549 research outputs found

    Comparison of hyperspectral versus traditional field measurements of fractional ground cover in the Australian arid zone

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    Published: 28 November 2019The collection of high-quality field measurements of ground cover is critical for calibration and validation of fractional ground cover maps derived from satellite imagery. Field-based hyperspectral ground cover sampling is a potential alternative to traditional in situ techniques. This study aimed to develop an effective sampling design for spectral ground cover surveys in order to estimate fractional ground cover in the Australian arid zone. To meet this aim, we addressed two key objectives: (1) Determining how spectral surveys and traditional step-point sampling compare when conducted at the same spatial scale and (2) comparing these two methods to current Australian satellite-derived fractional cover products. Across seven arid, sparsely vegetated survey sites, six 500-m transects were established. Ground cover reflectance was recorded taking continuous hyperspectral readings along each transect while step-point surveys were conducted along the same transects. Both measures of ground cover were converted into proportions of photosynthetic vegetation, non-photosynthetic vegetation, and bare soil for each site. Comparisons were made of the proportions of photosynthetic vegetation, non-photosynthetic vegetation, and bare soil derived from both in situ methods as well as MODIS and Landsat fractional cover products. We found strong correlations between fractional cover derived from hyperspectral and step-point sampling conducted at the same spatial scale at our survey sites. Comparison of the in situ measurements and image-derived fractional cover products showed that overall, the Landsat product was strongly related to both in situ methods for non-photosynthetic vegetation and bare soil whereas the MODIS product was strongly correlated with both in situ methods for photosynthetic vegetation. This study demonstrates the potential of the spectral transect method, both in its ability to produce results comparable to the traditional transect measures, but also in its improved objectivity and relative logistic ease. Future efforts should be made to include spectral ground cover sampling as part of Australia’s plan to produce calibration and validation datasets for remotely sensed products.Claire Fisk, Kenneth D. Clarke and Megan M. Lewi

    Synthetic spectra of BeH, BeD and BeT for emission modeling in JET plasmas

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    A theoretical model for isotopologues of beryllium monohydride, BeH, BeD and BeT, A (2)Pi to X (2)Sigma(+) visible and X (2)Sigma(+) to X (2)Sigma(+) infrared rovibronic spectra is presented. The MARVEL procedure is used to compute empirical rovibronic energy levels for BeH, BeD and BeT, using experimental transition data for the X (2)Sigma(+), A (2)Pi, and C (2)Sigma(+) states. The energy levels from these calculations are then used in the program Duo to produce a potential energy curve for the ground state, X (2)Sigma, and to fit an improved potential energy curve for the first excited state, A (2)Pi, including a spin-orbit coupling term, a A-doubling state to state (A-X states) coupling term, and Born-Oppenheimer breakdown terms for both curves. These, along with a previously computed ab initio dipole curve for the X and A states are used to generate vibrational-rotational wavefunctions, transition energies and A-values. From the transition energies and Einstein coefficients, accurate assigned synthetic spectra for BeH and its isotopologues are obtained at given rotational and vibrational temperatures. The BeH spectrum is compared with a high resolution hollow-cathode lamp spectrum and the BeD spectrum with high resolution spectra from JET giving effective vibrational and rotational temperatures. Full A-X and X-X line lists are given for BeH, BeD and BeT and provided as supplementary data on the ExoMol website.EURATOM 633053RCUK Energy Programme P012450/

    Pseudo Goldstone Bosons Phenomenology in Minimal Walking Technicolor

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    We construct the non-linear realized Lagrangian for the Goldstone Bosons associated to the breaking pattern of SU(4) to SO(4). This pattern is expected to occur in any Technicolor extension of the standard model featuring two Dirac fermions transforming according to real representations of the underlying gauge group. We concentrate on the Minimal Walking Technicolor quantum number assignments with respect to the standard model symmetries. We demonstrate that for, any choice of the quantum numbers, consistent with gauge and Witten anomalies the spectrum of the pseudo Goldstone Bosons contains electrically doubly charged states which can be discovered at the Large Hadron Collider.Comment: 25 pages, 5 figure

    Hyaluronic Acid Binding Sperm Selection for assisted reproduction treatment (HABSelect): Study protocol for a multicentre randomised controlled trial

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    © Published by the BMJ Publishing Group Limited.Introduction The selection of a sperm with good genomic integrity is an important consideration for improving intracytoplasmic sperm injection (ICSI) outcome. Current convention selects sperm by vigour and morphology, but preliminary evidence suggests selection based on hyaluronic acid binding may be beneficial. The aim of the Hyaluronic Acid Binding Sperm Selection (HABSelect) trial is to determine the efficacy of hyaluronic acid (HA)-selection of sperm versus conventionally selected sperm prior to ICSI on live birth rate (LBR). The mechanistic aim is to assess whether and how the chromatin state of HA-selected sperm corresponds with clinical outcomes - clinical pregnancy rate (CPR), LBR and pregnancy loss (PL). Methods and analysis Couples attending UK Centres will be approached, eligibility screening performed and informed consent sought. Randomisation will occur within 24 hours prior to ICSI treatment. Participants will be randomly allocated 1:1 to the intervention arm (physiological intracytoplasmic sperm injection, PICSI) versus the control arm using conventional methods (ICSI). The primary clinical outcome is LBR ≄37 weeks' gestation with the mechanistic study determining LBR's relationship with sperm DNA integrity. Secondary outcomes will determine this for CPR and PL. Only embryologists performing the procedure will be aware of the treatment allocation. Steps will be taken to militate against biases arising from embryologists being non-blinded. Randomisation will use a minimisation algorithm to balance for key prognostic variables. The trial is powered to detect a 5% difference (24-29%: p=0.05) in LBR ≄37 weeks' gestation. Selected residual sperm samples will be tested by one or more assays of DNA integrity. Ethics and dissemination HABSelect is a UK NIHR-EME funded study (reg no 11/14/34; IRAS REF. 13/YH/0162). The trial was designed in partnership with patient and public involvement to help maximise patient benefits. Trial findings will be reported as per CONSORT guidelines and will be made available in lay language via the trial web site (http://www.habselect.org.uk/). Trial registration number ISRCTN99214271; Pre-results

    Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

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    Altres ajuts: This work has also been supported by a "MaratĂł TV3" grant (20141210 to J.F. and 044412 to R.B.).Trisomy 21 (T21) causes Down syndrome (DS), affecting immune and neurological function by ill-defined mechanisms. Here we report a large metabolomics study of plasma and cerebrospinal fluid, showing in independent cohorts that people with DS produce elevated levels of kynurenine and quinolinic acid, two tryptophan catabolites with potent immunosuppressive and neurotoxic properties, respectively. Immune cells of people with DS overexpress IDO1, the rate-limiting enzyme in the kynurenine pathway (KP) and a known interferon (IFN)-stimulated gene. Furthermore, the levels of IFN-inducible cytokines positively correlate with KP dysregulation. Using metabolic tracing assays, we show that overexpression of IFN receptors encoded on chromosome 21 contribute to enhanced IFN stimulation, thereby causing IDO1 overexpression and kynurenine overproduction in cells with T21. Finally, a mouse model of DS carrying triplication of IFN receptors exhibits KP dysregulation. Together, our results reveal a mechanism by which T21 could drive immunosuppression and neurotoxicity in DS

    Constraints on the Nucleon Strange Form Factors at Q^2 ~ 0.1 GeV^2

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    We report the most precise measurement to date of a parity-violating asymmetry in elastic electron-proton scattering. The measurement was carried out with a beam energy of 3.03 GeV and a scattering angle =6 degrees, with the result A_PV = -1.14 +/- 0.24 (stat) +/- 0.06 (syst) parts per million. From this we extract, at Q^2 = 0.099 GeV^2, the strange form factor combination G_E^s + 0.080 G_M^s = 0.030 +/- 0.025 (stat) +/- 0.006 (syst) +/- 0.012 (FF) where the first two errors are experimental and the last error is due to the uncertainty in the neutron electromagnetic form factor. This result significantly improves current knowledge of G_E^s and G_M^s at Q^2 ~0.1 GeV^2. A consistent picture emerges when several measurements at about the same Q^2 value are combined: G_E^s is consistent with zero while G_M^s prefers positive values though G_E^s=G_M^s=0 is compatible with the data at 95% C.L.Comment: minor wording changes for clarity, updated references, dropped one figure to improve focu

    The composition of the protosolar disk and the formation conditions for comets

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    Conditions in the protosolar nebula have left their mark in the composition of cometary volatiles, thought to be some of the most pristine material in the solar system. Cometary compositions represent the end point of processing that began in the parent molecular cloud core and continued through the collapse of that core to form the protosun and the solar nebula, and finally during the evolution of the solar nebula itself as the cometary bodies were accreting. Disentangling the effects of the various epochs on the final composition of a comet is complicated. But comets are not the only source of information about the solar nebula. Protostellar disks around young stars similar to the protosun provide a way of investigating the evolution of disks similar to the solar nebula while they are in the process of evolving to form their own solar systems. In this way we can learn about the physical and chemical conditions under which comets formed, and about the types of dynamical processing that shaped the solar system we see today. This paper summarizes some recent contributions to our understanding of both cometary volatiles and the composition, structure and evolution of protostellar disks.Comment: To appear in Space Science Reviews. The final publication is available at Springer via http://dx.doi.org/10.1007/s11214-015-0167-
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