Пожарная и промышленная безопасность на предприятиях нефтегазодобывающей отрасли

Работа посвящена анализу теоретических основ обеспечения пожарной безопасности, улучшению практических приемов и методах противопожарной защиты, при повседневной эксплуатации установки подготовки нефти на опасном производственном объекте в области пожарной безопасности. В результате исследования изучены методы эксплуатации установки подготовки нефти на опасном производственном объекте, позволяющие не только предотвратить возникновение аварии или пожара, но и быстро ликвидировать последствия. Противопожарные мероприятия существенно повышают уровень пожарной безопасности своих объектов и снижают потери от пожаров.The work is devoted to the analysis of the theoretical foundations of fire safety, improvement of practical techniques and methods of fire protection, in the daily operation of the oil treatment plant at a hazardous production facility in the field of fire safety. As a result of the study, the methods of operation of an oil treatment plant at a dangerous production facility were studied, allowing not only to prevent an accident or fire, but also to quickly eliminate the consequences. Fire-fighting measures significantly increase the level of fire safety of their facilities and reduce losses from fires

Access and allocation in earth system governance: Water and climate change compared

A significant percentage of the global population does not yet have access to safe drinking water, sufficient food or energy to live in dignity. There is a continuous struggle to allocate the earth's resources among users and uses. This article argues that distributional problems have two faces: access to basic resources or ecospace; and, the allocation of environmental resources, risks, burdens, and responsibilities for causing problems. Furthermore, addressing problems of access and allocation often requires access to social processes (science, movements and law). Analysts, however, have tended to take a narrow, disciplinary approach although an integrated conceptual approach may yield better answers. This article proposes a multi-disciplinary perspective to the problem of access and allocation and illustrates its application to water management and climate change. © The Author(s) 2010

Profit enhancing competitive pressure in vertically related industries

Coevolution of viruses and their hosts represents a dynamic molecular battle between the immune system and viral factors that mediate immune evasion. After the abandonment of smallpox vaccination, cowpox virus infections are an emerging zoonotic health threat, especially for immunocompromised patients. Here we delineate the mechanistic basis of how cowpox viral CPXV012 interferes with MHC class I antigen processing. This type II membrane protein inhibits the coreTAP complex at the step after peptide binding and peptide-induced conformational change, in blocking ATP binding and hydrolysis. Distinct from other immune evasion mechanisms, TAP inhibition is mediated by a short ER-lumenal fragment of CPXV012, which results from a frameshift in the cowpox virus genome. Tethered to the ER membrane, this fragment mimics a high ER-lumenal peptide concentration, thus provoking a trans-inhibition of antigen translocation as supply for MHC I loading. These findings illuminate the evolution of viral immune modulators and the basis of a fine-balanced regulation of antigen processing