Impact of Tributyltin and Triphenyltin on Ivory Shell (Babylonia japonica) Populations

We histopathologically examined gonads and chemically determined organotin compounds in tissues of the ivory shell, Babylonia japonica. Imposex (a superimposition of male-type genital organs on females) occurred in approximately 80–90% of B. japonica specimens that we examined, with the penis and vas deferens both well developed. No oviduct blockage by vas deferens formation was observed. Ovarian spermatogenesis and suppressed ovarian maturation were observed in the females that exhibited imposex, although no histopathological abnormalities were found in males. Tissue distributions of organotin compounds [tributyltin (TBT), triphenyltin (TPhT), and their metabolites] were different for butyltins and phenyltins; a remarkably high accumulation of TBT was observed in the ctenidium, osphradium, and heart, whereas high concentrations of TPhT were detected in the ovary and digestive gland. More than one-third of TBT accumulated in the digestive glands of both males and females, followed by the testis, ctenidium, muscle, and heart tissues in males and in the muscle, ovary, ctenidium, and head tissues (including the central nervous system ganglia) in females. In both males and females, more than half of total TPhT accumulated in the digestive glands, followed by the gonads. The next highest values were in the muscle, ctenidium, and heart tissues in males and in the muscle, oviduct, and head tissues in females. Both TBT and TPhT concentrations in the gonads were positively correlated with penis length in females. Our findings strongly suggest that reproductive failure in adult females accompanied by imposex, possibly induced by TBT and TPhT from antifouling paints, may have caused the marked decline of B. japonica populations in Japan

Prediction of Emerging Technologies Based on Analysis of the U.S. Patent Citation Network

The network of patents connected by citations is an evolving graph, which provides a representation of the innovation process. A patent citing another implies that the cited patent reflects a piece of previously existing knowledge that the citing patent builds upon. A methodology presented here (i) identifies actual clusters of patents: i.e. technological branches, and (ii) gives predictions about the temporal changes of the structure of the clusters. A predictor, called the {citation vector}, is defined for characterizing technological development to show how a patent cited by other patents belongs to various industrial fields. The clustering technique adopted is able to detect the new emerging recombinations, and predicts emerging new technology clusters. The predictive ability of our new method is illustrated on the example of USPTO subcategory 11, Agriculture, Food, Textiles. A cluster of patents is determined based on citation data up to 1991, which shows significant overlap of the class 442 formed at the beginning of 1997. These new tools of predictive analytics could support policy decision making processes in science and technology, and help formulate recommendations for action

Measurement of the cross-section and forward-backward charge asymmetry for the b and c-quark in e+e- annihilation with inclusive muons at sqrt(s) = 58 GeV

We have studied inclusive muon events using all the data collected by the TOPAZ detector at sqrt(s)=58 GeV with an integrated luminosity of 273pb-1. From 1328 inclusive muon events, we measured the ratio R_qq of the cross section for qq-bar production to the total hadronic cross section and forward-backward asymmetry A^q_FB for b and c quarks. The obtained results are R_bb = 0.13+-0.02(stat)+-0.01(syst), R_cc = 0.36+-0.05(stat)+-0.05(syst), A^b_FB = -0.20+-0.16(stat)+-0.01(syst) and A^c_FB = -0.17+-0.14(stat)+-0.02(syst), in fair agreement with a prediction of the standard model.Comment: To be published in EPJ C. 24 pages, 12 figure

K0(K0ˉ)K^0(\bar{K^0}) Production in Two-Photon Processes at TRISTAN

We have carried out an inclusive measurement of $K^0(\bar{K^0})$ production in two-photon processes at TRISTAN. The mean $\sqrt{s}$ was 58 GeV and the integrated luminosity was 199 pb$^{-1}$. High-statistics $K_s$ samples were obtained under such conditions as no-, anti-electron, and remnant-jet tags. The remnant-jet tag, in particular, allowed us, for the first time, to measure the cross sections separately for the resolved-photon and direct processes.Comment: 20 pages, Latex format, 4 figures and KEK-mark included. Table 1 revised. To be published in Phys. Lett.

Measurement of the forward-backward asymmetries for charm- and bottom-quark pair productions at <s><\sqrt{s}>=58GeV with electron tagging

We have measured, with electron tagging, the forward-backward asymmetries of charm- and bottom-quark pair productions at $$=58.01GeV, based on 23,783 hadronic events selected from a data sample of 197pb$^{-1}$ taken with the TOPAZ detector at TRISTAN. The measured forward-backward asymmetries are $A_{FB}^c = -0.49 \pm 0.20(stat.) \pm 0.08 (sys.)$ and $A_{FB}^b = -0.64 \pm 0.35(stat.) \pm 0.13 (sys.)$, which are consistent with the standard model predictions.Comment: 19 pages, Latex format (article), 5 figures included. to be published in Phys. Lett.

Measurement of inclusive electron cross section in γγ\gamma \gamma collisions at TRISTAN

We have studied open charm production in $\gamma \gamma$ collisions with the TOPAZ detector at the TRISTAN $e^{+}e^{-}$ collider. In this study, charm quarks were identified by electrons (and positrons) from semi-leptonic decays of charmed hadrons. The data corresponded to an integrated luminosity of 95.3 pb$^{-1}$ at a center-of-mass energy of 58 GeV. The results are presented as the cross sections of inclusive electron production in $\gamma \gamma$ collisions with an anti-tag condition, as well as the subprocess cross sections, which correspond to resolved-photon processes. The latter were measured by using a sub-sample with remnant jets. A comparison with various theoretical predictions based on direct and resolved-photon processes showed that our data prefer that with relatively large gluon contents in a photon at small $x (x \le 0.1)$, with the next-to-leading order correction, and with a charm-quark mass of 1.3 GeV.Comment: 26 pages, Latex format (article), 5 figures included, to be published in Phys. Lett.

A Measurement of the D∗±D^{*\pm} Cross Section in Two-Photon Processes

We have measured the inclusive $D^{*\pm}$ production cross section in a two-photon collision at the TRISTAN $e^+e^-$ collider. The mean $\sqrt{s}$ of the collider was 57.16 GeV and the integrated luminosity was 150 $pb^{-1}$. The differential cross section ($d\sigma(D^{*\pm})/dP_T$) was obtained in the $P_T$ range between 1.6 and 6.6 GeV and compared with theoretical predictions, such as those involving direct and resolved photon processes.Comment: 8 pages, Latex format (article), figures corrected, published in Phys. Rev. D 50 (1994) 187

Genetic Evidence That the Non-Homologous End-Joining Repair Pathway Is Involved in LINE Retrotransposition

Long interspersed elements (LINEs) are transposable elements that proliferate within eukaryotic genomes, having a large impact on eukaryotic genome evolution. LINEs mobilize via a process called retrotransposition. Although the role of the LINE-encoded protein(s) in retrotransposition has been extensively investigated, the participation of host-encoded factors in retrotransposition remains unclear. To address this issue, we examined retrotransposition frequencies of two structurally different LINEs—zebrafish ZfL2-2 and human L1—in knockout chicken DT40 cell lines deficient in genes involved in the non-homologous end-joining (NHEJ) repair of DNA and in human HeLa cells treated with a drug that inhibits NHEJ. Deficiencies of NHEJ proteins decreased retrotransposition frequencies of both LINEs in these cells, suggesting that NHEJ is involved in LINE retrotransposition. More precise characterization of ZfL2-2 insertions in DT40 cells permitted us to consider the possibility of dual roles for NHEJ in LINE retrotransposition, namely to ensure efficient integration of LINEs and to restrict their full-length formation

Measurement of the branching ratios of the Z0 into heavy quarks

We measure the hadronic branching ratios of the Z0 boson into heavy quarks: Rb=Gamma(Z0->bb)/Gamma(Z0->hadrons) and Rc=Gamma(Z0->cc/Gamma(Z0->hadrons) using a multi-tag technique. The measurement was performed using about 400,000 hadronic Z0 events recorded in the SLD experiment at SLAC between 1996 and 1998. The small and stable SLC beam spot and the CCD-based vertex detector were used to reconstruct bottom and charm hadron decay vertices with high efficiency and purity, which enables us to measure most efficiencies from data. We obtain, Rb=0.21604 +- 0.00098(stat.) +- 0.00073(syst.) -+ 0.00012(Rc) and, Rc= 0.1744 +- 0.0031(stat.) +- 0.0020(syst.) -+ 0.0006(Rb)Comment: 37 pages, 8 figures, to be submitted to Phys. Rev. D version 2: changed title to ratios, used common D production fractions for Rb and Rc and corrected Zgamma interference. Identical to PRD submissio