A Disseminated Echinococcosis Patient with Five Years Survival from Turkey: A Case Report

Echinococcosis is a parasitic disease characterized by cysts in especially liver and lung. We report a long-term survival of a 44-year-old female patient with disseminated echinococcal disease involving the brain, lung, liver, spleen, kidney, mediastinum, thyroid gland, parotid gland, pancreas, peritoneum, rectus muscle, pararenal area, left thigh, skin and breast tissue from Turkey in 2016

A Travel-Associated Legionella Pneumonia Case Diagnosed with Urinary Antigen Detection Test

A 70-year old man admitted to the hospital with malaise, high fever and cough. He had travelling history to Saudi Arabia 15 days before his admission. Physical findings revealed high fever (39°C), relative bradycardia, cyanosis and hepatomegaly. Thorax examination was normal but chest-radiography showed a pneumonic infiltration in the right lung. Urinary antigen detection test for Legionella pneumophila was positive. The symptoms of the patient were recovered and body temperature was normal on 3rd day of moxifloxacin intravenous 400 mg treatment. The patient has been discharged from hospital on the 10th day of therapy

Adipocyte differentiation defect in mesenchymal stromal cells of patients with malignant infantile osteopetrosis

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Tp–e interval and Tp–e/QT ratio in patients with Human Immunodeficiency Virus

Human Immunodeficiency Virus (HIV) infection and AIDS are known to cause cardiovascular diseases such as premature coronary artery disease, cardiomyopathy, and arrhythmias. Recently, Tp–e interval and Tp–e/QT ratio has been shown as a novel marker of ventricular repolarization. We aimed to evaluate the ventricular repolarization using Tp–e interval and Tp–e/QT ratio in patients with Human Immunodeficiency Virus (HIV) infection. Totally 48 patients with HIV and 60 control subjects were enrolled to the study. Tp–e interval, Tp–e/QT and Tp–e/QTc ratio were measured from the 12-lead electrocardiogram. Tp–e interval, Tp–e/QT ratio and Tp–e/QTc ratio were significantly higher in patients with HIV than control subjects (all p < 0.01). In correlation analysis, there were positive correlation between Tp–e interval and disease duration (r = 0.298, p = 0.048). and inverse correlation between Tp–e interval and CD4 count(r = −0.303, p = 0.036). Our study showed that Tp–e interval, Tp–e/QT and Tp–e/QTc ratios were increased in patients with HIV than control subjects. Keywords: Human Immunodeficiency Virus, Tp–e interval, Tp–e/QT rati

SARcopenia Assessment in Hypertension: The SARAH Study.

© 2022 Wolters Kluwer Health, Inc.Objectives: The aims of the study were to investigate the relationship between sarcopenia and renin-angiotensin system-related disorders and to explore the effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on muscle mass/function and physical performance. Design: This multicenter, cross-sectional study was performed using ISarcoPRM algorithm for the diagnosis of sarcopenia. Results: Of the 2613 participants (mean age = 61.0 ± 9.5 yrs), 1775 (67.9%) were hypertensive. All sarcopenia-related parameters (except chair stand test in males) were worse in hypertensive group than in normotensive group (all P < 0.05). When clinical/potential confounders were adjusted, hypertension was found to be an independent predictor of sarcopenia in males (odds ratio = 2.403 [95% confidence interval = 1.514-3.813]) and females (odds ratio = 1.906 [95% confidence interval = 1.328-2.734], both P < 0.001). After adjusting for confounding factors, we found that all sarcopenia-related parameters (except grip strength and chair stand test in males) were independently/negatively related to hypertension (all P < 0.05). In females, angiotensin-converting enzyme inhibitors users had higher grip strength and chair stand test performance values but had lower anterior thigh muscle thickness and gait speed values, as compared with those using angiotensin II receptor blockers (all P < 0.05). Conclusions: Hypertension was associated with increased risk of sarcopenia at least 2 times. Among antihypertensives, while angiotensin-converting enzyme inhibitors had higher muscle function values, angiotensin II receptor blockers had higher muscle mass and physical performance values only in females