14 research outputs found
Stereoselective Synthesis of Novel Dispiro Oxindole-pyrrolothiazole-androsterone Hybrids
Four-Component Domino Strategy for the Combinatorial Synthesis of Novel 1,4-Dihydropyrano[2,3‑<i>c</i>]pyrazol-6-amines
An
efficient one-pot four-component domino protocol for the combinatorial
synthesis of novel 1,4-dihydropyranoÂ[2,3-<i>c</i>]Âpyrazol-6-amines
has been achieved. This transformation presumably occurs via cyclization–Knoevenagel
condensation–Michael addition–tautomerism–intramolecular <i>O</i>-cyclization–elimination sequence of reactions.
The significant features of this reaction include expedient one-pot
process, short reaction time, no column chromatographic purification,
excellent yield, and readily available starting materials