciente psicótico foi realizada de forma sensível e cuidadosa, e sem problemas éticos

Application of Project-Based Learning in a Theoretical Course: Process, Difficulties and Recommendations

This paper presents a case study about the application of a project-based learning approach. In this case study, software development projects are performed by the students, using historical software development methods in order to demonstrate evolution of the subject. The presented case study differs from others reported in the literature in its utilization of historical methods for project execution. Getting feedback and reaction of students and assessing the success of the project-based learning implementation employed are the main objectives of the case study. Concluding the case study, critical points concerning this project-based learning implementation are identified and recommendations for similar implementations are mentioned

A serious dermatological side effect due to vortioxetine: a case report

Major depressive disorder is the second-largest healthcare problem worldwide in terms of illness-induced disability, and second-generation antidepressants are the most commonly used treatments in this disorder. Vortioxetine is a recently introduced antidepressant with a multimodal mechanism of action. Some side effects associated with the use of vortioxetine have been reported. Side effects that do not occur in clinical trials can be reported during phase IV studies. In this case report, we present a patient who developed dermatological adverse reactions following vortioxetine use

Evaluating the Behaviours of Citizens and Physicians During Healthcare System Changes in Turkey

This study may provide insights into the positive and negative perceptions of physicians and citizens in Turkey regarding the Transformation in Health Project.We aimed to evaluate the views of physicians and citizens regarding the changing healthcare system using different questionnaires.We interviewed 1190 actively working physicians and 1997 citizens using face-to-face questionnaires to determine how the changing healthcare system has affected the behaviours of physicians and citizens. When asked whether the behaviours of patients and relatives had improved, 495 physicians (41.6%) answered yes and 580 (48.7%) answered no. When citizens were asked whether the behaviours of physicians had improved, 1399 (70.1%) answered yes and 362 (18.1%) answered no. According to the results of this study, there have been some changes in our healthcare system associated with the Transformation in Health Project. [Med-Science 2016; 5(2.000): 505-18