40 research outputs found

    ÜBER DIOXIMINKOMPLEXE DER ÜBERGANGSMETALLE. LXXX. KATALYTISCHE POLAROGRAPHISCHE REDUKTION VON HYDROXYLAMIN IN ANWESENHEIT VON EISEN(II)-DIOXIMINKOMPLEXEN

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    The stability constants of the iron(II)-nyoximine chelates: Fe(Nyox. H)* and Fe(Nyox. H)2 in aqueous NaClO4 -Britton-Robinson buffer solutions have been determined polarographi- cally. In the Fe(II)-nyoxime system appears a catalytic wave in the presence of hydroxylamine, with a half wave potential of -0.90 V (vs. SCE), suitable for the quantitative polarographic determination of hydroxylamine, also in the presence of hydrazine

    Effects of serelaxin in patients with acute heart failure

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    Background: Serelaxin is a recombinant form of human relaxin-2, a vasodilator hormone that contributes to cardiovascular and renal adaptations during pregnancy. Previous studies have suggested that treatment with serelaxin may result in relief of symptoms and in better outcomes in patients with acute heart failure. Methods: In this multicenter, double-blind, placebo-controlled, event-driven trial, we enrolled patients who were hospitalized for acute heart failure and had dyspnea, vascular congestion on chest radiography, increased plasma concentrations of natriuretic peptides, mild-to-moderate renal insufficiency, and a systolic blood pressure of at least 125 mm Hg, and we randomly assigned them within 16 hours after presentation to receive either a 48-hour intravenous infusion of serelaxin (30 μg per kilogram of body weight per day) or placebo, in addition to standard care. The two primary end points were death from cardiovascular causes at 180 days and worsening heart failure at 5 days. Results: A total of 6545 patients were included in the intention-to-treat analysis. At day 180, death from cardiovascular causes had occurred in 285 of the 3274 patients (8.7%) in the serelaxin group and in 290 of the 3271 patients (8.9%) in the placebo group (hazard ratio, 0.98; 95% confidence interval [CI], 0.83 to 1.15; P=0.77). At day 5, worsening heart failure had occurred in 227 patients (6.9%) in the serelaxin group and in 252 (7.7%) in the placebo group (hazard ratio, 0.89; 95% CI, 0.75 to 1.07; P=0.19). There were no significant differences between the groups in the incidence of death from any cause at 180 days, the incidence of death from cardiovascular causes or rehospitalization for heart failure or renal failure at 180 days, or the length of the index hospital stay. The incidence of adverse events was similar in the two groups. Conclusions: In this trial involving patients who were hospitalized for acute heart failure, an infusion of serelaxin did not result in a lower incidence of death from cardiovascular causes at 180 days or worsening heart failure at 5 days than placebo. (Funded by Novartis Pharma; RELAX-AHF-2 ClinicalTrials.gov number, NCT01870778. opens in new tab.

    Overconfidence in Labor Markets

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    This chapter reviews how worker overconfidence affects labor markets. Evidence from psychology and economics shows that in many situations, most people tend to overestimate their absolute skills, overplace themselves relative to others, and overestimate the precision of their knowledge. The chapter starts by reviewing evidence for overconfidence and for how overconfidence affects economic choices. Next, it reviews economic explanations for overconfidence. After that, it discusses research on the impact of worker overconfidence on labor markets where wages are determined by bargaining between workers and firms. Here, three key questions are addressed. First, how does worker overconfidence affect effort provision for a fixed compensation scheme? Second, how should firms design compensation schemes when workers are overconfident? In particular, will a compensation scheme offered to an overconfident worker have higher-or lower-powered incentives than that offered to a worker with accurate self-perception? Third, can worker overconfidence lead to a Pareto improvement? The chapter continues by reviewing research on the impact of worker overconfidence on labor markets where workers can move between firms and where neither firms nor workers have discretion over wage setting. The chapter concludes with a summary of its main findings and a discussion of avenues for future research

    A Revealed Reference Point for Prospect Theory

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    Without an instrument to identify the reference point, prospect theory includes a degree of freedom that makes the model difficult to falsify. To address this issue, we propose a foundation for prospect theory that advances existing approaches with three innovations. First, the reference point is not known a priori; if preferences are reference-dependent, the reference point is revealed from behavior. Second, the key preference axiom is formulated as a consistency property for attitudes towards probabilities; it entails both a revealed preference test for reference-dependence and a tool suitable for empirical measurement. Third, minimal assumptions are imposed for outcomes, thereby extending the model to general settings. By incorporating these three features we deliver general foundations for prospect theory that show how reference points can be identified and how the model can be falsified

    Sacrifice for the Mandate of Heaven? Regression Discontinuity of Death Penalty Execution in Taiwan

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    © 2021 Western Social Science Association. The death penalty enjoys overwhelmingly cross-partisan support among Taiwanese citizens. Politicians, mass media actors, and anti-death-penalty activists all believe that death penalty executions boost the president’s approval. As a result, Taiwanese presidents are motivated to strategically execute prisoners, trying to improve their approval rate. To examine this myth, we exploit data from a nationally representative survey conducted in 2012; six inmates were unexpectedly executed during the survey period. This unique opportunity enables us to examine the causal relationship between implementing a welcoming policy and its effect on public opinion. Contrary to popular belief, however, the results of the regression discontinuity design indicate that death penalty executions in Taiwan did not boost the president’s approval rate at all. This non-finding holds after several robustness checks and difference-in-differences analyses. This result yields implications for the study of judicial politics and presidential approval
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