Electrodeposition of Metals in Microgravity Conditions

Metal electrodeposition may introduce various morphological variations depending on the electrolytic conditions including cell configurations. For liquid electrolytes, a precise study of these deposits may be complicated by convective motion due to buoyancy. Zero-gravity (0-G) condition provided by drop shaft or parabolic flight gives a straightforward mean to avoid this effect: we present here 0-G electrodeposition experiments, which we compare to ground experiments (1-G). Two electrochemical systems were studied by laser interferometry, allowing to measure the concentration variations in the electrolyte: copper deposition from copper sulfate aqueous solution and lithium deposition from an ionic liquid containing LiTFSI. For copper, concentration variations were in good agreement with theory. For lithium, an apparent induction time was observed for the concentration evolution at 1-G: due to this induction time and to the low diffusion coefficient in ionic liquid, the concentration variations were hardly measurable in the parabolic flight 0-G periods of 20 seconds

Statistics of reduced words in locally free and braid groups: Abstract studies and application to ballistic growth model

We study numerically and analytically the average length of reduced (primitive) words in so-called locally free and braid groups. We consider the situations when the letters in the initial words are drawn either without or with correlations. In the latter case we show that the average length of the reduced word can be increased or lowered depending on the type of correlation. The ideas developed are used for analytical computation of the average number of peaks of the surface appearing in some specific ballistic growth modelComment: 29 pages, LaTeX, 7 separated Postscript figures (available on request), submitted to J. Phys. (A): Math. Ge

Tangling clustering of inertial particles in stably stratified turbulence

We have predicted theoretically and detected in laboratory experiments a new type of particle clustering (tangling clustering of inertial particles) in a stably stratified turbulence with imposed mean vertical temperature gradient. In this stratified turbulence a spatial distribution of the mean particle number density is nonuniform due to the phenomenon of turbulent thermal diffusion, that results in formation of a gradient of the mean particle number density, \nabla N, and generation of fluctuations of the particle number density by tangling of the gradient, \nabla N, by velocity fluctuations. The mean temperature gradient, \nabla T, produces the temperature fluctuations by tangling of the gradient, \nabla T, by velocity fluctuations. These fluctuations increase the rate of formation of the particle clusters in small scales. In the laboratory stratified turbulence this tangling clustering is much more effective than a pure inertial clustering that has been observed in isothermal turbulence. In particular, in our experiments in oscillating grid isothermal turbulence in air without imposed mean temperature gradient, the inertial clustering is very weak for solid particles with the diameter 10 microns and Reynolds numbers Re =250. Our theoretical predictions are in a good agreement with the obtained experimental results.Comment: 16 pages, 4 figures, REVTEX4, revised versio

Genetics of anophthalmia and microphthalmia. Part 1, Non-syndromic anophthalmia/microphthalmia

Eye formation is the result of coordinated induction and differentiation processes during embryogenesis. Disruption of any one of these events has the potential to cause ocular growth and structural defects, such as anophthalmia and microphthalmia (A/M). A/M can be isolated or occur with systemic anomalies, when they may form part of a recognizable syndrome. Their etiology includes genetic and environmental factors; several hundred genes involved in ocular development have been identified in humans or animal models. In humans, around 30 genes have been repeatedly implicated in A/M families, although many other genes have been described in single cases or families, and some genetic syndromes include eye anomalies occasionally as part of a wider phenotype. As a result of this broad genetic heterogeneity, with one or two notable exceptions, each gene explains only a small percentage of cases. Given the overlapping phenotypes, these genes can be most efficiently tested on panels or by whole exome/genome sequencing for the purposes of molecular diagnosis. However, despite whole exome/genome testing more than half of patients currently remain without a molecular diagnosis. The proportion of undiagnosed cases is even higher in those individuals with unilateral or milder phenotypes. Furthermore, even when a strong gene candidate is available for a patient, issues of incomplete penetrance and germinal mosaicism make diagnosis and genetic counselling challenging. In this review, we present the main genes implicated in nonsyndromic human A/M phenotypes and, for practical purposes, classify them according to the most frequent or predominant phenotype each is associated with. Our intention is that this will allow clinicians to rank and prioritize their molecular analyses and interpretations according to the phenotypes of their patients

USING VIRTUAL OR AUGMENTED REALITY for the TIME-BASED STUDY of COMPLEX UNDERWATER ARCHAEOLOGICAL EXCAVATIONS

International audienceCultural Heritage (CH) resources are partial, heterogeneous, discontinuous, and subject to ongoing updates and revisions. The use of semantic web technologies associated with 3D graphical tools is proposed to improve access, exploration, exploitation and enrichment of these CH data in a standardized and more structured form. This article presents the monitoring work developed for more than ten years on the excavation of the Xlendi site. Around an exceptional shipwreck, the oldest from the Archaic period in the Western Mediterranean, we have set up a unique excavation at a depth of 110m assisted by a rigorous and continuous photogrammetry campaign. All the collected results are modelled by an ontology and visualized with virtual and augmented reality tools that allow a bidirectional link between the proposed graphical representations and the non-graphical archaeological data. It is also important to highlight the development of an innovative 3D mobile app that lets users study and understand the site as well as experience sensations close to those of a diver visiting the site

Random Operator Approach for Word Enumeration in Braid Groups

We investigate analytically the problem of enumeration of nonequivalent primitive words in the braid group B_n for n >> 1 by analysing the random word statistics and the target space on the basis of the locally free group approximation. We develop a "symbolic dynamics" method for exact word enumeration in locally free groups and bring arguments in support of the conjecture that the number of very long primitive words in the braid group is not sensitive to the precise local commutation relations. We consider the connection of these problems with the conventional random operator theory, localization phenomena and statistics of systems with quenched disorder. Also we discuss the relation of the particular problems of random operator theory to the theory of modular functionsComment: 36 pages, LaTeX, 4 separated Postscript figures, submitted to Nucl. Phys. B [PM

Orientações para a avaliação das intervenções visando a prevenção dos Problemas Músculo-Esqueléticos ligados ao trabalho

Mejorar las prácticas de intervención constituye hoy en día un desafío en el campo de la prevención de lesiones músculo esqueléticas (LMS) relacionadas con el trabajo. El desarrollo de conocimientos sobre la intervención en las empresas es un desafío para la intervención dirigida a su evaluación. La investigación internacional en el campo de las LMS concentra sus trabajo y recomendaciones sobre la evaluación de los efectos de las intervenciones mediante la evaluación de los síntomas de salud o de las exposiciones. En este texto mostramos en primer lugar, que esta orientación supone que se reúnan un cierto número de condiciones importantes, generalmente subestimadas y a menudo difíciles de reunir. Proponemos que se tomen en cuenta, en tanto criterios complementarios de la evaluación, los indicadores relacionados a la actividad de trabajo y a los márgenes de maniobra, aunque señalamos que estos indicadores necesitan ser trabajados para volverlos operacionales. En segundo lugar, sostenemos que para desarrollar conocimientos sobre la intervención se necesita describir precisamente el proceso de intervención y tomar en cuenta el contexto en el que se desarrolla, por ello, la evaluación de sus efectos es insuficiente para desarrollar conocimientos sobre la intervención. Por último, la discusión señala que, desde nuestra perspectiva, la evaluación de las intervenciones constituye un proyecto en sí y que este contribuye directamente a la transformación del trabajo

The effect of cigarette smoke exposure on the development of inflammation in lungs, gut and joints of TNFΔARE mice

The inflammatory cytokine TNF-alpha is a central mediator in many immune-mediated diseases, such as Crohn's disease (CD), spondyloarthritis (SpA) and chronic obstructive pulmonary disease (COPD). Epidemiologic studies have shown that cigarette smoking (CS) is a prominent common risk factor in these TNF-dependent diseases. We exposed TNF Delta ARE mice; in which a systemic TNF-alpha overexpression leads to the development of inflammation; to 2 or 4 weeks of air or CS. We investigated the effect of deregulated TNF expression on CS-induced pulmonary inflammation and the effect of CS exposure on the initiation and progression of gut and joint inflammation. Upon 2 weeks of CS exposure, inflammation in lungs of TNF Delta ARE mice was significantly aggravated. However, upon 4 weeks of CS-exposure, this aggravation was no longer observed. TNF Delta ARE mice have no increases in CD4+ and CD8+ T cells and a diminished neutrophil response in the lungs after 4 weeks of CS exposure. In the gut and joints of TNF Delta ARE mice, 2 or 4 weeks of CS exposure did not modulate the development of inflammation. In conclusion, CS exposure does not modulate gut and joint inflammation in TNF Delta ARE mice. The lung responses towards CS in TNF Delta ARE mice however depend on the duration of CS exposure