Evaluation of body image, sexual dysfunctions and quality of life in female patients with generalized anxiety disorder

Objective: This study aimed to compare the patients with GAD in terms of SD, body perception and quality of life with healthy controls. Methods: The study included 41 female patients and 40 healthy female individuals with an aged between 18-50 years, regular sexual life and married. The Arizona Sexual Experiences Scale(ASEX), Short Form 36(SF-36), Body Cathexis Scale(BCS) and Beck Anxiety Inventory were used in the subjects. Patients with chronic illness, comorbid psychiatric, endocrine, alcohol or substance use disorder, drug use that could impair sexual function, pregnant, lactation, were not included in the study. Results: In ASEX, high scores were found in 44% of GAD patients and 17.5% of the control group in terms of SD. Sexual desire, arousal, lubrication, and orgasm scores of ASEX correlated with the body dissatisfaction in GAD patients. Physical function, general health status, mental health scores of SF-36 were found lower in the GAD group. Discussion: As a result of these findings, it can be suggested that sexual function, body image and quality of life are negatively affected in GAD patients and that deterioration of them should be questioned as well as symptomatic relief in patients' follow-up and treatment

Isolation, characterization and synthesis of taxol units and a novel manganese(III)acetate mediated synthesis of biaryls

Ph.D. - Doctoral Progra

Chemoenzymatic synthesis of 2-bromo-6-hydroxy-3-methoxy-2-cyclohexen-1-one

A chemoenzymatic synthesis of 2-bromo-6-hydroxy-3-methoxy-2-cyclohexen-1- one starting from cyclohexane-1,3-dione is reported. Manganese(III) acetate-mediated acetoxylation followed by the enzyme-mediated hydrolysis of ??-acetoxy enone affords hydroxy-enone 5 and acetoxy enone 4 with high enantiomeric excesses in good yields. © TÜBİTAK

How Do Health Anxiety, Somatosensory Amplification, and Depression Levels Relate to Non-cyclical Mastalgia? A Case-Control Study

Symptoms that are not completely explicable, such as mastalgia, might cause individuals to experience more apprehension regarding health and to visit doctors more frequently. No study has been found in the literature that assessed the level of somatosensory amplification of patients with mastalgia. This study is intended to assess the levels of somatosensory amplification of patients who complain of mastalgia and to compare them to a healthy control group. Forty patients with the diagnosis of non-cyclical mastalgia and 41 voluntary controls were incorporated in the study. All patients participating in the study were assessed using the Somatosensory Amplification Scale (SSAS), Health Anxiety Inventory (HAI), Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI). The scores of SSAS, HAI, BAI, and BDI for the patient group were higher than those for the control group. Upon a simple regression analysis, the effect of education duration in mastalgia group on HAI was 12.4%, the effect of anxiety level on SSAS was 28%, and that of the depression level on HAI was 10.8%. Patients with mastalgia exhibited higher levels of somatosensory amplification, depression, anxiety, and health anxiety than the control group. The idiopathic symptoms might cause individuals to develop a higher level of somatosensory amplification and to perceive bodily symptoms more severely. Furthermore, such symptoms might further produce anxiety and depressive symptoms due to the higher perception by the individuals with apprehension related to their health