Building Simulation, Solar Potential and Consumption Analysis of Residential Dwellings, in Dubai

City sustainability analysis is overly broad, and people with diverse mindsets look at cities from different perspectives. As part of the city’s fabric, buildings are an integral component and hence require attention. Although the electricity consumed in buildings varies from country to country, it is equal to 30–40% of the total electricity consumption all over the world. [1]. This research targeted studying residential building simulation in Dubai, using various Green Building Codes, assessing energy consumption trends, designing solar systems with respective sizing along with conducting detailed load profile analysis and developing statistical model to directly estimate the HVAC consumption. The results showed that Green Building Codes progression and enhancements have reduced energy consumption gradually, totaling a 37.87% drop at Al Sa’fat Platinum compared to a base case. The EUI for Al Sa’fat Platinum residential villa is 151 KW/m2 and is approximately 60% above the nZEB targets for UAE. Optimum solar PV tilt angles are 25O, south facing, and Al Sa’fat Platinum 10% on-site solar energy mandate results in a payback period of 5 years and compensates 16% of grid import costs. Furthermore, the load profile analysis studied the average day load profiles and changes in load shape for various codes and statistical modeling of villa consumption showed that the about 33% of the Weather Independent Consumption contributed to HVAC consumption share

Helicobacter pylori genotypes identified in gastric biopsy specimens from Jordanian patients

BACKGROUND: The genetic diversity of Helicobacter pylori can be analyzed at two different levels: the genomic variation between strains originating from different individuals, and the variation in bacterial populations within an individual host. We reported for the first time the H. pylori genotypes in Jordanian patients with gastrointestinal diseases. METHODS: Upper endoscopy was performed on 250 patients with symptoms of gastrointestinal diseases. Multiple gastric biopsy specimens were taken from the antrum. All the biopsies were tested by PCR for the H. pylori virulence genes vacA, cagA, and iceA, and 151 were tested by histology. RESULTS: The biopsies positive for H. pylori by PCR were 110/250 (44%), and by histology 117/151 (77.5%), and these results were highly associated (P < 0.02). Analyses of virulence genes revealed that iceA2 (73.6%) was the predominant genotype, the vacAs2 allele was more frequently identified than the vacAs1 allele, while the cagA genotype was low (26.4%). The presence of certain genotypes might be associated with each other, but the presence of certain genotypes was not significantly associated with the age, or gender of the patient. CONCLUSION: The results illustrate the geographic nature of the genetic diversity of H. pylori, as the identified genotypes are similar to those reported in neighboring countries. This study provides a baseline data of H. pylori genotypes identified in gastric biopsy specimens from Jordan, serving as a powerful epidemiological tool for prospective investigations to better understand the genetic diversity of this pathogen

High-resolution Melting Curve (HRM) analysis in genotypic discrimination of Cryptosporidium isolates from stool of Egyptian children

Cryptosporidiosis is a recognized child infectious killer and the second cause of diarrheal disease and death in infants. Assessing Cryptosporidium spp. genetic diversity is a real goal to elucidate its transmission dynamics and to design preventive measures in absence of effective treatment. Cryptosporidium isolates in stool of Egyptian children were detected using Acid Fast (AF) staining, copro-nPCR/RFLP assay and real time PCR high-resolution melting (HRM) curve analysis assay. Stool samples were collected from 335 children complaining of diarrhea and other GIT symptoms, attending the outpatient clinic of Abu El Reesh hospital, Kasr Al-Ainy School of Medicine, Cairo University. Two genotypes C. hominis and C. parvum were identified in 43 isolates from Egyptian children by copro-nPCR targeting COWP gene and HRM assay. Real time PCR HRM curve analysis, a closed-tube genotyping method, targeting ITS-2 gene confirmed the results of copro-nPCR/RFLP. It is simple, rapid, has more sample throughput, analysis capacities and data storage with less carry-over contamination and cost

CAFFEINEAS A PROMISING ANTIFBROTIC AGENT AGAINST CCL4-INDUCED LIVER FIBROSIS

Objective: Hepatic fibrosis is a wound-healing process in the liver with chronic injury and is characterized by an excess production and deposition of extracellular matrix (ECM) components. Our aim is to investigate the hepatoprotective effects of caffeine against CCL4-induced liver fibrosis in rats and to be compared with the reference standard N-acetylcysteine (NAC).Methods: Rats were divided into 5 groups (n=8), the 1st group served as normal control, the 2nd group received corn oil, the 3rd group is a fibrosis control and the remaining two groups received in addition to CCL4, NAC (150 mg/kg/day) as a reference treatment and caffeine (15 mg/kg/day). At the end of experimental period the following parameters were measured, specific fibrosis biomarkers [hepatic transforming growth factor β1(TGF-β1) and hepatic hydroxyproline (HYP)], liver function biomarkers [serum alanine transaminase (ALT), aspartate transaminase (AST), total bilirubin and albumin], lipid profile [serum triglycerides, total cholesterol, low density lipoprotein cholesterol (LDL-Ch) and high density lipoprotein cholesterol (HDL-Ch)], inflammatory biomarkers [serum tumor necrosis factor alpha (TNF-α), hepatic myeloperoxidase (MPO)], oxidative stress biomarkers [hepatic malondialdehyde (MDA), glutathione (GSH) and catalase (CAT)], relative liver body weight and liver histopathological study.Results: Caffeine significantly improved all the aforementioned biochemical parameters and liver sections obtained from this group showed prominent histopathological improvement.Conclusion: Caffeine hepatoprotective effects may be due to modulation of the fibrous scar formation, Improvement of liver function, Anti-inflammatory and antioxidant potentials

Falls and potential therapeutic interventions among elderly and older adult patients with cancer: a systematic review

Objectives: The aim of this study was to perform a systematic review for previous publications that have assessed the incidence, risk factors, and favorable procedures to prevent and manage falls among cancer survivors of elderly and older adults. Materials: This systematic review was undertook using PubMed, SCOPUS, Web of Science, Medline, and Cochrane Database of clinical studies and systematic reviews to determine the incidence, risk factors, favorable inpatient and outpatient management, and non-pharmacological interventions for falls among elderly and older adult patients with cancer from 2010 to October, 2020. Results: After the comprehensive screening, clinical studies, meta-analysis, systematic reviews, and established guidelines were included in this review. Only 5 clinical studies (3 randomized and 2 single-arm studies), 5 systematic reviews, and 6 established guidelines were considered eligible. The five systematic reviews provide risk factors of falls and the 6 guidelines provide assessment &amp; prevention modalities of falls, however, the 6 clinical studies provide the non-pharmacological intervention for falling among cancer survivors. Many factors associated are demonstrated among wide range of elderly individuals.Earlier falls were reliably listed as an important risk factor of falls in the two inpatient and outpatient environments including both general older people and geriatric cancer populations. Conclusions: This review concludes that the assessment of falls among older individuals with cancer is the most important way for determining who could need additional observation and treatment program. Health professions involving physical therapy and occupational therapy have an important function for promoting health well-being in elderly and older adults with cancer. Keywords: Cancer; falls; elderly; older adults, risk factors, intervention

Hospital Preparedness for Critical Care during COVID-19 Pandemic: Exploratory Cross-sectional Study

AIM: The researchers conducted the study to assess intensive care units (ICUs) preparedness in Cairo University Hospitals to deal efficiently and effectively with COVID-19 upcoming waves. METHODS: An exploratory cross-sectional study was conducted at Cairo University Intensive Care Units 6 pediatric ICUs, and 2 adult ICUs in the period from the end of February to the first week of March, 2020; almost 2 weeks after the appearance of the first case of COVID-19 in Egypt by hand-delivered questionnaire method with one of the ICU staff members who were available and have time to take part in the study. WHO checklist for hospital readiness was used; this checklist based on current knowledge and available evidence on the COVID-19 pandemic for WHO’s Regional Office for the Eastern Mediterranean Region. The WHO has developed the checklist to help hospital managers prepare for COVID-19 patient management by optimizing each hospital’s capacities. The list composed of 10 key components: (1) Leadership and coordination; (2) operational support, logistics and supply management; (3) information; (4) communication; (5) human resources; (6) continuity of essential services and surge capacity; (7) rapid identification; (8) diagnosis; (9) isolation and case management; and (10) infection prevention and control. RESULTS: The overall preparedness in both pediatric and adult ICUs was 54%. Overall, adult ICUs were more prepared than pediatric ICUs, especially in communication; continuity of essential services and surge capacity; rapid identification; diagnosis; isolation; and case management. Both of them were comparable regarding operational support, logistics and supply management; human resources; and infection prevention and control, while information component was lower in both types but reached critical values 10% in adult ones. CONCLUSION: The current study demonstrated the intermediate readiness of ICUs at initial outbreak; further assessment during different phases of pandemic is required. Continues education of HCWs and active communication should be established

Determination of the Optimal Parameters for Self-Healing Efficiency of Encapsulated bacteria in Concrete Simulated Subtropical Climate

Concrete is a remarkable construction material. However, its low tensile strength makes it prone to cracking, which negatively affects its durability. To address this issue, bacterial concrete has been implemented as a self-healing alternative due to its capability to seal microcracks through microbial-induced calcium carbonate precipitation (MICCP). In this study, a bacterial strain (i.e, Bacillus Pseudiformus) was encapsulated through three different methods: encapsulation through hydrogel beads, vacuum impregnation on lightweight aggregates, and attachment to cellulose nanocrystals. Furthermore, three precursor types were used, magnesium acetate, calcium lactate, and sodium lactate were implemented. Compressive strength tests and flexural strength tests were performed on mortar specimens to characterize their mechanical properties. Once the crack was induced, samples were subjected to 28 days of wet/dry cycles in which the corresponding crack width was monitored. At the end of this period, the beams were retested to determine the strength recovery of the specimens. The results showed that the specimen groups in which calcium lactate was added to the cementitious matrix displayed the highest values in compressive strength. In terms of flexural strength, no major difference was found among the specimens. Moreover, the flexural strength recovery of the specimens did not show any significant difference as well. In terms of the healing efficiency, the sample that displayed the best results was the one containing calcium lactate as a precursor along with bacteria and yeast extract encapsulated in hydrogel beads. In addition, scanning electron microscopy (SEM) along with x-ray energy dispersive spectroscopy (EDS) was performed on the cracked specimens to characterize the healing products. Furthermore, a scale study was performed on concrete samples to determine the long-term implications of adding encapsulated bacteria along with calcium lactate and yeast extract in concrete

Caracterización de endemismos mediterráneos en la flora egipcia

The Mediterranean Basin is the world’s second richest hotspot, and one of the most important locations on the planet for endemic taxa. However, there is no available up-to-date list of Mediterranean endemics. Available data are frequently insufficient or outdated. Therefore, this study aimed at delimiting the Mediterranean floristic region in Egypt, screening its Mediterranean endemics, and determining their habitats, life forms, flowering periods, dispersal types and phyto-geographical distribution. From a list of 275 Mediterranean endemic taxa in Egypt compiled from literature, this study reduced it to 57 taxa (including species, subspecies and varieties; 20.7%) belonging to 46 genera and 22 families. Fifteen major habitats harbored Mediterranean endemics in Egypt, with coastal dunes (17 taxa = 29.8%) and non-saline depressions (16 taxa = 28.1%) being the most represented. Moreover, the Mareotis (west) subsector was the richest (46 taxa = 80.7%). The largest number of taxa was recorded in North African sub-region (52 taxa = 91.2%), followed by Eastern (levant) sub-region (36 taxa = 63.2%). Therophytes were the most recorded life form, while ballochory was the most represented dispersal type. In conclusion, it is crucial to shed the light on Mediterranean endemics and provide an up-to-date documented database to help future management plan that support their conservation and sustainable use.La cuenca Mediterránea es el segundo hotspot más rico del mundo y uno de los lugares más importantes del planeta en taxones endémicos. Sin embargo, no existe una lista actualizada de taxones endémicos mediterráneos. Los datos disponibles son frecuentemente insuficientes o están desactualizados. Por tanto, nuestro objetivo fue delimitar la región florística mediterránea en Egipto, seleccionar sus plantas endémicas mediterráneas y determinar sus hábitats, formas de vida, periodos de floración, tipos de dispersión y distribución fitogeográfica. Partiendo de una lista preliminar de 275 taxones endémicos del Mediterráneo presentes en Egipto recopilada de la bibliografía, este estudio redujo ese número a 57 taxones (incluyendo especies, subespecies y variedades; 20.7%) pertenecientes a 46 géneros y 22 familias. Las plantas endémicas mediterráneas de Egipto viven en quince hábitats principales, siendo los más representativos las dunas costeras (17 taxones = 29.8%) y las depresiones no salinas (16 taxones = 28.1%). El subsector Mareotis (al oeste) fue el más rico (46 taxones = 80.7%), mientras que el mayor número de taxones se registró en la subregión del norte de África (52 taxones = 91.2%), seguida de la subregión del este (levante) (36 taxones = 63.2%). Los terófitos fueron la forma vital más registrada y la balocoria el tipo de dispersión más común. En conclusión, es crucial arrojar luz sobre las plantas endémicas del Mediterráneo y proporcionar una base de datos documentada y actualizada que ayude a planificar una gestión futura que promueva su conservación y uso sostenible

Integrated Kinetic Fins for Western Facades in Territories with Low Solar Altitudes

Insufficient daylighting can negatively affect working quality and productivity and increase lighting energy consumption in buildings. Particularly, the western orientation has a non-uniform daylighting distribution, especially at the zone next to the window resulting from the unequal radiation distribution of sunlight. Therefore, this study presents an innovative system known as Integrated Kinetic Fins (IKF), which can respond parametrically to the sun’s movement; to enhance the daylighting distribution during the late working hours for the western façades and decrease the high illuminance daylighting spots near the windows. The study optimizes the fin parameters based on a selected territory; then, the fi angles are automatically controlled. The IKF is applicable in regions with clear skies and low solar altitudes. Finally, a comparison between a traditional kinetic system and the IKF is made, and the results are reported. The system shows an enhancement of daylight distribution during these late hours, where the contrast has been improved by 22% and uniformity has been enhanced by 10%, which consequently contributes to reducing potential glare

Effect of global postural correction exercises on stress urinary incontinence during pregnancy: A randomized controlled trial

Background: One of the many consequences of pregnancy that may negatively affect a woman’s quality of life is stress urinary incontinence caused by activities of daily living especially those associated with increased intraabdominal pressure. Objective: This research aimed to explore the impact of global postural correction exercises on stress urinary incontinence among pregnant women. Participants and Methodology: Forty primigravida female at their third trimester (aged between 26–36 years), with a single fetus, diagnosed with stress urinary incontinence take part in the research. Participants were assigned randomly into two groups: Study group (group A; n = 20) and control group (group B; n = 20). The participants were tested twice, before and after a 12-week period, during which group A received global postural correction exercises in addition to Kegel exercises, while group B performed only Kegel exercises. A perineometer was used to evaluate the change in vaginal squeeze pressure both before and after conducting the study. UDI-6 was utilized to assess changes in incontinence severity symptoms. Results: Findings revealed a significant increase in the mean value of vaginal squeeze pressure (p < .05) in the post-test condition in comparison to the pre-test in both groups A and B. Additionally, there was a main decrease (p < .05) in the mean value of UDI-6 in both groups. Moreover, findings showed a significant negative (inverse) correlation (p < .05) between the difference in vaginal squeeze pressure and the UDI-6 in all patients. Conclusions: Postural correction exercises in addition to Kegel exercises are effective in reducing urine leakage in women with stress urinary incontinence and should be an integral part of the management of such condition