Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

[This corrects the article DOI: 10.1186/s13054-016-1208-6.]

Nutritional habits of female students of the Medical University of Bialystok depending on the socioeconomic situation

Celem pracy była ocena wybranych zwyczajów żywieniowych studentek UMB w zależności od posiadanej sytuacji ekonomiczno-społecznej (SES). Badaniami objęto 251 studentek (18% posiadało sytuację ekonomiczno-społeczną dobrą, 56,5% przeciętną, a 25,5% złą). Niezależnie od sytuacji ekonomiczno-społecznej studentki najczęściej wybierały 4 - posiłkowy model żywienia. Do posiłków najczęściej pomijanych w jadłospisie należały drugie śniadanie i podwieczorek. Sytuacja ekonomiczno-społeczna nie była czynnikiem istotnie różnicującym częstotliwość spożycia wybranych grup produktów spożywczych. Sposób żywienia badanych studentek cechował się niską częstotliwością spożycia m. in. pieczywa razowego, kasz gruboziarnistych, mleka i jego przetworów, ryb, surowych warzyw i owoców.The aim of the study was the estimation of the selected nutritional habits of female students of the Medical University of Bialystok related to the socio-economic situation of families (SES). The investigation included 251 female students (18% of a higher SES, 56.5% students of an average SES and 25.5% students of a lower SES). The highest percentage of female students consumed four meals a day independently on the socio-economic status. Lunch and afternoon snack were the most frequently omitted meals. The socio-economic situation of families did not differ significantly the consumption frequency of selected groups of food products among the studied students. The diets analysed in this study were characterized by low intake of whole meal bread, coarse-grained barley, milk and dairy products, fish, raw vegetables and fruit

Fixed Dose Combination of Perindopril and Indapamide Improves Peripheral Vascular Function in Essential Hypertensive Patients

BACKGROUND: The effect on endothelium-dependent and independent vasodilation of 24-week treatment with a fixed-dose combination of perindopril/indapamide (2/0.625 mg, daily) and atenolol (50 mg, daily), was evaluated in 62 untreated essential hypertensive patients according a double-blind, parallel group, randomized study. METHODS: Brachial artery flow-mediated dilation (FMD), response to sublingual glyceril trinitrate (GTN, 25 microg) and to cold pressor test (CPT) were measured at baseline and after treatments at 12 and 24 weeks, as change in diameter from ultrasound scans by a computerized system. RESULTS: Blood pressure (BP) was (P < 0.001) reduced in both groups, but to a greater (P < 0.01) extent in the perindopril/indapamide group. After 24 weeks, FMD was significantly increased (P < 0.01) by perindopril/indapamide (from 5.0 +/- 2.1 to 6.0 +/- 1.7%) but not by atenolol (from 5.1 +/- 1.8 to 5.5 +/- 1.8%). Improvement in FMD was not statistically related to BP reduction. Response to GTN was also significantly (P < 0.05) increased by perindopril/indapamide (from 6.2 +/- 1.9 to 6.9 +/- 1.7%), but not by atenolol (from 6.1 +/- 2.8 to 6.6 +/- 2.6%). Improvement in GTN response was significantly (P < 0.05) related to BP reduction. Response to CPT was significantly increased (P < 0.001) by perindopril/indapamide after 12 and 24 weeks, whereas atenolol significantly (P < 0.05) improved it only after 24 weeks. CONCLUSIONS: Treatment with perindopril/indapamide improves endothelium-dependent vasodilation in comparison with atenolol. This improvement was observed without significant relations with BP changes, suggesting a pressure-independent effect. Improvement in endothelium-independent and sympathetic-associated vasodilation was also observed. These results suggests that long term therapy with a fixed-dose combination of perindopril/indapamide affords vascular protection in hypertensive patients

Different Effect of Antihypertensive Drugs on Conduit Artery Endothelial Function

o compare the effect of antihypertensive drugs on endothelium-dependent vasodilation in the peripheral conduit arteries of patients with essential hypertension, in a prospective, randomized, parallel group study, endothelial function was assessed in 168 hypertensive patients before and after 6-month treatment with randomly assigned nifedipine GITS ( 30 to 60 mg, n = 28), amlodipine ( 5 to 10 mg, n = 28), atenolol ( 50 to 100 mg, n = 29), nebivolol ( 5 to 10 mg, n = 28), telmisartan ( 80 to 160 mg, n = 29), and perindopril (2 to 4 mg, n = 28). If necessary, hydrochlorothiazide ( 25 mg) was added to each compound. We evaluated brachial artery flow-mediated, endothelium-dependent dilation (high-resolution ultrasound) compared with endothelium-independent response to glyceryl trinitrate (25 mug/s). Brachial artery diameter was measured by automatic computerized analysis. Forty healthy subjects were evaluated as a control group. Oxidative stress production was evaluated by measuring plasma malondialdehyde and plasma lipoperoxides; plasma antioxidant capacity was assessed as ferric-reducing antioxidant power. Hypertensive patients showed a significantly ( P < 0.01) lower flow-mediated dilation (5.2 +/- 1.9%) as compared with healthy control subjects (7.1 +/- 2.6%). Response to glyceryl trinitrate was similar in control subjects and patients. At baseline, blood pressure, diameter, flow-mediated dilation, and response to glyceryl trinitrate were similar in the different treatment groups. All treatments similarly reduced blood pressure, but only perindopril increased flow mediated dilation ( from 5.1 +/- 2 to 6.4 +/- 2.4%; P < 0.01) without modifying the response to glyceryl trinitrate. Perindopril but also telmisartan nifedipine and amlodipine reduced oxidative stress and increased plasma antioxidant capacity. In patients with essential hypertension, ACE inhibitors appear to be the only compounds able to improve conduit artery endothelium-dependent vasodilatio