2,967 research outputs found
2D vs. 3D pain visualization: User preferences in a spinal cord injury cohort
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2011 Springer VerlagResearch on pain experienced after Spinal Cord Injury (SCI) has revealed that not only are there several types of pain present in the same individual with this kind of trauma, but also that people who suffer such an injury can describe the characteristics of the same type of pain in different ways. Making it possible, therefore, to more precisely describe pain experience could prove to be vital for an increased quality of life. Accordingly, fifteen individuals with pain after SCI were asked to describe their pain experience using a 3 Dimensional (3D) model of the human body that could be used as an aid in communicating their pain. The results of this study suggest that the consensus of the participants approved the ability of the 3D model to more accurately describe their pain, an encouraging outcome towards the use of 3D technology in support of post SCI pain rehabilitation
Age-dependent differences in demographics, risk factors, co-morbidity, etiology, management, and clinical outcome of acute ischemic stroke
Background : Comparisons between younger and older stroke patients including comorbidities are limited. Methods : Prospective data of consecutive patients with first ever acute ischemic stroke were compared between younger (†45 years) and older patients (> 45 years). Results : Among 1004 patients, 137 (14 %) were †45 years. Younger patients were more commonly female (57 % versus 34 %; p < 0.0001), had a lower frequency of diabetes (1 % versus 15 %; p < 0.0001), hypercholesterolemia (26 % versus 56 %; p < 0.0001), hypertension (19 % versus 65 %; p < 0.0001), coronary heart disease (14 % versus 40 %; p < 0.0001), and a lower mean Charlson co-morbidity index (CCI), (0.18 versus 0.84; p < 0.0001). Tobacco use was more prevalent in the young (39 % versus 26 %; P < 0.0001). Large artery disease (2 % versus 21 %; p < 0.0001), small artery disease (3 % versus 12 %; p = 0.0019) and atrial fibrillation (1 % versus 17 %; p = 0.001) were less common in young patients, while other etiologies (31 % versus 9 %; p < 0.0001), patent foramen ovale or atrial septal defect (44 % versus 26 %; p < 0.0001), and cervical artery dissection (26 % versus 7 %; p < 0.0001) were more frequent. A favorable outcome (mRS 0 or 1) was more common (57.4 % versus 46.9 %; p = 0.023), and mortality (5.1 % versus 12 %; p = 0.009) was lower in the young. After regression analysis, there was no independent association between age and outcome (p = 0.206) or mortality (p = 0.073). Baseline NIHSS score (p < 0.0001), diabetes (p = 0.041), and CCI (p = 0.002) independently predicted an unfavorable outcome. Conclusions : Younger patients were more likely to be female, had different risk factors and etiologies and fewer co-morbidities. There was no independent association between age and clinical outcome or mortalit
Performance of the LHCb Vertex Detector Alignment Algorithm determined with Beam Test Data
LHCb is the dedicated heavy flavour experiment at the Large Hadron Collider
at CERN. The partially assembled silicon vertex locator (VELO) of the LHCb
experiment has been tested in a beam test. The data from this beam test have
been used to determine the performance of the VELO alignment algorithm. The
relative alignment of the two silicon sensors in a module and the relative
alignment of the modules has been extracted. This alignment is shown to be
accurate at a level of approximately 2 micron and 0.1 mrad for translations and
rotations, respectively in the plane of the sensors. A single hit precision at
normal track incidence of about 10 micron is obtained for the sensors. The
alignment of the system is shown to be stable at better than the 10 micron
level under air to vacuum pressure changes and mechanical movements of the
assembled system.Comment: accepted for publication in NIM
Assessing the perspective of well-being of older patients with multiple morbidities by using the LAVA tool-a person-centered approach
BACKGROUND: Older patients with multiple morbidities are a particularly vulnerable population that is likely to face complex medical decisions at some time in their lives. A patient-centered medical care fosters the inclusion of the patientsâ perspectives, priorities, and complaints into clinical decision making. METHODS: This article presents a short and non-normative assessment tool to capture the priorities and problems of older patients. The so-called LAVA (âLife and Vitality Assessmentâ) tool was developed for practical use in seniors in the general population and for residents in nursing homes in order to gain more knowledge about the patients themselves as well as to facilitate access to the patients. The LAVA tool conceptualizes well-being from the perspectives of older individuals themselves rather than from the perspectives of outside individuals. RESULTS: The LAVA tool is graphically presented and the assessment is explained in detail. Exemplarily, the outcomes of the assessments with the LAVA of three multimorbid older patients are presented and discussed. In each case, the assessment pointed out resources as well as at least one problem area, rated as very important by the patients themselves. CONCLUSIONS: The LAVA tool is a short, non-normative, and useful approach that encapsulates the perspectives of well-being of multimorbid patients and gives insights into their resources and problem areas. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-021-02342-3
PainDroid: An android-based virtual reality application for pain assessment
Earlier studies in the field of pain research suggest that little efficient intervention currently exists in response to the exponential increase in the prevalence of pain. In this paper, we present an Android application (PainDroid) with multimodal functionality that could be enhanced with Virtual Reality (VR) technology, which has been designed for the purpose of improving the assessment of this notoriously difficult medical concern. Pain- Droid has been evaluated for its usability and acceptability with a pilot group of potential users and clinicians, with initial results suggesting that it can be an effective and usable tool for improving the assessment of pain. Participant experiences indicated that the application was easy to use and the potential of the application was similarly appreciated by the clinicians involved in the evaluation. Our findings may be of considerable interest to healthcare providers, policy makers, and other parties that might be actively involved in the area of pain and VR research
Two-loop representations of low-energy pion form factors and pi-pi scattering phases in the presence of isospin breaking
Dispersive representations of the pi-pi scattering amplitudes and pion form
factors, valid at two-loop accuracy in the low-energy expansion, are
constructed in the presence of isospin-breaking effects induced by the
difference between the charged and neutral pion masses. Analytical expressions
for the corresponding phases of the scalar and vector pion form factors are
computed. It is shown that each of these phases consists of the sum of a
"universal" part and a form-factor dependent contribution. The first one is
entirely determined in terms of the pi-pi scattering amplitudes alone, and
reduces to the phase satisfying Watson's theorem in the isospin limit. The
second one can be sizeable, although it vanishes in the same limit. The
dependence of these isospin corrections with respect to the parameters of the
subthreshold expansion of the pi-pi amplitude is studied, and an equivalent
representation in terms of the S-wave scattering lengths is also briefly
presented and discussed. In addition, partially analytical expressions for the
two-loop form factors and pi-pi scattering amplitudes in the presence of
isospin breaking are provided.Comment: 57 pages, 12 figure
Willingness to pay for municipality hospital services in rural Japan: a contingent valuation study
<p>Abstract</p> <p>Background</p> <p>The Japanese healthcare system has undergone reforms to address the struggles that municipality hospitals face. Reform guidelines clearly define criteria for administrative improvement. However, criteria to evaluate the demand for healthcare provisions in rural Japan, including the needs of rural residents for municipality hospitals in particular have not been specified. The purpose of this paper is to measure residents' willingness to pay (WTP) for municipality hospital services using the contingent valuation method, and to evaluate municipality hospital valuation on the basis of WTP. K town, located in the Hokkaido prefecture of Japan, was selected as the location for this study. Participants were recruited by a town hall healthcare administrator, hospital and clinic staff, and a local dentist. Participants were asked what amount they would be willing to pay as taxes to continue accessing the services of the municipality hospital for one year by using open-ended questions in face-to-face interviews.</p> <p>Findings</p> <p>Forty-eight residents were initially recruited, and 40 participants were selected for the study (response rate 83%). As compared to K town's population, this data slanted toward the elderly, although there was no significant difference in frequency among the characteristics. The median WTP was estimated at 39,484 yen (308.95-615.96). Logistic regression revealed no significant factors affecting WTP.</p> <p>Conclusions</p> <p>If the total amount of residents' WTP for the municipality hospital were to be estimated by this result, it would calculate with 129,586,000 yen ($1,439,844). This is approximately equal to the amount of money to be transferred from the general account of the government of K town, more than one-half of the town tax of K town, and about two-fold in comparison to Japan as a whole. This showed that K town's residents placed a high valuation on the municipality hospital, which nearly equalled the amount that the K town government provided to the municipality hospital to cover its annual deficit. K town residents had come to expect not only general clinical practice, but also emergency medical services and night practice provided by their own town's municipality hospital. WTP can be used as a measure of hospital evaluation because it reflects the importance of the hospital to the residents in its region.</p
Performance of the LHCb vertex locator
The Vertex Locator (VELO) is a silicon microstrip detector that surrounds the proton-proton interaction region in the LHCb experiment. The performance of the detector during the first years of its physics operation is reviewed. The system is operated in vacuum, uses a bi-phase CO2 cooling system, and the sensors are moved to 7 mm from the LHC beam for physics data taking. The performance and stability of these characteristic features of the detector are described, and details of the material budget are given. The calibration of the timing and the data processing algorithms that are implemented in FPGAs are described. The system performance is fully characterised. The sensors have a signal to noise ratio of approximately 20 and a best hit resolution of 4 ÎŒm is achieved at the optimal track angle. The typical detector occupancy for minimum bias events in standard operating conditions in 2011 is around 0.5%, and the detector has less than 1% of faulty strips. The proximity of the detector to the beam means that the inner regions of the n+-on-n sensors have undergone space-charge sign inversion due to radiation damage. The VELO performance parameters that drive the experiment's physics sensitivity are also given. The track finding efficiency of the VELO is typically above 98% and the modules have been aligned to a precision of 1 ÎŒm for translations in the plane transverse to the beam. A primary vertex resolution of 13 ÎŒm in the transverse plane and 71 ÎŒm along the beam axis is achieved for vertices with 25 tracks. An impact parameter resolution of less than 35 ÎŒm is achieved for particles with transverse momentum greater than 1 GeV/c
Precision luminosity measurements at LHCb
Measuring cross-sections at the LHC requires the luminosity to be determined accurately at each centre-of-mass energy âs. In this paper results are reported from the luminosity calibrations carried out at the LHC interaction point 8 with the LHCb detector for âs = 2.76, 7 and 8 TeV (proton-proton collisions) and for âsNN = 5 TeV (proton-lead collisions). Both the "van der Meer scan" and "beam-gas imaging" luminosity calibration methods were employed. It is observed that the beam density profile cannot always be described by a function that is factorizable in the two transverse coordinates. The introduction of a two-dimensional description of the beams improves significantly the consistency of the results. For proton-proton interactions at âs = 8 TeV a relative precision of the luminosity calibration of 1.47% is obtained using van der Meer scans and 1.43% using beam-gas imaging, resulting in a combined precision of 1.12%. Applying the calibration to the full data set determines the luminosity with a precision of 1.16%. This represents the most precise luminosity measurement achieved so far at a bunched-beam hadron collider
Performance of the LHCb muon system
The performance of the LHCb Muon system and its stability across the full
2010 data taking with LHC running at ps = 7 TeV energy is studied. The
optimization of the detector setting and the time calibration performed with
the first collisions delivered by LHC is described. Particle rates, measured
for the wide range of luminosities and beam operation conditions experienced
during the run, are compared with the values expected from simulation. The
space and time alignment of the detectors, chamber efficiency, time resolution
and cluster size are evaluated. The detector performance is found to be as
expected from specifications or better. Notably the overall efficiency is well
above the design requirementsComment: JINST_015P_1112 201
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