1,215 research outputs found
Finite Schur filtration dimension for modules over an algebra with Schur filtration
Let G be GL_N or SL_N as reductive linear algebraic group over a field k of
positive characteristic p. We prove several results that were previously
established only when N 2^N. Let G act rationally on a finitely
generated commutative k-algebra A. Assume that A as a G-module has a good
filtration or a Schur filtration. Let M be a noetherian A-module with
compatible G action. Then M has finite good/Schur filtration dimension, so that
there are at most finitely many nonzero H^i(G,M). Moreover these H^i(G,M) are
noetherian modules over the ring of invariants A^G. Our main tool is a
resolution involving Schur functors of the ideal of the diagonal in a product
of Grassmannians.Comment: 22 pages; final versio
Pragmatism, Education, and the Problem of Pluralism
The concept of pluralism is of central importance in contemporary moral and political education, where a crucial aim is to promote acceptance of the life choices of others and to teach tolerance towards diversity of values. However, this promotion of pluralism suffers from two immediate difficulties. Firstly, the concept of pluralism has proved somewhat elusive, and it is far from clear that its various uses are congruent. Secondly, there is a long-standing criticism against ethical and political pluralism which maintains that pluralist views are difficult if not impossible to defend without succumbing to dreaded relativism. In this article, I will firstly distinguish an educationally interesting form of pluralism and then, drawing from thinkers in the tradition of philosophical pragmatism, attempt to meet the criticism that such pluralism has no interesting philosophical defense.Peer reviewe
Endoplasmic reticulum stress-induced apoptosis in the development of diabetes: is there a role for adipose tissue and liver?
Diabetes mellitus (DM) is a multifactorial chronic metabolic disease characterized by hyperglycaemia. Several different mechanisms have been implicated in the development of the disease, including endoplasmic reticulum (ER) stress. ER stress is increasingly acknowledged as an important mechanism in the development of DM, not only for β-cell loss but also for insulin resistance. Accumulating evidence suggests that ER stress-induced apoptosis may be an important mode of β-cell loss and therefore important in the development of diabetes. Recent data also suggest a role of ER stress-induced apoptosis in liver and adipose tissue in relation to diabetes, but more extensive studies on human adipocyte and hepatocyte (patho)physiology and ER stress are needed to identify the exact interactions between environmental signals, ER stress and apoptosis in these organs
Quantum Electrodynamics of the Helium Atom
Using singlet S states of the helium atom as an example, I describe precise
calculation of energy levels in few-electron atoms. In particular, a complete
set of effective operators is derived which generates O(m*alpha^6) relativistic
and radiative corrections to the Schr"odinger energy. Average values of these
operators can be calculated using a variational Schr"odinger wave function.Comment: 23 pages, revte
M5-branes from gauge theories on the 5-sphere
We use the 5-sphere partition functions of supersymmetric Yang-Mills theories
to explore the (2,0) superconformal theory on S^5 x S^1. The 5d theories can be
regarded as Scherk-Schwarz reductions of the 6d theory along the circle. In a
special limit, the perturbative partition function takes the form of the
Chern-Simons partition function on S^3. With a simple non-perturbative
completion, it becomes a 6d index which captures the degeneracy of a sector of
BPS states as well as the index version of the vacuum Casimir energy. The
Casimir energy exhibits the N^3 scaling at large N. The large N index for U(N)
gauge group also completely agrees with the supergravity index on AdS_7 x S^4.Comment: 44 pages, 1 figure, v4: ref added, clarified weak/strong coupling
behaviors of large N free energy, minor improvements, version to be published
in JHE
Producing valid statistics when legislation, culture, and medical practices differ for births at or before the threshold of survival: Report of a European workshop
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Downloa
Exploring Curved Superspace
We systematically analyze Riemannian manifolds M that admit rigid
supersymmetry, focusing on four-dimensional N=1 theories with a U(1)_R
symmetry. We find that M admits a single supercharge, if and only if it is a
Hermitian manifold. The supercharge transforms as a scalar on M. We then
consider the restrictions imposed by the presence of additional supercharges.
Two supercharges of opposite R-charge exist on certain fibrations of a
two-torus over a Riemann surface. Upon dimensional reduction, these give rise
to an interesting class of supersymmetric geometries in three dimensions. We
further show that compact manifolds admitting two supercharges of equal
R-charge must be hyperhermitian. Finally, four supercharges imply that M is
locally isometric to M_3 x R, where M_3 is a maximally symmetric space.Comment: 39 pages; minor change
Predatory Bacteria: A Potential Ally against Multidrug-Resistant Gram-Negative Pathogens
Multidrug-resistant (MDR) Gram-negative bacteria have emerged as a serious threat to human and animal health. Bdellovibrio spp. and Micavibrio spp. are Gram-negative bacteria that prey on other Gram-negative bacteria. In this study, the ability of Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus to prey on MDR Gram-negative clinical strains was examined. Although the potential use of predatory bacteria to attack MDR pathogens has been suggested, the data supporting these claims is lacking. By conducting predation experiments we have established that predatory bacteria have the capacity to attack clinical strains of a variety of ß-lactamase-producing, MDR Gram-negative bacteria. Our observations indicate that predatory bacteria maintained their ability to prey on MDR bacteria regardless of their antimicrobial resistance, hence, might be used as therapeutic agents where other antimicrobial drugs fail. © 2013 Kadouri et al
Orientifolds and the Refined Topological String
We study refined topological string theory in the presence of orientifolds by
counting second-quantized BPS states in M-theory. This leads us to propose a
new integrality condition for both refined and unrefined topological strings
when orientifolds are present. We define the SO(2N) refined Chern-Simons theory
which computes refined open string amplitudes for branes wrapping Seifert
three-manifolds. We use the SO(2N) refined Chern-Simons theory to compute new
invariants of torus knots that generalize the Kauffman polynomials. At large N,
the SO(2N) refined Chern-Simons theory on the three-sphere is dual to refined
topological strings on an orientifold of the resolved conifold, generalizing
the Gopakumar-Sinha-Vafa duality. Finally, we use the (2,0) theory to define
and solve refined Chern-Simons theory for all ADE gauge groups
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