723 research outputs found
A Review on Automated Storage/ Retrieval Systems and Shuttle Based Storage/Retrieval Systems
Automated storage and retrieval systems are warehousing systems that are used for the storage and retrieval of products in both distribution and production environments. Shuttle based storage/retrieval systems are composed of elevators with lifting tables that are attached on a mast, shuttle carriers, buffer positions and the storage racks. It is observed that the shuttle based storage/retrieval systems increases the throughput capacity of the systems compared to automated storage/retrieval systems. Shuttle based storage/retrieval systems is relatively a new technology in automated storage and retrieval systems and usually works with aisle and tier captive shuttles. This new technology is mostly used for mini-load warehouses. The main body of the paper consists of an overview of literature discussing automated storage/retrieval systems and shuttle based storage/retrieval systems
Local Buckling of Stiffened and Unstiffened Elements under Nonuniform Compression
Thin plates subjected to linearly varying inplane compression in one direction may undergo local buckling before failure. An analytical procedure is presented for evaluating the local buckling strength based on which equations for the local buckling stress of unstiffened and stiffened elements are presented
DeepSolarEye: Power Loss Prediction and Weakly Supervised Soiling Localization via Fully Convolutional Networks for Solar Panels
The impact of soiling on solar panels is an important and well-studied
problem in renewable energy sector. In this paper, we present the first
convolutional neural network (CNN) based approach for solar panel soiling and
defect analysis. Our approach takes an RGB image of solar panel and
environmental factors as inputs to predict power loss, soiling localization,
and soiling type. In computer vision, localization is a complex task which
typically requires manually labeled training data such as bounding boxes or
segmentation masks. Our proposed approach consists of specialized four stages
which completely avoids localization ground truth and only needs panel images
with power loss labels for training. The region of impact area obtained from
the predicted localization masks are classified into soiling types using the
webly supervised learning. For improving localization capabilities of CNNs, we
introduce a novel bi-directional input-aware fusion (BiDIAF) block that
reinforces the input at different levels of CNN to learn input-specific feature
maps. Our empirical study shows that BiDIAF improves the power loss prediction
accuracy by about 3% and localization accuracy by about 4%. Our end-to-end
model yields further improvement of about 24% on localization when learned in a
weakly supervised manner. Our approach is generalizable and showed promising
results on web crawled solar panel images. Our system has a frame rate of 22
fps (including all steps) on a NVIDIA TitanX GPU. Additionally, we collected
first of it's kind dataset for solar panel image analysis consisting 45,000+
images.Comment: Accepted for publication at WACV 201
Thermodynamic approach to the dewetting instability in ultrathin films
The fluid dynamics of the classical dewetting instability in ultrathin films
is a non-linear process. However, the physical manifestation of the instability
in terms of characteristic length and time scales can be described by a
linearized form of the initial conditions of the films's dynamics. Alternately,
the thermodynamic approach based on equating the rate of free energy decrease
to the viscous dissipation [de Gennes, C. R. Acad. Paris.v298, 1984] can give
similar information. Here we have evaluated dewetting in the presence of
thermocapillary forces arising from a film-thickness (h) dependent temperature.
Such a situation can be found during pulsed laser melting of ultrathin metal
films where nanoscale effects lead to a local h-dependent temperature. The
thermodynamic approach provides an analytical description of this
thermocapillary dewetting. The results of this approach agree with those from
linear theory and experimental observations provided the minimum value of
viscous dissipation is equated to the rate of free energy decrease. The flow
boundary condition that produces this minimum viscous dissipation is when the
film-substrate tangential stress is zero. The physical implication of this
finding is that the spontaneous dewetting instability follows the path of
minimum rate of energy loss.Comment: 8 pages, 3 figures. Under revie
Recommended from our members
Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase.
Human platelet ALOX12 (hALOX12 or h12-LOX) has been implicated in a variety of human diseases. The present study investigates the active site of hALOX12 to more thoroughly understand how it positions the substrate and achieves nearly perfect regio- and stereospecificities (i.e., 100 ± 5% of the 12(S)-hydroperoxide product), utilizing site-directed mutagenesis. Specifically, we have determined that Arg402 is not as important in substrate binding as previously seen for hALOX15 but that His596 may play a role in anchoring the carboxy terminal of the arachidonic acid during catalysis. In addition, Phe414 creates a π-stacking interaction with a double bond of arachidonic acid (Δ11), and Ala417/Val418 define the bottom of the cavity. However, the influence of Ala417/Val418 on the profile is markedly less for hALOX12 than that seen in hALOX15. Mutating these two residues to larger amino acids (Ala417Ile/Val418Met) only increased the generation of 15-HpETE by 24 ± 2%, but conversely, smaller residues at these positions converted hALOX15 to almost 100% hALOX12 reactivity [Gan et al. (1996) J. Biol. Chem. 271, 25412-25418]. However, we were able to increase 15-HpETE to 46 ± 3% by restricting the width of the active site with the Ala417Ile/Val418Met/Ser594Thr mutation, indicating both depth and width of the active site are important. Finally, residue Leu407 is shown to play a critical role in positioning the substrate correctly, as seen by the increase of 15-HpETE to 21 ± 1% for the single Leu407Gly mutant. These results outline critical differences between the active site requirements of hALOX12 relative to hALOX15 and explain both their product specificity and inhibitory differences
Robust nanopatterning by laser-induced dewetting of metal nanofilms
We have observed nanopattern formation with robust and controllable spatial
ordering by laser-induced dewetting in nanoscopic metal films. Pattern
evolution in Co film of thickness 1\leq h\leq8 nm on SiO_{2} was achieved under
multiple pulse irradiation using a 9 ns pulse laser. Dewetting leads to the
formation of cellular patterns which evolve into polygons that eventually break
up into nanoparticles with monomodal size distribution and short range ordering
in nearest-neighbour spacing R. Spatial ordering was attributed to a
hydrodynamic thin film instability and resulted in a predictable variation of R
and particle diameter D with h. The length scales R and D were found to be
independent of the laser energy. These results suggest that spatially ordered
metal nanoparticles can be robustly assembled by laser-induced dewetting
Inhibitor binding mode and allosteric regulation of Na+-glucose symporters.
Sodium-dependent glucose transporters (SGLTs) exploit sodium gradients to transport sugars across the plasma membrane. Due to their role in renal sugar reabsorption, SGLTs are targets for the treatment of type 2 diabetes. Current therapeutics are phlorizin derivatives that contain a sugar moiety bound to an aromatic aglycon tail. Here, we develop structural models of human SGLT1/2 in complex with inhibitors by combining computational and functional studies. Inhibitors bind with the sugar moiety in the sugar pocket and the aglycon tail in the extracellular vestibule. The binding poses corroborate mutagenesis studies and suggest a partial closure of the outer gate upon binding. The models also reveal a putative Na+ binding site in hSGLT1 whose disruption reduces the transport stoichiometry to the value observed in hSGLT2 and increases inhibition by aglycon tails. Our work demonstrates that subtype selectivity arises from Na+-regulated outer gate closure and a variable region in extracellular loop EL5
Thickness-dependent spontaneous dewetting morphology of ultrathin Ag films
We show here that the morphological pathway of spontaneous dewetting of
ultrathin Ag films on SiO2 under nanosecond laser melting is found to be film
thickness dependent. For films with thickness h between 2 <= h <= 9.5 nm, the
morphology during the intermediate stages of dewetting consisted of
bicontinuous structures. For films 11.5 <= h <= 20 nm, the intermediate stages
consisted of regularly-sized holes. Measurement of the characteristic length
scales for different stages of dewetting as a function of film thickness showed
a systematic increase, which is consistent with the spinodal dewetting
instability over the entire thickness range investigated. This change in
morphology with thickness is consistent with observations made previously for
polymer films [A. Sharma et al, Phys. Rev. Lett., v81, pp3463 (1998); R.
Seemann et al, J. Phys. Cond. Matt., v13, pp4925, (2001)]. Based on the
behavior of free energy curvature that incorporates intermolecular forces, we
have estimated the morphological transition thickness for the intermolecular
forces for Ag on SiO2 . The theory predictions agree well with observations for
Ag. These results show that it is possible to form a variety of complex Ag
nanomorphologies in a consistent manner, which could be useful in optical
applications of Ag surfaces, such as in surface enhanced Raman sensing.Comment: 20 pages, 5 figure
- …