150 research outputs found
Smittskydd vid veterinÀr fÀltverksamhet i hÀststall
Smittsamma sjukdomar orsakar lidande för drabbade individer och kan ge stora ekonomiska konsekvenser, dĂ€rför har ett aktivt smittskyddsarbete fördelar bĂ„de ur ett djurvĂ€lfĂ€rdsperspektiv och ur ett ekonomiskt perspektiv. Tre av de viktigaste endemiska hĂ€stsjukdomarna i Sverige Ă€r hĂ€stinfluensa, ekvint herpesvirus-1 och kvarka. Alla tre sjukdomarna ger symptom i övre luftvĂ€garna och ett smittsamt nosflöde. Sjukdomarna sprids direkt frĂ„n hĂ€st till hĂ€st och indirekt via kontaminering av omgivning och personer som hanterar sjuka hĂ€star. Ă
tgÀrder för att förhindra indirekt smittspridning verkar sÀllsynta i svenska hÀststall, endast ett fÄtal stall erbjuder besökare möjlighet att tvÀtta hÀnderna med varmt vatten och tvÄl.
HÀstar som flyttas mellan olika stall i samband med försÀljning, avel, trÀning och tÀvling Àr den största risken för att smittsamma sjukdomar ska spridas. MÀnniskor som rör sig mellan stall, till exempel veterinÀrer, Àr ocksÄ en riskfaktor men det finns ÄtgÀrder för smittskydd som minskar risken. KlÀdbyte mellan besök pÄ olika stall eller skyddsklÀder, skobad vid stallets entré eller lÄnestövlar Àr ÄtgÀrder som visat sig förebygga att ett stall blir infekterat. Vidare Àr handtvÀtt med varmt vatten och tvÄl effektivt för att avlÀgsna bÄde bakterier och virus frÄn hÀnder, vissa studier visar Àven att handdesinfektion fungerar lika bra och ibland bÀttre pÄ nÀmnda smittÀmnen.
MÄnga veterinÀrer uppger att de utför ett antal ÄtgÀrder av vikt för smittskyddet mellan besök pÄ olika gÄrdar. Det finns dock studier som visar att det Àr svÄrt att fÄ mÀnniskor att efterleva smittskyddsregler och att mÄnga mÀnniskor ocksÄ har en felaktig uppfattning om huruvida de har följt reglerna eller inte. Den psykosociala aspekten Àr en stor utmaning nÀr det kommer till smittskydd.
Hur stor roll veterinÀrens smittskydd och hygien har vid spridning av smittÀmnen kan diskuteras. MÄnga stall besöks av flertalet privatpersoner varje dag och stallets egna smittskyddsÄtgÀrder Àr mest troligt av större betydelse Àn den enskilda veterinÀrens. HÀstÀgare verkar dock ha stort förtroende för sin veterinÀr nÀr det gÀller smittskyddsÄtgÀrder och veterinÀren kan minska risken för smittspridning inte endast genom att sjÀlv följa hygienrutiner utan Àven genom att ge adekvat information till hÀstÀgare.Contagious diseases causes suffering for the affected individuals and may result in large economic consequences. Hence, an active approach for disease control and prevention has advantages both from an animal welfare perspective and an economic perspective. Three of the most important endemic diseases among horses in Sweden are equine influenza, equine herpesvirus-1 and strangles. All three diseases cause symptoms in the upper respiratory tract and a contagious nasal shedding. They spread directly from horse to horse and indirectly via contamination of the environment and people who are handling affected horses. Actions to prevent indirect contamination seem rare in Swedish stables, only a few stables offer facilities for washing their hands with warm water and soap.
Horses that are moved between different stables in relation to selling, breeding, training and competing constitute the greatest risk for the spread of contagious diseases. People that are moving between stables, for example veterinarians, also constitute a risk but there are preventive measures which limit the risk. Changing clothes between visits to different stables or using protective clothing, footbath at the entrance of the stable or providing boots for visitors are measures which haves proven useful in preventing a stable from infection. Moreover, washing hands in warm water and soap is effective in order to remove both bacteria and virus from hands. Some studies indicate that hand disinfection might be as effective or sometimes even more effective against the viruses and bacteria mentioned.
Many veterinarians state that they undertake a number of preventative measures between their visits to different farms. However, some studies show that it is difficult to make people follow biosecurity rules and many people have an inaccurate perception regarding whether or not they follow the rules.
How important the veterinarianâs biosecurity and hygiene are for the spread of infectious agents can be discussed. Many stables are visited by numbers of different persons during one day and the stablesâ own routines for biosecurity are probably more important than what the individual veterinarian does. However horse owners seem to have a high confidence in their own veterinarian according to biosecurity measures and the veterinarian may hence contribute to the infection control not only by following good routines for hygiene but also by giving adequate information to horse owners
Svenska och norska hÀstar med mugg och rasp
Mugg och rasp Àr ett vanligt förekommande hudproblem pÄ hÀst. Det Àr snarare ett syndrom Àn
en sjukdom dÄ benÀmningen mugg och rasp beskriver lesioner pÄ hÀstens distala ben. PÄ
engelska gĂ„r syndromet oftast under namnet âPastern dermatitisâ men fler benĂ€mningar kan
förekomma. Lesionerna kan bl.a. visa sig i form av krustor, sÄr och svullnader. Den drabbade
hÀsten kan bli halt och lesionerna kan leda till kroniska besvÀr. Det finns flera olika
underliggande orsaker finns till att mugg och rasp uppstÄr, bl.a. omnÀmns Chorioptes bovis,
Trombicula alfreddugesi, fotosensibilitet och vaskulit i litteraturen.
2017 inledde Statens veterinÀrmedicinska anstalt och Sveriges lantbruksuniversitet tillsammans
med Norges veterinÀrinstitut ett forskningsprojekt finansierat av Stiftelsen hÀstforskning. MÄlet
med projektet Àr att hitta bÀttre diagnostik och behandling för mugg och rasp. En del av
projektet bestÄr av en enkÀt som nÄtt svenska och norska hÀstÀgare och det Àr denna enkÀt som
detta arbete handlar om. FrÄgor som stÀlls Àr bland annat: Vilka symtom Àr vanliga? Vilka ben
drabbas? Spelar mÀngden hovskÀgg nÄgon roll för hur sjukdomsbilden ser ut? MÄlsÀttningen
med detta arbete Àr att kartlÀgga symtombild och sjukdomsförlopp vid mugg och rasp hos
nordiska hÀstar.
Resultatet av detta arbete bekrÀftar det som stÄr beskrivet i litteraturen om att bakben verkar
drabbas oftare Àn framben. HÀstar fÄr samma typ av symtom oavsett hur mycket behÄring de
har pÄ benen. De absolut vanligaste symtomen Àr krustor följt av sÄr, smÀrta, svullnad, klÄda
och hudvalkar. Det Àr vanligt förekommande med kroniska och/eller Äterkommande besvÀr.
Blött/lerigt vÀder Àr en försvÄrande omstÀndighet oavsett vilken typ av behÄring hÀsten har. Ett
intressant resultat Àr att hÀstar med tunnare behÄring i högre utstrÀckning drabbas sommartid
medan en del hÀstar med kraftigare behÄring snarare drabbas vintertid. Detta kan indikera att
beroende pÄ typ av behÄring Àr hÀsten mer eller mindre mottaglig för de olika underliggande
orsakerna till mugg och rasp. Bland de hÀstar som i högre grad insjuknar pÄ vintern finns en
stor representation av rasen nordsvensk brukshÀst och dölehÀst. Detta skulle kunna tyda pÄ att
det finns en genetisk faktor som gör dessa hÀstar mer mottagliga för underliggande orsaker som
Ă€r vanligare vintertid, t.ex. benskabb.Pastern dermatitis is a regularly occurring skin-problem in horses that affects the distal limbs.
The syndrome is also named greasy heel, cracked heel, scratches, mud fever, verrucous
pododermatitis and grapes. Crusts, wounds and swellings are typical symptoms. Lameness is
not an uncommon complication and the problems can get chronic. There are several underlying
reasons for pastern dermatitis described in the litterature, for example Chorioptes bovis,
Trombicula alfreduggesi, photosensitivity and vasculitis.
In 2017 a joint research project between National veterinary institute of Sweden, Swedish
university of veterinary sciences and the Norwegian veterinary institute, financed by The
Swedish-Norwegian Fund for Equine Research was launched. The projectâs goal is to identify
better diagnostic tools and treatments for pastern dermatitis. The project partly consists of a
survey addressed to horse owners in Sweden and Norway. The survey includes questions
concerning any eventual skin problems in the distal limbs of the horse, what limbs are affected
and what time of the year these problems occur. This thesis will study the answers of the survey.
Questions asked will be: What symptoms are common? Which legs are more often affected?
Does it matter whether the horse is feathered or non-feathered for how pastern dermatitis will
occur? The aim with this thesis is to map the symptoms and the disease course for pastern
dermatitis in Swedish and Norwegian horses.
The result of this thesis confirms what is earlier described in the literature, the hindlimbs are
more frequently affected than the forelimbs. The symptoms seem to be the same whether the
horse have feathered legs or not. The most common symptoms are crusts followed by wounds,
pain, swelling, pruritus and thickened skin. It is common with chronic and/or reoccurring
problems. Wet and muddy weather seems to make the problems worse for all types of horses.
An interesting finding is that non-feathered horses have more problems during summer while
some feathered horses have more problems during winter. This could indicate that pastern
dermatitis can be caused through different pathogenesis depending on what type of coat the
horse has. Among those horses that are more disposed during winter there is a large proportion
of Nordsvensk brukshÀst and DölehÀst. This could indicate that there is some genetic factor that
makes these horses more adoptive for the underlaying causes that are more common during the
winter, for example Chorioptes bovis
Properties of a novel radiophotoluminescent readout system using a cw modulated UV laser diode and phase-sensitive technique
Outbreak of Puumala Virus Infection, Sweden
An unexpected and large outbreak of Puumala virus infection in Sweden resulted in 313 nephropathia epidemica patients/100,000 persons in VĂ€sterbotten County during 2007. An increase in the rodent population, milder weather, and less snow cover probably contributed to the outbreak
First Human Isolate of Hantavirus (Andes virus) in the Americas
We isolated Andes virus (formal name: Andes virus [ANDV], a species in the genus Hantavirus), from serum of an asymptomatic 10-year-old Chilean boy who died 6 days later of hantavirus pulmonary syndrome (HPS). The serum was obtained 12 days after his grandmother died from HPS and 2 days before he became febrile. No hantavirus immunoglobulin (Ig) G or IgM antibodies were detected in the serum sample. After three blind passages, ANDV antigens were detected in Vero E6 cells by immunofluorescence assay and enzyme-linked immunosorbent assay, and ANDV RNA was detected by reverse transcription-polymerase chain reaction. A fragment of the virus genome showed 96.2% nucleotide identity with that of prototype ANDV. To our knowledge, this is the first isolation of any agent of hemorrhagic fever with renal syndrome from a human and the first such isolation of hantavirus before symptoms of that syndrome or HPS began
Human Hantavirus Infections, Sweden
The prevalent human hantavirus disease in Sweden is nephropathia epidemica, which is caused by Puumala virus and shed by infected bank voles (Clethrionomys glareolus). To evaluate temporal and spatial patterns of this disease, we studied 2,468 reported cases from a highly disease-endemic region in northern Sweden. We found that, in particular, middle-aged men living in rural dwellings near coastal areas were overrepresented. The case-patients were most often infected in late autumn, when engaged in activities near or within manmade rodent refuges. Of 862 case-patients confident about the site of virus exposure, 50% were concentrated within 5% of the study area. The incidence of nephropathia epidemica was significantly correlated with bank vole numbers within monitored rodent populations in part of the region. Understanding this relationship may help forestall future human hantavirus outbreaks
Demographic Factors Associated with Hantavirus Infection in Bank Voles (Clethrionomys glareolus)
The bank vole (Clethrionomys glareolus) is the natural reservoir of Puumala virus (PUUV), a species in the genus Hantavirus. PUUV is the etiologic agent of nephropathia epidemica, a mild form of hemorrhagic fever with renal syndrome. Factors that influence hantavirus transmission within host populations are not well understood. We evaluated a number of factors influencing on the association of increased PUUV infection in bank voles captured in a region in northern Sweden endemic for the virus. Logistic regression showed four factors that together correctly predicted 80% of the model outcome: age, body mass index, population phase during sampling (increase, peak, or decline/low), and gender. This analysis highlights the importance of population demography in the successful circulation of hantavirus. The chance of infection was greatest during the peak of the population cycle, implying that the likelihood of exposure to hantavirus increases with increasing population density
Background radiation and individual dosimetry in the costal area of Tamil Nadu, India.
South coast of India is known as the high-level background radiation area (HBRA) mainly due to beach sands that contain natural radionuclides as components of the mineral monazite. The rich deposit of monazite is unevenly distributed along the coastal belt of Tamil Nadu and Kerala. An HBRA site that laid in 2Ă7 m along the sea was found in the beach of Chinnavillai, Tamil Nadu, where the maximum ambient dose equivalent reached as high as 162.7 mSv y(-1). From the sands collected at the HBRA spot, the high-purity germanium semi-conductor detector identified six nuclides of thorium series, four nuclides of uranium series and two nuclides belonging to actinium series. The highest radioactivity observed was 43.7 Bq g(-1) of Th-228. The individual dose of five inhabitants in Chinnavillai, as measured by the radiophotoluminescence glass dosimetry system, demonstrated the average dose of 7.17 mSv y(-1) ranging from 2.79 to 14.17 mSv y(-1)
Human immunoglobulin G levels of viruses and associated glioma risk
Few consistent etiological factors have been identified for primary brain tumors. Inverse associations to asthma and low levels of varicella-zoster virus, immunoglobulin (Ig) levels in prevalent cases have indicted a role for the immune system in the development of glioma. Because samples from prevalent cases of glioma could be influenced by treatments such as steroids and chemotherapy, we investigated pre-diagnostic samples from three large Scandinavian cohorts. To test the hypothesis that immune response levels to these viruses are associated etiologically with glioma risk, we investigated pre-diagnostic immunoglobulin levels for cytomegalovirus (CMV), varicella-zoster virus (VZV), adenovirus (Ad), and Epstein-Barr virus (EBV) including the nuclear antigen (EBNA1) using plasma samples from 197 cases of adult glioma and 394 controls collected from population-based cohorts in Sweden and Denmark. Low VZV IgG levels were marginally significantly more common in glioma cases than the controls (odds ratio (OR) = 0.68, 95% CI 0.41â1.13) for the fourth compared with the first quartile (p = 0.06 for trend). These results were more prominent when analyzing cases with blood sampling at least 2 years before diagnosis (OR = 0.63, 95% CI 0.37â1.08) (p = 0.03). No association with glioma risk was observed for CMV, EBV, and adenovirus
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