To lead or not to lead : analysis of the sprint in track cycling

This paper uses a statistical analysis of match sprint outcomes to guide tactical decisions in this highly tactical contest and to provide competitors and coaches with a potential, marginal gain. Logistic regression models are developed to predict the probability of the leading rider winning at different points of the race, based on how the race proceeds up to each point. Key tactics are successfully identified from the models, including how the leading rider might hold the lead and how the following rider might optimise overtaking

The role of domiciliary nebulizers in managing patients with severe COPD

AbstractThe difficulty of assessing nebulizer responses in chronic obstructive pulmonary disease (COPD) has been demonstrated before. This study aims to re-examine both the role of domiciliary nebulizers in COPD and also bronchodilator (BD) assessment in individuals. In a double-blind, randomized, cross-over trial, 19 stable patients with severe COPD were given the following medication 6-hourly for 2-week periods: (1) nebulized salbutamol 2·5 mg with ipratropium 0·5 mg and placebo inhalers (MDI) with spacer; (2) placebo nebules and inhaled salbutamol 400 μ g with ipratropium 80 μ g via MDI with spacer; (3) inhaled salbutamol 400 μ g with ipratropium 80 μ g via MDI with spacer (but no placebo nebulized drugs).Both nebulized and MDI drugs produced highly significant improvements in forced expiratory volume in 1 sec (FEV1), forced vital capacity (FVC), specific airways conductance, 6-min walking distance (6MWD) and residual volume. There were no significant differences between BD responses obtained after active nebulized and active MDI BDs. From the diary cards, 2 weeks of active nebulized BDs produced a slightly higher median peak expiratory flow (PEF) than active MDI BDs (236 and 219 l m−1, respectively, P=0·01) and slightly less extra inhaler use (0·8 and 1·1 puffs, respectively, P<0·05) but no significant difference in dyspnoea or quality of life (QOL) scores. There were significant correlations between domiciliary PEF and acute BD-induced changes in FVC and 6MWD, and also between domiciliary dyspnoea scores and acute changes in both total lung capacity and 6MWD.In conclusion, nebulized medication conferred little clinical advantage over the regular use of inhalers with spacers in this group of patients with severe COPD. However, acute changes in total lung capacity, FVC and 6MWD may be useful predictors of the longer-term effects of nebulized BDs in individual patients

A través de los ojos del niño: Una intervención avanzada de coordinación de parentalidad para las familias con alto conflicto posterior al divorcio

This article describes and outlines a brief intervention designed to help bring high conflict divorcing parents back together in solidarity with the express purpose of bettering the family climate for their shared child or children. “Through the Eyes of the Child”, a six-session intervention based on principles of a Focused Coparenting Consultation model, was designed to be implemented during parenting coordination work with high conflict couples, either as an enhancement of the work itself, or as an adjunct intervention that may be offered by another professional concurrently with Phase II of the parenting coordination work. Rationale for and components of the intervention are described, and commentary is offered regarding skills needed to aptly deliver the intervention. Este artículo describe y detalla una breve intervención diseñada para ayudar a que los progenitores en un divorcio con alto grado de conflicto se unan en solidaridad con el propósito de mejorar el clima familiar para sus hijos o hijas en común. «A través de los ojos del niño» es una intervención de seis sesiones basada en los principios del modelo denominado «Focused Coparenting Consultation» (consulta centrada en la coparentalidad). Se diseñó para ser implementada durante la coordinación de parentalidad, ya sea como un potenciador del trabajo en sí o como una intervención paralela que puede ofrecer otro profesional en la fase II de un proceso de coordinación de parentalidad. En el artículo se describen la justificación y los componentes de esta intervención y se comentan las habilidades necesarias para poder implementar esta intervención de manera adecuada.

Bayesian estimation for selective trace gas detection

We present a Bayesian estimation analysis for a particular trace gas detection technique with species separation provided by differential diffusion. The proposed method collects a sample containing multiple gas species into a common volume, and then allows it to diffuse across a linear array of optical absorption detectors, using, for example, high-finesse Fabry-Perot cavities. The estimation procedure assumes that all gas parameters (e.g. diffusion constants, optical cross sections) are known except for the number population of each species, which are determined from the time-of-flight absorption profiles in each detector

Harmonic Love wave devices for biosensing applications

Simultaneous operation of a Love wave biosensor at the fundamental frequency and third harmonic, including the optimisation of IDT metallisation thickness, has been investigated. Data is presented showing a sequence of deposition and removal of a model mass layer of palmitoyl-oleoyl-sn-glycerophosphocholine (POPC) vesicles while frequency hopping between 110 and 330 MH

Nanotechnology: current concepts in orthopaedic surgery and future directions.

Nanotechnology is the study, production and controlled manipulation of materials with a grain size \u3c 100 nm. At this level, the laws of classical mechanics fall away and those of quantum mechanics take over, resulting in unique behaviour of matter in terms of melting point, conductivity and reactivity. Additionally, and likely more significant, as grain size decreases, the ratio of surface area to volume drastically increases, allowing for greater interaction between implants and the surrounding cellular environment. This favourable increase in surface area plays an important role in mesenchymal cell differentiation and ultimately bone-implant interactions. Basic science and translational research have revealed important potential applications for nanotechnology in orthopaedic surgery, particularly with regard to improving the interaction between implants and host bone. Nanophase materials more closely match the architecture of native trabecular bone, thereby greatly improving the osseo-integration of orthopaedic implants. Nanophase-coated prostheses can also reduce bacterial adhesion more than conventionally surfaced prostheses. Nanophase selenium has shown great promise when used for tumour reconstructions, as has nanophase silver in the management of traumatic wounds. Nanophase silver may significantly improve healing of peripheral nerve injuries, and nanophase gold has powerful anti-inflammatory effects on tendon inflammation. Considerable advances must be made in our understanding of the potential health risks of production, implantation and wear patterns of nanophase devices before they are approved for clinical use. Their potential, however, is considerable, and is likely to benefit us all in the future. Cite this article: Bone Joint J 2014; 96-B: 569-73

Prospectus, September 21, 1994

https://spark.parkland.edu/prospectus_1994/1013/thumbnail.jp

Associations between e-cigarette access and smoking and drinking behaviours in teenagers

Background: Public health concerns regarding e-cigarettes and debate on appropriate regulatory responses are focusing on the need to prevent child access to these devices. However, little is currently known about the characteristics of those young people that are accessing e-cigarettes. Methods: Using a cross-sectional survey of 14-17 year old school students in North West England (n = 16,193) we examined associations between e-cigarette access and demographics, conventional smoking behaviours, alcohol consumption, and methods of accessing cigarettes and alcohol. Access to e-cigarettes was identified through a question asking students if they had ever tried or purchased e-cigarettes. Results: One in five participants reported having accessed e-cigarettes (19.2%). Prevalence was highest among\ud smokers (rising to 75.8% in those smoking >5 per day), although 15.8% of teenagers that had accessed e-cigarettes had never smoked conventional cigarettes (v.13.6% being ex-smokers). E-cigarette access was independently associated with male gender, having parents/guardians that smoke and students’ alcohol use. Compared with non-drinkers, teenagers that drank alcohol at least weekly and binge drank were more likely to have accessed e-cigarettes (adjusted odds ratio [AOR] 1.89, P < 0.001), with this association particularly strong among never-smokers (AOR 4.59, P < 0.001). Among drinkers, e-cigarette access was related to: drinking to get drunk, alcohol-related violence, consumption of spirits; self-purchase of alcohol from shops or supermarkets; and accessing alcohol by recruiting adult proxy purchasers outside shops. Conclusions: There is an urgent need for controls on the promotion and sale of e-cigarettes to children. Findings suggest that e-cigarettes are being accessed by teenagers more for experimentation than smoking cessation. Those most likely to access e-cigarettes may already be familiar with illicit methods of accessing age-restricted substances

You’re the emotional one: the role of perspective for emotion processing in reading comprehension

Two experiments were conducted to explore whether perspective influences the way readers engage with and process emotional information while reading. Texts presenting characters in an emotional situation from either a personal or an onlooker perspective were presented and reading times were measured for each sentence. Participants also provided emotional self-ratings after reading. In the first experiment, positive texts were processed with greater ease, especially when readers experienced the texts from a personal perspective. In Experiment 2, an emotional match/mismatch was inserted so that a final explicit emotion word either matched or mismatched the emotional valence of the text. Mismatch effects were stronger and more consistent for the personal perspective. The two experiments provide evidence that the perspective of the reader can influence emotion processing. Processing of emotional information was easier for the personal perspective, and readers were more sensitive to inconsistent emotional information from that perspective