Benign Tumors of Temporomandibular Joint

The temporomandibular joint (TMJ) forms a complex functional system with teeth, bones, connected muscles and ligaments. Any discomfort in any of these structures directly affects the joint. The complaints are mostly pain, malocclusion and swelling. Temporomandibular joint tumors are very uncommon but show symptoms similar to intra-articular disorders that make up most of these disorders. The most common TMJ-specific benign tumors are classified after a brief literature review. Our classification also includes the osteoma of the TMJ, other than World Health Organization’s (WHO) classification of soft tissue and bone tumors. This benign tumor was also included in the classification because of its higher frequency in the literature. The treatment of these neoplasms may be conservative or radical surgery

“Near miss” maternal morbidity following repeat rescue cerclage for twin pregnancy

Objective Repeat cervical cerclage is one of the treatment options described in the literature for when the primary cerclage suture fails. However, infectious complications of cerclage placement may be encountered which are more obvious for the newborn. In our presented case, severe acute maternal morbidity was encountered for the sake of prolonging pregnancy. Case(s) Twenty-seven year old nullipar patient at 23+5 gestational weeks with dichorionic diamniotic pregnancy was admitted to our emergency clinic with complaints of “pain” and “vaginal bleeding”. At 18 weeks of pregnancy she had a Shirodkar cerclage procedure indicated by a short cervical length (14 mm) at our hospital. She presented with “bulging of membranes” to a different institution and underwent a repeat cerclage at 23+3 weeks. Chorioamnionitis was suspected and the patient was counselled for a pregnancy termination. After termination of pregnancy, “cardiac arrest” developed. After 2 minutes of resuscitation sinus rythm was obtained. The patient was admitted to the ICU. Conclusion The role of repeat cerclage is controversial. Efforts should be maximized to rule out underlying intrauterine infection prior to placement of a cerclage suture for there to be a therapeutic benefit of prolonging the pregnancy

Assessment of the compliance with minimum acceptable technical parameters proposed by PI-RADS v2 guidelines in multiparametric prostate MRI acquisition in tertiary referral hospitals in the Republic of Turkey

PURPOSEAlthough the clinical use of multiparametric prostate magnetic resonance imaging (mpMRI) is increasing, the adherence to parameters for mpMRI, which had been described in the Prostate Imaging-Reporting and Data System version 2 (PI-RADS v2) for an optimum image acquisition is unknown. In this paper, we aimed to determine the compliance with the minimum acceptable technical parameters for prostate mpMRI defined by PI-RADS v2 in tertiary care centers in Turkey.METHODSWe sent a survey to all radiology departments of tertiary referral hospitals in Turkey (n=120) to evaluate their adherence to PI-RADS v2 technical specifications. Statistical analysis was performed using chi-square, Fisher exact, ANOVA, and the Student t tests. The cutoff values for image acquisition times were also determined with receiver operating characteristics (ROC) analysis. P values <0.05 were considered statistically significant.RESULTSOne hundred and eleven clinics responded to our survey (response rate, 92.5%). Prostate MRI was reported to be performed in 61 centers, of which 26 (42.6%) used 3 T (Tesla) scanner while 35 (57.4%) used 1.5 T. The adherence to slice thickness, in-plane phase and frequency resolutions on T2-weighted imaging were 68.9%, 41%, and 9.8%, respectively. The adherence to the same parameters on diffusion-weighted imaging (DWI) were higher compared with T2-weighted imaging (85.2%, 62.3%, and 78.7%, respectively). In comparative analysis, the adherence to slice thickness, field of view (FOV) and in-plane phase resolution on T2-weighted imaging were higher for 3 T compared with 1.5 T scanners (P = 0.004, P = 0.041, and P = 0.001, respectively). T2-weighted imaging acquisition time was significantly longer for the centers that adhered to FOV (P = 0.034) and in-plane T2-weighted imaging phase resolution (P = 0.028). The DWI scan time was significantly longer when they adhered to DWI-FOV (P = 0.014) and b value ≥1400 s/mm2 (P = 0.008). The calculated cutoff of scan times were 220 s in T2-weighted imaging and 312 s in DWI to ensure the compliance with voxel sizes and b value criteria.CONCLUSIONThe tertiary referral centers in Turkey did not meet majority of the technical specifications of PI-RADS v2 during prostate MRI acquisition. Awareness to the minimum acceptable technical parameters of mpMRI should be increased to potentially improve the quality of prostate cancer imaging

Real-world efficacy and safety of Ledipasvir plus Sofosbuvir and Ombitasvir/Paritaprevir/Ritonavir +/- Dasabuvir combination therapies for chronic hepatitis C: A Turkish experience

Background/Aims: This study aimed to evaluate the real-life efficacy and tolerability of direct-acting antiviral treatments for patients with chronic hepatitis C (CHC) with/without cirrhosis in the Turkish population.Material and Methods: A total of 4,352 patients with CHC from 36 different institutions in Turkey were enrolled. They received ledipasvir (LDV) and sofosbuvir (SOF)+/- ribavirin (RBV) ombitasvir/paritaprevir/ritonavir +/- dasabuvir (PrOD)+/- RBV for 12 or 24 weeks. Sustained virologic response (SVR) rates, factors affecting SVR, safety profile, and hepatocellular cancer (HCC) occurrence were analyzed.Results: SVR12 was achieved in 92.8% of the patients (4,040/4,352) according to intention-to-treat and in 98.3% of the patients (4,040/4,108) according to per-protocol analysis. The SVR12 rates were similar between the treatment regimens (97.2%-100%) and genotypes (95.6%-100%). Patients achieving SVR showed a significant decrease in the mean serum alanine transaminase (ALT) levels (50.90 +/- 54.60 U/L to 17.00 +/- 14.50 U/L) and model for end-stage liver disease (MELD) scores (7.51 +/- 4.54 to 7.32 +/- 3.40) (p<0.05). Of the patients, 2 were diagnosed with HCC during the treatment and 14 were diagnosed with HCC 37.0 +/- 16.0 weeks post-treatment. Higher initial MELD score (odds ratio [OR]: 1.92, 95% confidence interval [CI]: 1.22-2.38; p=0.023]), higher hepatitis C virus (HCV) RNA levels (OR: 1.44, 95% CI: 1.31-2.28; p=0.038), and higher serum ALT levels (OR: 1.38, 95% CI: 1.21-1.83; p=0.042) were associated with poor SVR12. The most common adverse events were fatigue (12.6%), pruritis (7.3%), increased serum ALT (4.7%) and bilirubin (3.8%) levels, and anemia (3.1%).Conclusion: LDV/SOF or PrOD +/- RBV were effective and tolerable treatments for patients with CHC and with or without advanced liver disease before and after liver transplantation. Although HCV eradication improves the liver function, there is a risk of developing HCC.Turkish Association for the Study of The Liver (TASL

Climate anxiety, wellbeing and pro-environmental action: correlates of negative emotional responses to climate change in 32 countries

This study explored the correlates of climate anxiety in a diverse range of national contexts. We analysed cross-sectional data gathered in 32 countries (N = 12,246). Our results show that climate anxiety is positively related to rate of exposure to information about climate change impacts, the amount of attention people pay to climate change information, and perceived descriptive norms about emotional responding to climate change. Climate anxiety was also positively linked to pro-environmental behaviours and negatively linked to mental wellbeing. Notably, climate anxiety had a significant inverse association with mental wellbeing in 31 out of 32 countries. In contrast, it had a significant association with pro-environmental behaviour in 24 countries, and with environmental activism in 12 countries. Our findings highlight contextual boundaries to engagement in environmental action as an antidote to climate anxiety, and the broad international significance of considering negative climate-related emotions as a plausible threat to wellbeing.publishedVersio

Climate anxiety, wellbeing and pro-environmental action : correlates of negative emotional responses to climate change in 32 countries

Publisher Copyright: © 2022 The AuthorsThis study explored the correlates of climate anxiety in a diverse range of national contexts. We analysed cross-sectional data gathered in 32 countries (N = 12,246). Our results show that climate anxiety is positively related to rate of exposure to information about climate change impacts, the amount of attention people pay to climate change information, and perceived descriptive norms about emotional responding to climate change. Climate anxiety was also positively linked to pro-environmental behaviours and negatively linked to mental wellbeing. Notably, climate anxiety had a significant inverse association with mental wellbeing in 31 out of 32 countries. In contrast, it had a significant association with pro-environmental behaviour in 24 countries, and with environmental activism in 12 countries. Our findings highlight contextual boundaries to engagement in environmental action as an antidote to climate anxiety, and the broad international significance of considering negative climate-related emotions as a plausible threat to wellbeing.Peer reviewe

Climate anxiety, wellbeing and pro-environmental action: Correlates of negative emotional responses to climate change in 32 countries

This study explored the correlates of climate anxiety in a diverse range of national contexts. We analysed cross-sectional data gathered in 32 countries (N = 12,246). Our results show that climate anxiety is positively related to rate of exposure to information about climate change impacts, the amount of attention people pay to climate change information, and perceived descriptive norms about emotional responding to climate change. Climate anxiety was also positively linked to pro-environmental behaviours and negatively linked to mental wellbeing. Notably, climate anxiety had a significant inverse association with mental wellbeing in 31 out of 32 countries. In contrast, it had a significant association with pro-environmental behaviour in 24 countries, and with environmental activism in 12 countries. Our findings highlight contextual boundaries to engagement in environmental action as an antidote to climate anxiety, and the broad international significance of considering negative climate-related emotions as a plausible threat to wellbeing

Gruplararası ilişkilerde çatışma ve barış süreçlerinin sosyal psikolojik arka planı

Bu çalışmanın amacı, Türkiye'de yaşayan insanların Ermeni meselesine ilişkin algı ve değerlendirmelerini Q yöntemi kullanarak incelemektir. Buna göre farklı ideolojik ve dini yönelimlerden 72 katılımcıyla bir alan araştırması gerçekleştirilmiştir. Katılımcılardan Ermeni meselesine ilişkin 41 fikir kartını "en çok katıldıkları" noktalardan (+4) "hiç katılmadıkları" noktalara (-4) doğru sıralamaları istenmiştir. Veriler PQMethod 2.35 programı ile analiz edilmiştir. Sonuçlara göre, Ermeni meselesine ilişkin farklı bakış açılarını temsil eden 3 faktör tanımlanmıştır: 1) "Soykırım olarak Ermeni Meselesi ve Tek (Politik) Sorumlu Taraf olarak Türkiye", 2) "Acıların Ortaklaştırılması ve Sorumluluğun Dışsallaştırılması Açısından Ermeni Meselesi" ve 3) "Soykırımın Reddi Açısından Ermeni Meselesi ve Resmi Anlatı". Sonuçlar katılımcıların Ermeni meselesine ilişkin algı ve değerlendirmelerinde çeşitli uzlaşma ve ayrışma noktalarının olduğunu da göstermiştir. Buna göre, katılımcıların Ermeni meselesinin çözümüne ilişkin karşılıklı adımları içeren görüşlerde uzlaştığını; ancak bu meseleye ilişkin aşırı politikleşmiş çözüm önerilerinde ayrıştıklarını göstermektedir. Sonuçlar; Zorlu Çatışmalar, Sosyal Temsiller ve Kolektif Suçluluk Kuramları çerçevesinde tartışılmıştır.The aim of this study is to examine the perceptions and evaluations of people living in Turkey towards the 'Armenian issue' by using Q methodology. A field research was carried out with 72 participants from different ideological and religious backgrounds in Turkey. The participants were asked to sort 41 different cards related to the Armenian issue from "the most agreed" (+4) to "the most disagreed" side (-4). The data were analyzed with the PQMethod 2.35 program. The results highlighted three factors representing different aspects of the Armenian issue: 1) "Armenian Issue as a Genocide and Turkish State as the Only (Political) Responsible Party", 2) "Armenian Issue as Mutual Sufferings and the Externalization of Responsibility", 3) "Armenian Issue as the Rejection of Genocide and Official Narrative". The results also indicated the participants' agreement and disagreement points. The participants had a consensus on views involving reciprocal steps to solve the issue such as conducting scientific studies and various activities of research institutions and NGOs from both countries and restarting the diplomatic relations. However, they diverged on views including politicized suggestions for the solutions of the Armenian issue such as a request for recognition of genocide, request for official apology. The results were discussed within the framework of Intractable Conflicts, Social Representations and Collective Guilt Theories