"Türk tiyatrosunu dünyaya tanıtan dergi":Kulis 50 yaşında

Taha Toros Arşivi, Dosya No: 205-Eski Tiyatro Dokümanlarıİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033

Isaura ve çevre yerleşimlerden demir çağı boyalı kapları

Çalışmanın konusunu, Isauria Bölgesi kentlerindeki yüzey araştırmalarında tespit edilen Demir Çağı boyalı çanak-çömlek parçaları oluşturmaktadır. Malzemeler, Isauria Bölgesi’nin önemli antik yerleşimleri Isaura başta olmak üzere Oduncu Kalesi, Cicek Höyük ve Çukurbağ Yel Değirmeni Kalesi buluntularıdır. Bu çalışmayla Isaura yerleşimi ve çevresi Demir Çağı kapları aracılığıyla söz konusu antik yerleşimler arasındaki ilişki anlaşılmaya çalışılmıştır. Değerlendirmeye aldığımız Isauria Bölgesi yerleşimleri kaplarında Alişar IV geleneği baskın olarak hissedilmektedir. Bazı kapların ise doğrudan Kilikia ithali olduğu görüşündeyiz. Bahsi geçen yerleşimlerde kazı çalışması olmadığı için kapların form ve bezemeleri, benzerleri ile karşılaştırılarak tarihlendirilmiştir.The subject of this study is the Iron Age painted ceramics that were found during the survey in the Isaura ancient city and its surroundings. The ceramic are the finds of the important ancient settlements of the Isauria Region, mainly Isaura, Oduncu Castle, Cicek Höyük and the Cukurbag Yel Değirmeni Castle. In this study, the relationship between the Isaura settlement and its surroundings was tried to be understood through Iron Age ceramics. Alişar IV tradition are felt predominantly in the ceramics of the Isauria Region settlements discussed in this study. Some ceramic are thought to be directly imported from Cilicia. Since there was no excavation works in these settlements, the forms and decorations of the ceramics were dated by comparing them with similar ones

Propionic acidemia: an extremely rare cause of hemophagocytic lymphohistiocytosis in an infant

Hemophagocytic lymphohystiocytosis (HLH) may be primary (inherited/familial) or secondary to infections, malignancies, and metabolic diseases. Cases including lysinuric protein intolerance, multiple sulfatase deficiency, galactosemia, Gaucher disease, Pearson syndrome, and galactosialidosis have previously been reported. It is unclear how the metabolites trigger HLH in metabolic diseases. A 2-month-old infant with lethargy, pallor, poor feeding, hepatosplenomegaly, fever and pancytopenia, was diagnosed with HLH and the HLH-2004 treatment protocol was initiated. Analysis for primary HLH gene mutations and metabolic screening tests were performed together; primary HLH gene mutations were negative, but hyperammonemia and elevated methyl citrate were detected. Propionic acidemia was diagnosed with tandem mass spectrometry in neonatal dried blood spot. We report this case of HLH secondary to propionic acidemia. Both metabolic disorder screening tests and gene mutation analysis may be performed simultaneously especially for early diagnosis in infants presenting with HLH

Flow cytometric analysis of platelet surface glycoproteins in the diagnosis of thirty-two Turkish patients with Glanzmann thrombasthenia: a multicenter experience

Background/aim: Glanzmann thrombasthenia (GT) is a rare autosomal recessively inherited bleeding disorder characterized by the quantitative (type 1 and type 2) or qualitative (type 3) deficiency in platelet membrane glycoprotein (GP) IIb/IIIa (CD41a/CD61) fibrinogen receptors. In type 1, 2, and 3, CD41a/CD61 expression is 5%, 5%-20% and above 20%, respectively. In this study, diagnosis of GT was confirmed and subgroups were identified in 32 Turkish patients by flow cytometry analysis. Materials and methods: CD41a/CD61 expression levels in platelet-rich plasma (PRP) obtained from peripheral venous EDTA blood samples were analyzed with a BD FACSCanto II flow cytometer (Becton Dickinson, Franklin Lakes, NJ, USA). GT subgroup analysis was performed by counting 50,000 events in the BD FACSDiva Software v6.1.3 program of the instrument. Results: In the present study, in blood samples of 32 patients from 23 families with GT and 22 healthy controls, co-expression levels of CD41a and CD61 in PRP was analyzed. 12 out of 23 families were consistent with type 1 GT (52.2%), 4 were consistent with type 2 GT (17.4%), and 7 were consistent with type 3 GT (30.4%). Conclusion: Especially due to consanguineous marriages, GT with various glycoprotein levels may be detected. As a result of the flow cytometry analysis of the present study with the highest GT patient population in Turkey, type 1 GT patients were the most common subgroup. In the determination of the GT subgroups; especially in the detection of type 3 GT, flow cytometry is the most sensitive glycoprotein analysis method. In addition to light transmission aggregometry, CD41a/CD61 study by flow cytometer confirms diagnosis when mutation analysis cannot be performed