445 research outputs found

    Rare Manifestations of Multiple Myeloma

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    Historia de la Colonia Alvear : (1901-1914)

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    La colonia Alvear, situada en el Sudeste de la Provincia de Mendoza fue fundada en 1901 por los sucesores de Diego de Alvear. Su creación no se puede considerar un hecho aislado sino que se enmarca en el proceso de avance de la frontera agroganadera hacia el sur del País y, en particular, en la ocupación del oasis Sur de Mendoza que se produjo entre fines del siglo XIX y la primera década del siglo XX. Fue un emprendimiento generado a partir de capitales foráneos con escasa intervención del Estado provincial. Su constitución estuvo determinada por los proyectos ferroviarios que se habían gestado en el país en la segunda mitad del siglo XIX y que pretendían unir el litoral atlántico con Chile.Alvear colony, located in the Southeast of the Province of Mendoza was founded in 1901 by the successors of Diego de Alvear. His creation can not be considered an isolated event but part of the process of advance of the agricultural and farming to the south of the country and, in particular, in the occupation of southern Mendoza oasis that occurred between the late nineteenth and first decade of the twentieth century. It was a venture capital generated from outsiders with little provincial government intervention. Its constitution was determined by the rail projects that were conceived in the country in the second half of the nineteenth century and sought to unite the Atlantic coast to Chile.Fil: Martínez Jurczyszyn, Carina. Universidad Nacional de Cuy

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    The article relates to a sense of coherence and styles of coping with stress in a group of students of medical and non-medical universities. In the first part, a brief characteristics of the specifics of studies and future student work from both types of universities were presented. The issue of a sense of coherence and coping with stress in research was approximated closer. The study used a life orientation questionnaire (SOC-29) examining the sense of coherence and a questionnaire of coping in stressful situations (CISS). The level of a sense of coherence and strategies to deal with stress from students from medical and non-medical universities were compared. With the use of SOC-29 and CISS questionnaires, a group of 145 people were examined. Among the respondents there were 72 students from medical universities and 73 students from non-medical universities. In a group of students from medical universities, it has been shown that the level of sense of coherence is significantly different from the level of sense of coherence of non-medical students. The style focused on emotions was most often used in both student groups. There is a relationship between a style focused on emotions and a sense of coherence. In the study groups, no relationship was shown between the style concentrated on avoidance and the sense of coherence. The level of sense of coherence of students from medical universities is significantly different from the level of sense of coherence of students from non-medical universities. Students from both universities most often use the style concentrated on emotions, less often task style. The style focused on emotions correlates at a high level with a sense of coherence. The style focused on avoidance does not correlate with a sense of coherence. A relationship between an emotional style of coping with stress and a low sense of coherence is visible

    “No” for the allogeneic stem cell transplantation in young patients diagnosed with multiple myeloma

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    Autologous stem cell transplantation (ASCT) is considered the standard of care in younger patients diagnosed with multiple myeloma (MM). However, despite an increase in the number of sustained responses, MM remains an incu­rable disease. Allogeneic stem cell transplantation (alloSCT) may have a curative potential resulting from induction of graft-versus-myeloma effect, but several factors limit its implementation in routine clinical practice. Myeloablative conditioning is associated with high (> 30%) treatment-related mortality (TRM), primarily due to graft-versus-host disease and infections, while the use of reduced-intensity conditioning increases the risk of relapse and disease progression, and also results in an unacceptably high TRM (21–23%). Auto/allotransplantation is not superior to tandem ASCT in terms of progression-free survival and overall survival, even in high-risk MM patients. The majority of younger patients may achieve sustained remissions after novel agents and ASCT, and nowadays alloSCT should be considered mainly in the context of clinical trials

    State of Oral Mucosa as an Additional Symptom in the Course of Primary Amyloidosis and Multiple Myeloma Disease

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    Multiple myeloma (myeloma multiplex (MM)) is a malignant non-Hodgkin’s lymphoma derived from B cell. Its essence is a malignant clone of plasma cells synthesizing growth of monoclonal immunoglobulin, which infiltrate the bone marrow, destroy the bone structure, and prevent the proper production of blood cells components. The paper presents a case of 62-year-old patient who developed symptoms in addition to neurological and haematological changes in the oral mucosa in the course of multiple myeloma. The treatment resulted in partial improvement. The authors wish to draw attention not only to nonspecificity and rarity of changes in the mouth which can meet the dentist but also to the complexity of the multidisciplinary therapy patients diagnosed with MM

    Ge-substitutional defects and the r3xr3 <--> 3x3 transition in alpha--SnGe(111)

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    The structure and energetics of Ge substitutional defects on the alpha-Sn/Ge(111) surface are analyzed using Density Functional Theory (DFT) molecular dynamics (MD) simulations. An isolated Ge defect induces a very local distortion of the 3x3 reconstruction, confined to a significant downwards displacement (-0.31 A) at the defect site and a modest upward displacement (0.05 A) of the three Sn nearest neighbours with partially occupied dangling bonds. Dynamical fluctuations between the two degenerate ground states yield the six-fold symmetry observed around a defect in the experiments at room temperature. Defect-defect interactions are controlled by the energetics of the deformation of the 3x3 structure: They are negligible for defects on the honeycomb lattice and quite large for a third defect on the hexagonal lattice, explaining the low temperature defect ordering.Comment: 4 pages, Revtex, 7 Encapsulated Postscript figures, uses epsf.sty. Submitted to Phys. Rev. Let

    Effects of fertilization and mulch treatment on growth and establishment of three seedling types of Norway spruce (Picea abies (L.)Karst.)

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    The effects of fertilization and mulch treatment on growth and establishment of three seedling types of Norway spruce [Picea abies (L.) Karst.] were examined in a study in southern Sweden. Three types of seedlings were used in the experiment: 2 years old hybrid seedlings (P+1, which means that during the first year the seedling is grown in a container and the second year grown in the field), 1,5 years old containerized seedlings and 10 weeks old mini seedlings. The seedlings were planted under near optimal conditions or in control parcels. Fertilization treatment was applied by a drip irrigation system and plastic cover mulch was used as weed control to create near optimal conditions. Growth and vitality of seedlings were compared between optimized and control parcels. Growth parameters were measured after one and two growing seasons. All seedling types were significantly affected by fertilization and mulch. Height and top increment was greater in fertilized plots compared to the control. Amount of biomass differed significantly between treatments after the second growing season. Nutrient content differed between treatments only after the first growing season

    Main functions of loud vocalization in populations of edible dormouse Glis glis

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    The study aimed to determine when, during summer activity, males and females of the edible dormouse most often used loud calls. On this basis, an attempt was made to determine the main purpose of the emission of these calls. It was assumed that 1) if males have the most of loud calls in July, their emissions may be related primarily to the mating behaviour (which takes place during this period), and if they have the most of loud calls in August, their emissions are most likely concerned defence of food resources, 2) in females, most of this vocalization would occur in August due to the need to defend their food resources and 3) in both sexes, more vocalization would occur in the year of good beech fruit crop (when the dormice would reproduce) than in the year of no crop (when the dormice would not reproduce). To check these assumptions, the number of loud calls and “performances” (series of loud calls) emitted by the animals from two wild populations tracked by telemetry was noted. The mean number of “performances” and loud calls in males and females was higher in August than in July (when beech fruits ripen), but significant differences were found only for “performances”. Both males and females had significantly more “performances” and loud calls in the mast/breeding year than in the non-mast/non-breeding year. It seems that males and females use loud calls mainly to defend important resources and are, therefore, most often heard during the mast year
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