VITAMIN C AND ITS ROLE IN BODY

Ascorbic acid or Vitamin C is very important in our body because of its antioxidant property. But the main problem; that vitamin C uses is to maintain the stability as well as its drug distribution system. Vitamin C also plays a protective role in diabetes, cancer, heavy metal toxicity or poisoning, etc. Vitamin C is found in many sources present in nature, including tomatoes, broccoli, etc. Many factors in the body, as well as outside the body, affect the content of vitamin C in the body or sources like the season, climate, and pollution affect the content in fruits and vegetables besides sex, age, pregnancy, lactation, etc. affect the vitamin C content in the body. It is extensively used in the common cold, wound healing process, cancer, heavy metal poisoning or toxicity, and even in men's fertility. In this article, we focused on the general aspects: its bioavailability, sources, its toxicity and deficiency, and factors affecting vitamin C level as well as its use in humans. In the last, we conclude, the excess or lack of Vitamin C, both conditions have affected the human body in a significant range. It plays a protective role against many disorders and is required for kids, men, women, and even old-aged patients

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

A Non-Intrusive Method of Face Liveness Detection… [Redacted]

arXiv admin note: This version removed by arXiv administrators as the submitter did not have the right to agree to the license at the time of submissionComment: This paper has been withdrawn as it is the proprietary property of an organization. A revision might or might not be uploaded in the future after further internal reviews and revisions. arXiv admin note: Title redacte

Web-ChatLine: An Innovative Chatting Platform

With the turn of events and improvement in the web, an ever-increasing number of individuals have been choosing online chat platforms for correspondence. Their applications include being used for correspondence over significant distances. Along these lines, the application must both be continuous and multi-stage, and utilized by numerous clients. The online ongoing talking application need not bother with any extra outsider customer program, and visual correspondence could be set up advantageously. The programming instrument utilized to build this application is React.js, Node.js, which has an express structure and an in-memory data set. The text correspondence is moved to and from servers. Furthermore, the information transmission is achieved through highlight point association between servers. Because of the use of the response structure, a virtual space idea is carried out, which improves the presentation over existing applications created utilizing PHP by many times

An FBG-based sensing glove to measure dynamic finger flexure with an angular resolution of 0.1� up to speeds of 80�/s

We demonstrate a fiber Bragg grating (FBG) sensor-based highly accurate instrumented glove that can measure finger flexure with an angular resolution of 0.1�. The sensing unit consists of an FBG that is very sensitive to axial strain induced by the flexing of fingers. The spectral shift of the reflection spectrum of the FBG varies linearly with the joint rotation angle. The sensor offers a very high angular resolution of 0.1� with a very high sensitivity of 18.45 pm/degree. The accuracy evaluated using a mechanical setup and the human hand is 0.13� and 0.67� respectively. This is much better than many other reported sensors. The sensor showed excellent repeatability with a maximum standard deviation of 0.30� and 0.79� on a mechanical setup and the human hand respectively. The results are validated using a pre-calibrated inertial measurement unit (IMU) sensor. The sensor also exhibited much better dynamic response compared to the IMU up to a rotation speed of 80�/s. These results demonstrate that our sensor is a strong potential candidate for the development of high-accuracy instrumented gloves that could be used to monitor the progress in the rehabilitation of stroke survivors. This work focuses on the careful characterization of the sensor to establish it as a sensitive and practical approach. The accuracy, repeatability and dynamic response were evaluated using a motorized mechanical model of a finger joint and also on the hands of two human subjects.by Chandan Kumar Jha, Shivang Agarwal, Arup Lal Chakraborty and Chinmay Shirpurka

Controlling Electronic-Ionic Kinetics via Size Engineering in CsPbBr3 Perovskite Nanocrystals

Owing to the exceptional photovoltaic and optoelectronic properties of metal halide perovskites, they have sparked an intensive interest in the research community. CsPbBr3 perovskite nanocrystals (NCs) have come into sight due to their versatile properties that can be achieved through structural modification. While the prior research on perovskite nanocrystals has focused mainly on tuning optical and electronic properties, the understanding of their electronic-ionic kinetics still remains a significant research gap. In this work, we explore how the size of CsPbBr3 NCs impacts their electronic-ionic properties by using electrochemical impedance spectroscopy (EIS). We systematically tune NC size and investigate the resulting dielectric properties, conductivity, and capacitance. Notably, larger NCs exhibit anomalous behavior similar to that of perovskite polycrystalline thin films in the range of 0.4–0.6 V, indicating strong electronic-ionic coupling. Conversely, smaller NCs display weak electronic-ionic coupling due to ion localization. Additionally, this study sheds light on the electronic-ionic behavior of NCs approaching quantum confinement with a size reduction, suggesting opportunities for defect engineering. Ultimately, this work will pave the way for developing advanced electronic devices utilizing perovskite nanocrystals

Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation

Abstract This review article explores the dynamic field of radiopharmaceuticals, where innovative developments arise from combining radioisotopes and pharmaceuticals, opening up exciting therapeutic possibilities. The in-depth exploration covers targeted drug delivery, delving into passive targeting through enhanced permeability and retention, as well as active targeting using ligand-receptor strategies. The article also discusses stimulus-responsive release systems, which orchestrate controlled release, enhancing precision and therapeutic effectiveness. A significant focus is placed on the crucial role of radiopharmaceuticals in medical imaging and theranostics, highlighting their contribution to diagnostic accuracy and image-guided curative interventions. The review emphasizes safety considerations and strategies for mitigating side effects, providing valuable insights into addressing challenges and achieving precise drug delivery. Looking ahead, the article discusses nanoparticle formulations as cutting-edge innovations in next-generation radiopharmaceuticals, showcasing their potential applications. Real-world examples are presented through case studies, including the use of radiolabelled antibodies for solid tumors, peptide receptor radionuclide therapy for neuroendocrine tumors, and the intricate management of bone metastases. The concluding perspective envisions the future trajectory of radiopharmaceuticals, anticipating a harmonious integration of precision medicine and artificial intelligence. This vision foresees an era where therapeutic precision aligns seamlessly with scientific advancements, ushering in a new epoch marked by the fusion of therapeutic resonance and visionary progress. Graphical Abstrac