5,497 research outputs found

    Effect of Height-To-Width Ratio on the Sound Propagation in Urban Streets

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    Street geometry is one of main issues on urban design which influence sound environment as well as urban climate in a street canyon. A parametric study was performed in order to investigate the influence of height-to-width ratio (H/W) on sound fields in urban streets in terms of sound pressure level (SPL), reverberation time (T30), and early decay time (EDT). A computer simulation technique based on a hybrid method combining ray tracing and image source modeling was adopted, and an omnidirectional sound source was used. Four typical idealized urban streets were modeled, with street widths of 6 m, 13 m, 20 m, and 27 m, respectively. The H/W ratio was then changed in seven steps with varying building heights while the widths of streets were fixed. Comparisons with experimental studies showed that the computer simulation models produce reliable results for SPL and T30. It was found that the variation of SPL was affected by the H/W ratio only for narrow urban streets, and the T30 and EDT increased with an increase in the H/W ratio for both narrow and wide streets. It was also observed that the T30 decreased with increasing scattering coefficients, and the EDT significantly increased as scattering coefficients increased for H/W of 3 and 6. A line source representing road traffic noise was found to produce different tendencies in SPL and EDT, showing that SPL and EDT were relatively constant along the length

    A Comparison between the Zero Forcing Number and the Strong Metric Dimension of Graphs

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    The \emph{zero forcing number}, Z(G)Z(G), of a graph GG is the minimum cardinality of a set SS of black vertices (whereas vertices in V(G)SV(G)-S are colored white) such that V(G)V(G) is turned black after finitely many applications of "the color-change rule": a white vertex is converted black if it is the only white neighbor of a black vertex. The \emph{strong metric dimension}, sdim(G)sdim(G), of a graph GG is the minimum among cardinalities of all strong resolving sets: WV(G)W \subseteq V(G) is a \emph{strong resolving set} of GG if for any u,vV(G)u, v \in V(G), there exists an xWx \in W such that either uu lies on an xvx-v geodesic or vv lies on an xux-u geodesic. In this paper, we prove that Z(G)sdim(G)+3r(G)Z(G) \le sdim(G)+3r(G) for a connected graph GG, where r(G)r(G) is the cycle rank of GG. Further, we prove the sharp bound Z(G)sdim(G)Z(G) \leq sdim(G) when GG is a tree or a unicyclic graph, and we characterize trees TT attaining Z(T)=sdim(T)Z(T)=sdim(T). It is easy to see that sdim(T+e)sdim(T)sdim(T+e)-sdim(T) can be arbitrarily large for a tree TT; we prove that sdim(T+e)sdim(T)2sdim(T+e) \ge sdim(T)-2 and show that the bound is sharp.Comment: 8 pages, 5 figure

    Simulations of extensional flow in microrheometric devices

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    We present a detailed numerical study of the flow of a Newtonian fluid through microrheometric devices featuring a sudden contraction–expansion. This flow configuration is typically used to generate extensional deformations and high strain rates. The excess pressure drop resulting from the converging and diverging flow is an important dynamic measure to quantify if the device is intended to be used as a microfluidic extensional rheometer. To explore this idea, we examine the effect of the contraction length, aspect ratio and Reynolds number on the flow kinematics and resulting pressure field. Analysis of the computed velocity and pressure fields show that, for typical experimental conditions used in microfluidic devices, the steady flow is highly three-dimensional with open spiraling vortical structures in the stagnant corner regions. The numerical simulations of the local kinematics and global pressure drop are in good agreement with experimental results. The device aspect ratio is shown to have a strong impact on the flow and consequently on the excess pressure drop, which is quantified in terms of the dimensionless Couette and Bagley correction factors. We suggest an approach for calculating the Bagley correction which may be especially appropriate for planar microchannels

    Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.

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    Gas1 and Boc/Cdon act as co-receptors in the vertebrate Hedgehog signalling pathway, but the nature of their interaction with the primary Ptch1/2 receptors remains unclear. Here we demonstrate, using primordial germ cell migration in mouse as a developmental model, that specific hetero-complexes of Ptch2/Gas1 and Ptch1/Boc mediate the process of Smo de-repression with different kinetics, through distinct modes of Hedgehog ligand reception. Moreover, Ptch2-mediated Hedgehog signalling induces the phosphorylation of Creb and Src proteins in parallel to Gli induction, identifying a previously unknown Ptch2-specific signal pathway. We propose that although Ptch1 and Ptch2 functionally overlap in the sequestration of Smo, the spatiotemporal expression of Boc and Gas1 may determine the outcome of Hedgehog signalling through compartmentalisation and modulation of Smo-downstream signalling. Our study identifies the existence of a divergent Hedgehog signal pathway mediated by Ptch2 and provides a mechanism for differential interpretation of Hedgehog signalling in the germ cell niche

    Asymmetric Origin for Gravitino Relic Density in the Hybrid Gravity-Gauge Mediated Supersymmetry Breaking

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    We propose the hybrid gravity-gauge mediated supersymmetry breaking where the gravitino mass is about several GeV. The strong constraints on supersymmetry viable parameter space from the CMS and ATLAS experiments at the LHC can be relaxed due to the heavy colored supersymmetric particles, and it is consistent with null results in the dark matter (DM) direct search experiments such as XENON100. In particular, the possible maximal flavor and CP violations from the relatively small gravity mediation may naturally account for the recent LHCb anomaly. In addition, because the gravitino mass is around the asymmetric DM mass, we propose the asymmetric origin of the gravitino relic density and solve the cosmological coincident problem on the DM and baryon densities \Omega_{\rm DM}:\Omega_{B}\approx 5:1. The gravitino relic density arises from asymmetric metastable particle (AMP) late decay. However, we show that there is no AMP candidate in the minimal supersymmetric Standard Model (SM) due to the robust gaugino/Higgsino mediated wash-out effects. Interestingly, AMP can be realized in the well motivated supersymmetric SMs with vector-like particles or continuous U(1)_R symmetry. Especially, the lightest CP-even Higgs boson mass can be lifted in the supersymmetric SMs with vector-like particles.Comment: RevTex4, 21 pages, 1 figure, minor corrections, JHEP versio

    Teasing Apart the Impact of Illness and IQ on Functional Neuroimaging Findings in Schizophrenia

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    Schizophrenia is a major psychiatric disorder associated with cognitive impairment. Functional brain imaging (fMRI) studies of schizophrenia patients reveal a complex pattern of brain differences in the prefrontal cortex. Both decreased (hypofrontality) and increased (hyperfrontality) activity have been reported in patients – inconsistencies that this paper argues could be explained by differences in IQ between patients and healthy controls. This study demonstrates a novel method to tease apart IQ and schizophrenia effects on brain activity. Twelve schizophrenia patients were matched to twelve healthy controls matched to patients’ estimated (premorbid) IQ before their illness, and twelve healthy controls matched to patients’ measured current IQ. All participants performed an executive function event-related fMRI task. Schizophrenia patients’ mean behavioral scores fell numerically between those of both control groups, and did not differ significantly from either group. Two distinct patterns of brain activity were found that were consistent with an effect due to either IQ impairment or schizophrenia diagnosis. Schizophrenia patients’ relatively reduced activity in middle/superior frontal (BA6/BA8) regions was related to their schizophrenia diagnosis, whereas their relatively increased activity in inferior frontal (BA44/45) and left middle frontal (BA8/9) regionsrelated instead to their current IQ impairment. These findings indicate that some fMRI differences reported in schizophrenia patients are artefacts of IQ matching. After removing the IQ confounds, schizophrenia was associated with lateral frontal hypoactivations and medial frontal failure of deactivation. This paper proposes a method to address IQ matching-related issues when studying populations where their illness involves cognitive deterioration
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