Cycling injuries and alcohol

Background: Most of the cycling accidents that occur in Finland do not end up in the official traffic accident statistics. Thus, there is minimal information on these accidents and their consequences, particularly in cases in which alcohol was involved. The focus of the present study is on cycling accidents and injuries involving alcohol in particular. Methods: Data on patients visiting the emergency department at North Kymi Hospital because of a cycling accident was prospectively collected for two years, from June 1, 2004 to May 31, 2006. Blood alcohol concentration (BAC) was measured on admission with a breath analyser. The severity of the cycling injuries was classified according to the Abbreviated Injury Scale (AIS). Results: A total of 217 cycling accidents occurred. One third of the injured cyclists were involved with alcohol at the time of visiting the hospital. Of these, 85% were males. A blood alcohol concentration of Conclusions: Cyclists involved with alcohol were, in most cases, heavily intoxicated and were not wearing a bicycle helmet. Head injuries were more common among these cyclists than among sober cyclists. As cycling continues to increase, it is important to monitor cycling accidents, improve the accident statistics and heighten awareness of the risks of head injuries when cycling under the influence of alcohol. (c) 2018 Elsevier Ltd. All rights reserved.Peer reviewe

Measurement and modeling of ablation of the bottom of supraglacial lakes in western Greenland

We report measurements of ablation rates of the bottom of two supraglacial lakes and of temperatures at different depths collected during the summers of 2010 and 2011 in west Greenland. To our knowledge, this is the first time that such data sets are reported and discussed in the literature. The measured ablation rates at the bottom of the two lakes are of the order of ∼6 cm/day, versus a rate of ∼2.5–3 cm/day in the case of bare ice of surrounding areas. Though our measurements suggest the presence of a vertical temperature gradient, it is not possible to draw final conclusions as the measured gradient is smaller than the accuracy of our temperature sensors. In-situ measurements are compared with the results of a thermodynamic model forced with the outputs of a regional climate model. In general, the model is able to satisfactorily reproduce the measured quantities with RMSE of the order of 3–4 cm for the ablation and ∼1.5°C in the case of water temperature. Our results confirm that the ablation at the bottom of supraglacial lakes plays an important role on the overall lake volume with the ablation in the case of ice covered by a lake being 110–135% of that over bare ice at nearby locations. Beside ice sheet hydrological implications, melting at the bottom of a supraglacial lake might affect estimates of lake volume from spaceborne visible and near-infrared measurements

Time--delay autosynchronization of the spatio-temporal dynamics in resonant tunneling diodes

The double barrier resonant tunneling diode exhibits complex spatio-temporal patterns including low-dimensional chaos when operated in an active external circuit. We demonstrate how autosynchronization by time--delayed feedback control can be used to select and stabilize specific current density patterns in a noninvasive way. We compare the efficiency of different control schemes involving feedback in either local spatial or global degrees of freedom. The numerically obtained Floquet exponents are explained by analytical results from linear stability analysis.Comment: 10 pages, 16 figure

Programm

Dieser Band dokumentiert die Reden, welche am 7. Juli 2006 in Hamburg anlässlich der feierlichen Eröffnung des Carl Friedrich von Weizsäcker-Zentrum für Naturwissenschaft und Friedensforschung, gehalten wurden. Als Hauptredner waren Alyson J. K. Bailes, die Leiterin des Stockholmer Friedensforschungsinstitutes (SIPRI), Staatsminister a.D., Prof. Egon Bahr, ehemaliger Leiter des Hamburger Friedensforschungsinstituts (IFSH), Prof. Ernst Ulrich von Weizsäcker, ein Sohn des Namensgebers des ZNF, und Prof. Wolfgang Panofsky aus Stanford, USA geladen. Mit der Gründung des Zentrums an der Universität Hamburg, dessen Leitung Prof. Dr. Martin Kalinowski obliegt, hat die naturwissenschaftliche Friedensforschung eine bundesweit einmalige institutionelle Verankerung erhalten. Zusammen mit dem Institut für Friedensforschung und Sicherheitspolitik (IFSH) in Hamburg entsteht ein inter- und multidisziplinär ausgerichteter Forschungsverbund, durch den neue Möglichkeiten eröffnet werden, die Wechselwirkung von Naturwissenschaften, Konflikten und internationaler Sicherheit vor dem Hintergrund der Leitbilder Frieden und Nachhaltigkeit zu erforschen und diese auch in die Ausbildung von Naturwissenschaftlern zu integrieren.This volume documents the speeches given on July 7, 2006 in Hamburg on the occasion of the ceremonial opening of the Carl Friedrich von Weizsäcker Center for Science and Peace Research (Zentrum für Naturwissenschaft und Friedensforschung, ZNF). The keynote speakers were Alyson J. K. Bailes, Head of the Stockholm Peace Research Institute (SIPRI), former Minister of State, Prof. Egon Bahr, former Head of the Hamburg Peace Research Institute (scientific peace research has gained a unique institutional foothold in Germany. Together with the Institut für Friedensforschung und Sicherheitpolitik, IFSH), Prof. Ernst Ulrich von Weizsäcker, a son of the namesake of the ZNF, and Prof. Wolfgang Panofsky from Stanford, USA. With the founding of the Centre at the University of Hamburg, headed by Prof. Dr. Martin Kalinowski, scientific peace research has gained a unique institutional foothold in Germany. Together with the IFSH in Hamburg an inter- and multidisciplinary research network is being established which will open up new opportunities to explore the interaction of natural sciences, conflicts and international security against the background of the guiding principles of peace and sustainability and to integrate them into the training of natural scientists

An Evaluation Model For Web-based 3D Mass Customization Toolkit Design

The development of geometric modelling technologies and web technologies provides the ability to present a virtual 3D product in a mass customization (MC) toolkit. Compared with 2D graphic toolkits, 3D toolkit design requires better consideration of individual customer needs, consumer and toolkit interaction, and also a means of integrating with the underlying technical infrastructure. However, there is currently no widely accepted model or criteria to regulate and evaluate 3D MC toolkit design. Given these considerations, in this paper we provide an evaluation model for web-based 3D toolkits and a heuristic evaluation of two representative commercial web-based 3D toolkits. The evaluation results indicate the usefulness and effectiveness of the model as a scale for evaluating 3D toolkits. It also reveals that despite a fair amount of effort that has been devoted to theoretical research, current 3D toolkits are still at an early development stage. We therefore conclude this paper by identifying and encouraging further topics and questions as directions for future research

Survival in amoeba: a major selection pressure on the presence of bacterial copper and zinc resistance determinants?: identification of a "copper pathogenicity island"

The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance genes in bacteria. In this review, we outline evidence supporting this hypothesis, as well as highlight the correlation between metal resistance and pathogenicity in bacteria. In addition, we introduce and characterize the "copper pathogenicity island" identified in Escherichia coli and Salmonella strains isolated from copper- and zinc-fed Danish pigs

From Producer Innovation to User and Open Collaborative Innovation

In this paper we assess the economic viability of innovation by producers relative to two increasingly important alternative models: innovations by single user individuals or firms, and open collaborative innovation. We analyze the design costs and architectures and communication costs associated with each model. We conclude that both innovation by individual users and open collaborative innovation increasingly compete with and may displace producer innovation in many parts of the economy. We explain why this represents a paradigm shift with respect to innovation research, policymaking, and practice. We discuss important implications and offer suggestions for further research

Working people with type 1 diabetes in the Finnish population

Peer reviewe

Vitamin D Induction of the Human Antimicrobial Peptide Cathelicidin in the Urinary Bladder

The urinary tract is frequently being exposed to potential pathogens and rapid defence mechanisms are therefore needed. Cathelicidin, a human antimicrobial peptide is expressed and secreted by bladder epithelial cells and protects the urinary tract from infection. Here we show that vitamin D can induce cathelicidin in the urinary bladder. We analyzed bladder tissue from postmenopausal women for expression of cathelicidin, before and after a three-month period of supplementation with 25-hydroxyvitamin D3 (25D3). Cell culture experiments were performed to elucidate the mechanisms for cathelicidin induction. We observed that, vitamin D per se did not up-regulate cathelicidin in serum or in bladder tissue of the women in this study. However, when the bladder biopsies were infected with uropathogenic E. coli (UPEC), a significant increase in cathelicidin expression was observed after 25D3 supplementation. This observation was confirmed in human bladder cell lines, even though here, cathelicidin induction occurred irrespectively of infection. Vitamin D treated bladder cells exerted an increased antibacterial effect against UPEC and colocalization to cathelicidin indicated the relevance of this peptide. In the light of the rapidly growing problem of resistance to common urinary tract antibiotics, we suggest that vitamin D may be a potential complement in the prevention of UTI