Toward an analytical threshold function of the two Lepton pair production in Gamma-Gamma collisions

International audienceThe analytical asymptotic cross section for arbitrary masses was given a fewyears ago. Obtaining an analytical approach of the onset of the asymptoticregime is an interesting challenge

Myocardial function in children after fetal chemotherapy exposure. A tissue Doppler and myocardial deformation imaging study

Item does not contain fulltextChemotherapy and particularly anthracycline exposure are associated with acute and chronic cardiotoxicity. Few data exist on the effect of cardiac function after in utero exposure to maternal chemotherapy. Our recently published multicenter prospective study showed no significant changes in systolic function using conventional echocardiographic parameters. The purpose of this study was to further investigate whether early functional changes can be detected using tissue Doppler imaging (TDI) and two-dimensional (2D) speckle tracking echocardiography (STE). Sixty-two children (median/range age 1.7 (1-9.8) years) exposed to chemotherapy during fetal life were enrolled and compared to 62 age- and gender-matched controls. TDI velocities were measured at the basal interventricular septum (IVS) and right and left ventricular (LV) free walls. LV global longitudinal and circumferential systolic strains were derived using 2D STE. We found small but significant differences between the groups (patients versus controls) in LV fractional shortening [35 (29-46)% versus 39 (28-53)%, p < 0.001], LV ejection fraction [66 (57-79)% versus 70 (57-83)%, p < 0.001], LV posterior wall thickness z score [-0.15 (-2.32-1.81) versus -0.10 (-1.9-2.0), p < 0.001], and IVS thickness z score [-1.06 (-2.6-1.3) versus -0.5 (-2.1-1.7), p < 0.001]. No significant differences in TDI velocities or LV global strains were observed. Within the patient group, the cardiac functional parameters did not correlate to the number of cycles of anthracycline or the cumulative anthracycline dose. Children exposed to fetal chemotherapy have a lower normal fractional shortening and mildly lower left ventricular wall thickness. Tissue Doppler and strain measurements are within normal range and not statistically different from normal controls. The long-term implications of these findings will be further studied in this prospective cohort study

Actes de la conférence CAID 2021 (Conference on Artificial Intelligence for Defense)

6th European Cyber Week (6ème semaine européenne de la cybersécurité et de la cyberdéfense

Actes de la conférence CAID 2021 (Conference on Artificial Intelligence for Defense)

6th European Cyber Week (6ème semaine européenne de la cybersécurité et de la cyberdéfense)International audienc

Actes de la conférence CAID 2021 (Conference on Artificial Intelligence for Defense)

6th European Cyber Week (6ème semaine européenne de la cybersécurité et de la cyberdéfense

Actes de la conférence CAID 2021 (Conference on Artificial Intelligence for Defense)

6th European Cyber Week (6ème semaine européenne de la cybersécurité et de la cyberdéfense)International audienc

Actes de la conférence CAID 2021 (Conference on Artificial Intelligence for Defense)

6th European Cyber Week (6ème semaine européenne de la cybersécurité et de la cyberdéfense)International audienc

Actes de la conférence CAID 2021 (Conference on Artificial Intelligence for Defense)

6th European Cyber Week (6ème semaine européenne de la cybersécurité et de la cyberdéfense)International audienc

Actes de la conférence CAID 2020

National audienc

ILC Reference Design Report Volume 1 - Executive Summary

The International Linear Collider (ILC) is a 200-500 GeV center-of-mass high-luminosity linear electron-positron collider, based on 1.3 GHz superconducting radio-frequency (SCRF) accelerating cavities. The ILC has a total footprint of about 31 km and is designed for a peak luminosity of 2x10^34 cm^-2s^-1. This report is the Executive Summary (Volume I) of the four volume Reference Design Report. It gives an overview of the physics at the ILC, the accelerator design and value estimate, the detector concepts, and the next steps towards project realization.The International Linear Collider (ILC) is a 200-500 GeV center-of-mass high-luminosity linear electron-positron collider, based on 1.3 GHz superconducting radio-frequency (SCRF) accelerating cavities. The ILC has a total footprint of about 31 km and is designed for a peak luminosity of 2x10^34 cm^-2s^-1. This report is the Executive Summary (Volume I) of the four volume Reference Design Report. It gives an overview of the physics at the ILC, the accelerator design and value estimate, the detector concepts, and the next steps towards project realization