Free Vibrations of Multilayered Orthotropic Ribbed Cylindrical Shells With Attached Solid Bodies

Kairov, A. S. Free Vibrations of Multilayered Orthotropic Ribbed Cylindrical Shells With Attached Solid Bodies / A. S. Kairov, O. I. Vlasov // Intern. Journ. of mechanical engineering and information technology. – 2018. – Vol. 06, iss. 03. – P. 1772–1777.It is considered the problem of investigation of free vibrations of elastic multilayer orthotropic cylindrical shells made of a composite material with reinforcing ribs and attached solid bodies. A more precise mathematical model of vibrations is developed in the linear equation, which takes into consideration the structural heterogeneity of the shell system. The solution is obtained by the Ritz variational method. The results of a numerical investigation of natural frequencies and free vibration forms of supported cylindrical shells are presented

Calculation of characteristics of hydrodynamical bearing with defined profile of sleeves based on Mathcad

Стаття присвячена проблемам моделювання роботи гідродинамічних опор ковзання в умовах рідинного тертя. Метою роботи є створення автоматизованої системи розрахунку характеристик опор ковзання з втулками довільного (гладкого) профілю. З цією метою розроблені методика і алгоритм вирішення задачі визначення несучої здатності опори ковзання з заданим профілем втулки, а також розроблені рекомендації з отримання раціональних профілів втулок підшипників ковзання. На базі даної методики розроблено систему розрахунку характеристик підшипника ковзання з застосуванням пакета комп'ютерної алгебри Mathcad. Розроблена розрахункова система була використана для пошуку варіантів раціонального профілювання втулки опори ковзання. Були знайдені варіанти профілю втулок опор ковзання, що забезпечують збільшення несучої здатності в порівнянні з опорами, в яких застосовується традиційний (круглий) профіль втулки. Також розроблена система дозволяє проводити експрес-порівняння характеристик опор ковзання з різними профілями втулки.The article is devoted to problems of hydrodynamic simulations of sliding friction in the liquid. The aim is to create an automated system for calculating the characteristics of sliding sleeves with arbitrary (smooth) profile. For this purpose developed a technique and algorithm for determining the carrying capacity of the bearing with arbitrary profile of the sliding sleeve, and developed recommendations for obtaining rational profiles of sleeve of bearing. On the basis of this methodology developed a system for calculating the characteristics of sliding bearing with the use of package of computer algebra Mathcad. Developed calculation system was used to search for variants of rational profiling of sleeve of sliding bearings. Were found variants of profile of sliding sleeves that provide an increase in carrying capacity compared with the supports that use traditional (round) profile of the sleeve. Designed system also allows quick comparison of the characteristics of sliding sleeves with different profiles.Статья посвящена проблемам моделирования работы гидродинамических опор скольжения в условиях жидкостного трения. Целью работы является создание автоматизированной системы расчета характеристик опор скольжения с втулками произвольного (гладкого) профиля. С этой целью разработаны методика и алгоритм решения задачи определения несущей способности опоры скольжения с задаваемым профилем втулки, а также разработаны рекомендации по получению рациональных профилей втулок подшипников скольжения. На базе данной методики разработана система расчета характеристик подшипника скольжения с применением пакета компьютерной алгебры Mathcad. Разработанная расчетная система была использована для поиска вариантов рационального профилирования втулки опоры скольжения. Были найдены варианты профиля втулок опор скольжения, обеспечивающие увеличение несущей способности по сравнению с опорами, в которых применяется традиционный (круглый) профиль втулки. Также разработанная система позволяет проводить экспресс-сравнение характеристик опор скольжения с различными профилями втулки

Собственные колебания конструктивно неоднородных многослойных ортотропных цилиндрических оболочек из композиционных материалов

Каиров, А. С. Собственные колебания конструктивно неоднородных многослойных ортотропных цилиндрических оболочек из композиционных материалов = Free vibrations of constructional non-homogeneous multilayer orthotropic composite cylindrical shells / А. С. Каиров, О. И. Власов, Л. А. Латанская // Фізико-матератичні науки : вісн. ЗНУ. – Запоріжжя : ЗНУ, 2017. – № 2. – С. 57–65.Досліджено вільні коливання пружних багатошарових ортотропних циліндричних оболонок обертання з приєднаними твердими тілами. Розроблена уточнена математична модель коливань, що враховує структурну неоднорідність оболонки. Задача розв’язується в лінійній постановці методом Рітца. Наведено результати розрахунку власних частот і форм вільних коливань оболонкової системи. Виконано порівняння отриманих даних з чисельними результатами для аналогічних задач.Multilayer composite shells constructions are widespread in modern technic. That is why the problems which deal with the constructional non-homogeneous shells oscillation is rather actual. The presence of attached solid bodies, constructional features and composite orthotropic material creates a local inertial inhomogeneity and essential influence on the shells dynamic characteristics. The main aim of this work is to investigate the composite orthotropic material, the direction of reinforcing fibers layers and the attached solid bodies influence on the thin rotation shells oscillation forms and frequencies. The influence of reinforcing fibers orientation on the shells oscillations amplitudes and frequencies has been investigated by means of the new developed calculation method. The solution of this problem has been based on the Ritz method and developed mathematical model usage. The shells stress-strained state has been considered on the base Kirghof-Lyav’s linear hypothesis. According to the OstrogradskyHamiltons principle the problems solution is reduced to the variational equality. In this equality the Lagrange’s functional for the non-homogeneuos shells system consists of the sum of the shell functional and attached solid bodies functions addition. The main problem of the research is simplified by the Kholetsky matrix method usage. Thus the shells system oscillation natural frequencies and forms are calculated by the combination of Kholetsky and Hausholder’s matrix method usage for QR reverse iterations. The obtained frequencies have also been compared with the results of calculation, based on ANSYS program and show good convergence. The numerical results achieved on the base of the developed mathematical model show that the location of orthotropic layers and attached solid bodies sharply influence the thin shells oscillation forms and frequencies. The new dependences and mechanical effects, caused by the shells constructional nonhomogeneity are rather important and should be used in practice.Исследованы свободные колебания упругих многослойных ортотропных цилиндрических оболочек вращения с присоединенными твердыми телами. Разработана уточненная математическая модель колебаний, учитывающая конструктивную неоднородность оболочки. Задача решается в линейной постановке методом Ритца. Приведены результаты расчета собственных частот и форм свободных колебаний оболочечной системы. Выполнено сопоставление полученных данных с численными результатами для аналогичных задач

Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

: O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. 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Knoppers, Global Alliance for Genomics and Health - Regulatory and Ethics Working Group O33 High throughput screening platform of competent sineups: that can enhance translation activities of therapeutic target H. Takahashi, K. R. Nitta, A. Kozhuharova, A. M. Suzuki, H. Sharma, D. Cotella, C. Santoro, S. Zucchelli, S. Gustincich, P. Carninci O34 The undiagnosed diseases network international (UDNI): clinical and laboratory research to meet patient needs J. J. Mulvihill, G. Baynam, W. Gahl, S. C. Groft, K. Kosaki, P. Lasko, B. Melegh, D. Taruscio O36 Performance of computational algorithms in pathogenicity predictions for activating variants in oncogenes versus loss of function mutations in tumor suppressor genes R. Ghosh, S. Plon O37 Identification and electronic health record incorporation of clinically actionable pharmacogenomic variants using prospective targeted sequencing S. Scherer, X. Qin, R. Sanghvi, K. Walker, T. Chiang, D. Muzny, L. Wang, J. Black, E. Boerwinkle, R. 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The Improved Method and Device for Nucleic Acid Isolation Using a High-Salt Gel Electroelution Trap

The success of DNA analytical methods, including long-read sequencing, depends on the availability of high-quality, purified DNA. Previously, we developed a method and device for isolating high-molecular-weight (HMW) DNA for long-read sequencing using a high-salt gel electroelution trap. Here, we present an improved version of this method for purifying nucleic acids with higher yield and purity from even the most difficult biological samples. The proposed method is a significant improvement over the previously published procedure, offering a simple, fast, and efficient solution for isolating not only HMW DNA but also smaller DNA and RNA molecules. The method utilizes vertical gel electrophoresis in two nested, partially overlapping electrophoretic columns. The upper, smaller-diameter column has a thin layer of agarose gel at the bottom and electrophoresis buffer on top and serves to separate nucleic acids from impurities. After the target nucleic acid has been gel-purified on the upper column, a larger-diameter column with a layer of high-salt gel overlaid with electrophoresis buffer is inserted from below. The purified nucleic acid is then electroeluted into the buffer-filled gap between the separating gel and the high-salt gel, where excess counterions from the high-salt gel slow its migration and cause it to accumulate. The proposed vertical purification system outperforms the previously described horizontal system in terms of nucleic acid yield and purity, while also being more user-friendly, scalable, and adaptable to high-throughput workflows. Furthermore, the vertical system allows for the sequential purification of multiple nucleic acid species from the same sample using interchangeable salt-gel columns.Peer reviewe