417 research outputs found
Feeding of plankton in turbulent oceans and lakes
Analytical models for the statistical distribution of the gut content of fish larvae in a turbulent ocean environment are compared to data obtained in a field experiment. The proposed model allows the nutrition state and thereby the survival probability of plankton populations to be estimated for given conditions and parameters characterizing their environment, i.e., prey concentrations and turbulence levels. These parameters are all available in the field data. Other parameters such as the capture range and fields of view together with a characteristic time for digesting prey are assumed to be known. The analysis allows an estimate for the probability density of the gut content of plankton in terms of the number of nauplii in the gut. In particular, the analytical results give a basis for evaluating the average gut content of a given plankton population on the basis of basic information concerning the prey concentration and the turbulence intensity. Also analytical models for the prey capture rates are compared with results based on the field data. The analysis emphasizes the effects of turbulence.publishedVersio
Two-Dimensional Helioseismic Power, Phase, and Coherence Spectra of {\it Solar Dynamics Observatory} Photospheric and Chromospheric Observables
While the {\it Helioseismic and Magnetic Imager} (HMI) onboard the {\it Solar
Dynamics Observatory} (SDO) provides Doppler velocity [], continuum
intensity [], and line-depth [] observations, each of which is
sensitive to the five-minute acoustic spectrum, the {\it Atmospheric Imaging
Array} (AIA) also observes at wavelengths -- specifically the 1600 and 1700
Angstrom bands -- that are partly formed in the upper photosphere and have good
sensitivity to acoustic modes. In this article we consider the characteristics
of the spatio--temporal Fourier spectra in AIA and HMI observables for a
15-degree region around NOAA Active Region 11072. We map the
spatio--temporal-power distribution for the different observables and the HMI
Line Core [], or Continuum minus Line Depth, and the phase and coherence
functions for selected observable pairs, as a function of position and
frequency. Five-minute oscillation power in all observables is suppressed in
the sunspot and also in plage areas. Above the acoustic cut-off frequency, the
behaviour is more complicated: power in HMI is still suppressed in the
presence of surface magnetic fields, while power in HMI and the AIA bands
is suppressed in areas of surface field but enhanced in an extended area around
the active region, and power in HMI is enhanced in a narrow zone around
strong-field concentrations and suppressed in a wider surrounding area. The
relative phase of the observables, and their cross-coherence functions, are
also altered around the active region. These effects may help us to understand
the interaction of waves and magnetic fields in the different layers of the
photosphere, and will need to be taken into account in multi-wavelength local
helioseismic analysis of active regions.Comment: 18 pages, 15 figures, to be published in Solar Physic
The impact of COVID-19 on research
This article is made available for unrestricted research re-use and secondary analysis in any form or be any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.Coronavirus disease 2019 (COVID-19) has swept across the globe causing hundreds of thousands of deaths, shutting down economies, closing borders and wreaking havoc on an unprecedented scale. It has strained healthcare services and personnel to the brink in many regions and will certainly deeply mark medical research both in the short and long-term
An integrated space physics instrument (ISPI) for Solar Probe
Instruments for the Solar Probe mission must be designed not only to address the unique scientific measurement requirements, but must be compatible with the modest resource dollars as well as tight constraints on mass and power. Another unique aspect of the Solar Probe mission is its constraint on telemetry and the fact that the prime science is conducted in a single flyby. The instrument system must be optimized to take advantage of the telemetry and observing time available. JPL, together with industry and university partners, is designing an Integrated Space Physics Instrument (ISPI) which will measure magnetic fields, plasma waves, thermal plasma, energetic particles, dust, and perform EUV/visible and coronal imaging for the Solar Probe mission. ISPI uses a new architecture and incorporates technology which not only eliminates unnecessary duplication of function, but allows sensors to share data and optimize science. The current ISPI design goal (for a flight package) is a 5 kilogram/10 watt payload. © 1997 American Institute of Physics.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87393/2/131_1.pd
The battle between fake news and science
Fake news is fabricated information that mimics news media content yet lacks the editorial norms and processes that ensure accuracy and credibility [ [1] ]. This includes misinformation (misleading information) and disinformation (false information purposely spread to deceive people)
Properties of high-frequency wave power halos around active regions: an analysis of multi-height data from HMI and AIA onboard SDO
We study properties of waves of frequencies above the photospheric acoustic
cut-off of 5.3 mHz, around four active regions, through spatial maps
of their power estimated using data from Helioseismic and Magnetic Imager (HMI)
and Atmospheric Imaging Assembly (AIA) onboard Solar Dynamics Observatory
(SDO). The wavelength channels 1600 {\AA} and 1700 {\AA} from AIA are now known
to capture clear oscillation signals due to helioseismic p modes as well as
waves propagating up through to the chromosphere. Here we study in detail, in
comparison with HMI Doppler data, properties of the power maps, especially the
so called 'acoustic halos' seen around active regions, as a function of wave
frequencies, inclination and strength of magnetic field (derived from the
vector field observations by HMI) and observation height. We infer possible
signatures of (magneto-)acoustic wave refraction from the observation height
dependent changes, and hence due to changing magnetic strength and geometry, in
the dependences of power maps on the photospheric magnetic quantities. We
discuss the implications for theories of p mode absorption and mode conversions
by the magnetic field.Comment: 22 pages, 12 figures, Accepted by journal Solar Physic
Ets homologous factor regulates pathways controlling response to injury in airway epithelial cells
Ets homologous factor (EHF) is an Ets family transcription factor expressed in many epithelial cell types including those lining the respiratory system. Disruption of the airway epithelium is central to many lung diseases, and a network of transcription factors coordinates its normal function. EHF can act as a transcriptional activator or a repressor, though its targets in lung epithelial cells are largely uncharacterized. Chromatin immunoprecipitation followed by deep sequencing (ChIP-seq), showed that the majority of EHF binding sites in lung epithelial cells are intergenic or intronic and coincide with putative enhancers, marked by specific histone modifications. EHF occupies many genomic sites that are close to genes involved in intercellular and cellâmatrix adhesion. RNA-seq after EHF depletion or overexpression showed significant alterations in the expression of genes involved in response to wounding. EHF knockdown also targeted genes in pathways of epithelial development and differentiation and locomotory behavior. These changes in gene expression coincided with alterations in cellular phenotype including slowed wound closure and increased transepithelial resistance. Our data suggest that EHF regulates gene pathways critical for epithelial response to injury, including those involved in maintenance of barrier function, inflammation and efficient wound repair
A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication
Herpes simplex virus type 1 (HSV-1) is a neurotropic virus causing vesicular oral or genital skin lesions, meningitis and other diseases particularly harmful in immunocompromised individuals. To comprehensively investigate the complex interaction between HSV-1 and its host we combined two genome-scale screens for host factors (HFs) involved in virus replication. A yeast two-hybrid screen for protein interactions and a RNA interference (RNAi) screen with a druggable genome small interfering RNA (siRNA) library confirmed existing and identified novel HFs which functionally influence HSV-1 infection. Bioinformatic analyses found the 358 HFs were enriched for several pathways and multi-protein complexes. Of particular interest was the identification of Med23 as a strongly anti-viral component of the largely pro-viral Mediator complex, which links specific transcription factors to RNA polymerase II. The anti-viral effect of Med23 on HSV-1 replication was confirmed in gain-of-function gene overexpression experiments, and this inhibitory effect was specific to HSV-1, as a range of other viruses including Vaccinia virus and Semliki Forest virus were unaffected by Med23 depletion. We found Med23 significantly upregulated expression of the type III interferon family (IFN-λ) at the mRNA and protein level by directly interacting with the transcription factor IRF7. The synergistic effect of Med23 and IRF7 on IFN-λ induction suggests this is the major transcription factor for IFN-λ expression. Genotypic analysis of patients suffering recurrent orofacial HSV-1 outbreaks, previously shown to be deficient in IFN-λ secretion, found a significant correlation with a single nucleotide polymorphism in the IFN-λ3 (IL28b) promoter strongly linked to Hepatitis C disease and treatment outcome. This paper describes a link between Med23 and IFN-λ, provides evidence for the crucial role of IFN-λ in HSV-1 immune control, and highlights the power of integrative genome-scale approaches to identify HFs critical for disease progression and outcome
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