A fuzzy approach for unequal workers-task assignment with heptagonal fuzzy numbers

The problem of assigning n tasks to n workers with minimum assignment cost often arises in many practical applications. In real life, the cost of assignment may not be certain and also the number of tasks may not be always equal to the number of workers and an unbalanced situation may arise often. In this paper, the representation of the Heptagonal fuzzy number(HFN) and its arithmetic operations are reviewed and a fuzzy approach called as fuzzy row penalty method is extended within the context of Heptagonal fuzzy numbers to deal with the unbalanced Fuzzy Assignment Problems. The cost of assignment is represented by Heptagonal fuzzy numbers which are capable of incorporating the degree of satisfaction about the assignment cost. So the use of HFN is more suitable. The proposed method overcomes the limitations of existing methods and it is illustrated through numerical example

Prospects of III-Vs for Logic Applications

The increasing challenges for further scaling down of Si CMOS require the study of alternative channel materials. This paper highlights the significance of III-V compound semiconductor materials in order to face the looming fate of Si CMOS technology. The potential advantages of using III-Vs as channel materials for future III-V CMOS is its outstanding transport properties that have been widely accepted in high frequency RF applications. However, many significant challenges in front of III-V digital technology needs to be overcome before III-V CMOS becomes feasible for next generation high speed and low power logic applications. But it may be that this situation is changing given recent progress in the fabrication of high-mobility III-Vs based heterostructure electronic devices for logic applications to fulfill the needs towards the everyday evolving III-V CMOS technology. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/2778

An ammocoete larva of Entosphenus lamottenii (Lesueur) with an accessory tail

This article does not have an abstract

Serum 25-Hydroxy Vitamin D Levels in Patients with Polymorphic Light Eruptions: A Case-control Study

Introduction: Polymorphic Light Eruptions (PMLE) are immune mediated dermal maculopapular eruptions that occurs after sun exposure. Vitamin D deficiency has been gaining attention in many dermatological diseases of varied pathologies. Research studies on vitamin D levels in PMLE are lacking despite it being an immuno modulator. Aim: To estimate the levels of serum 25-OH Vitamin D among patients with PMLE disease and also to compare its level with healthy controls Materials and Methods: A case-control study was conducted during January 2022 to June 2022 in Melmaruvathur Adhiparasakthi Institute of Medical Sciences and Research Hospital, Tamil Nadu, India. Total 80 participants (40 patients with PMLE eruptions and 40 normal healthy volunteers), of both sexes aged between 40-60 years were included. Serum 25-OH Vitamin D levels were estimated for participants and the data obtained were analysed by using Student’s t-test and Chi-square test as tests for significance and Odds ratio by logistic regression as test for outcome association. Results: Amongst the total 80 participants, 40 in each case and control group, mean age in case group was 50.08±5.21 years and in control group was 49.80±5.68 years. The results of the study showed significantly reduced serum 25-OH vitamin D levels (30.13±7.39 ng/mL) among cases compared to controls (34.50±6.05 ng/mL) (p=0.005). It further showed significant positive B (0.160) slope for sunlight exposure and significant negative B (-0.556) slope for serum vitamin D levels with odds of occurrence to PMLE disease state increases by 17.4% for every unit increase in sunlight Ultraviolet (UV) exposure {Odds ratio: 1.174 (C.I: 1.088-1.266)} and decreases by 42.6% for every unit increase in Vitamin D levels {Odds ratio: 0.574 (C.I: 0.446-0.738)}. Conclusion: Most PMLE patients were found to have significantly lower Vitamin D levels with majority in the pre- deficient zones. These findings suggest Vitamin D could be a cost effective alternative prospect in both PMLE diagnostics and therapeutics in future after thorough trial validations

Chemical approaches to the re-structuring of proteins

Methodologies for protein re-structuring have been developed enabling site specific side chain modification to either coded or non-coded residues. Procedures for the modification of the protein profile by attachment of either pendants or structural motifs have been delineated. Selectivity has been demonstrated on the basis of modulation of the -CH2- spacer, which interposes the functional group and the peptide backbone

The osteoporosis treatment gap in patients at risk of fracture in European primary care : a multi-country cross-sectional observational study

Summary This study in 8 countries across Europe found that about 75% of elderly women seen in primary care who were at high risk of osteoporosis-related fractures were not receiving appropriate medication. Lack of osteoporosis diagnosis appeared to be an important contributing factor. Introduction Treatment rates in osteoporosis are documented to be low. We wished to assess the osteoporosis treatment gap in women ≥ 70 years in routine primary care across Europe. Methods This cross-sectional observational study in 8 European countries collected data from women 70 years or older visiting their general practitioner. The primary outcome was treatment gap: the proportion who were not receiving any osteoporosis medication among those at increased risk of fragility fracture (using history of fracture, 10-year probability of fracture above country-specific Fracture Risk Assessment Tool [FRAX] thresholds, T-score ≤ − 2.5). Results Median 10-year probability of fracture (without bone mineral density [BMD]) for the 3798 enrolled patients was 7.2% (hip) and 16.6% (major osteoporotic). Overall, 2077 women (55%) met one or more definitions for increased risk of fragility fracture: 1200 had a prior fracture, 1814 exceeded the FRAX threshold, and 318 had a T-score ≤ − 2.5 (only 944 received a dual-energy x-ray absorptiometry [DXA] scan). In those at increased fracture risk, the median 10-year probability of hip and major osteoporotic fracture was 11.2% and 22.8%, vs 4.1% and 11.5% in those deemed not at risk. An osteoporosis diagnosis was recorded in 804 patients (21.2%); most (79.7%) of these were at increased fracture risk. The treatment gap was 74.6%, varying from 53% in Ireland to 91% in Germany. Patients with an osteoporosis diagnosis were found to have a lower treatment gap than those without a diagnosis, with an absolute reduction of 63%. Conclusions There is a large treatment gap in women aged ≥ 70 years at increased risk of fragility fracture in routine primary care across Europe. The gap appears to be related to a low rate of osteoporosis diagnosis

Wide dynamic range tranimpedance amplifier using peaking capacitance technique for high speed optical wireless communication system

In the high speed optical communication, the requirement of designing the new optical transceivers is quite challenging due to the bandwidth, noise and environmental conditions for designing the optical transceivers. The optical transceivers design is also challenging because of weak optical signal at the frond-end amplifier. In this paper, the optical transceivers via an optical preamplifier for optical wireless communication is designed. The designed system offers the improved performance in terms of bandwidth and gain compared to existing optical transceivers. It is defined that using the designed system, a high bandwidth of 2.114GHz at 29.72dB gain is achieved. The designed optical transceiver provides the bandwidth enhancement utilizing the peaking inductor and capacitor

Expert consensus on the management of acne in India

Acne, a common cutaneous disorder, is estimated to affect a significant proportion of the population at some point in their lifetime. It is one of the most common presentations reported in dermatological consultations in India. Treatment options for acne include topical, oral and procedural therapies. Patients with mild acne can be treated with topical therapies; however, those with moderate to severe acne require systemic cure. Oral antibiotic treatment, hormonal therapies and isotretinoin are the mainstay systemic therapies for acne. Additionally, procedural therapeutic modalities in dermatology include chemical peels, laser therapy, micro needling techniques, to name a few. Scientific advances are continually improving knowledge of acne and contributing to refinement of treatment options. Hence, it is vital for clinicians to regularly update their clinical practice patterns to reflect current standard. An experts’ panel discussion involving dermatologists from across India was conducted, to outline a practical approach for the management of acne. The present consensus document focuses on the assessment of acne, use of topical treatments, role of systemic therapy and procedures in treating acne and post-inflammatory hyperpigmentation. It also emphasizes the role of patient education and counselling on prophylactic and treatment strategies in acne management