Reseña. Hilda Sabato. Republics of the New World. The Revolutionary Political Experiment in Nineteenth-Century Latin America. (New Jersey: Princeton University Press, 2018)

En este compacto pero contundente libro, Hilda Sabato ofrece una primera gran síntesis de la renovación que vienen experimentando los estudios sobre la formación de Estados en América Latina, proceso que ella muy adecuadamente denomina un “experimento republicano”.  Lejos de las imágenes convencionales de un continente sumido en la barbarie primordial, en la anarquía postcolonial, o en una anomia caudillesca alimentada por la disolución institucional y la inmadurez ideológica, el libro da cuenta de una transición política no muy diferente de la que por esos mismos años experimentaban otros países del hemisferio occidental, habitualmente retratados como el paradigma de progreso que en nuestras latitudes se quiso, pero no se pudo, emular.

Discursos de clase en el ciclo salitrero: la construcción ideológica del sujeto obrero en Chile, 1890-1912

Centrándose en el período histórico en que comienza a cristalizar una identidad clasista entre los sectores populares chilenos, este artículo explora los «discursos de clase» que comienzan a circular en el mundo salitrero en el tránsito del siglo XIX al XX. Se postula que esos discursos, de sello obrerista, contribuyen a la construcción de una nueva autopercepción de estos actores como sujeto colectivo, proporcionando diversas claves de sentido que fueron formando parte del proceso de constitución de una clase obrera que se identificaba prioritariamente como tal. De allí, emergieron demandas de humanidad, de ciudadanía y, finalmente, de revolución, que marcarían los proyectos obreros durante lo que restaba del siglo XX

The Relevance of Digital Infographics in Online Newspapers

In the more developed societies online newspapers have already reached a very high degree of notoriety. The newspaper, besides being a product of the journalistic domain, is also the product of the visual domain. Due to the incorporation of new technologies and of different visual trends, substantial changes in consolidated models of newspaper design have been seen that originated a growth in the importance of the image that the newspaper has in the web. It was from this context that emerged the research described in this article. An analysis of the technique used in a specific aspect of the essential graphics in this model of communication: infographics, was carried out. To that purpose, a study of infographics in web journalism was performed, in order to determine its essencial elements

Early Cognitive/Social Deficits and Late Motor Phenotype in Conditional Wild-Type TDP-43 Transgenic Mice

Frontotemporal Dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two neurodegenerative diseases associated to mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43). To investigate in depth the behavioral phenotype associated with this proteinopathy, we used as a model transgenic (Tg) mice conditionally overexpressing human wild-type TDP 43 protein (hTDP-43-WT) in forebrain neurons. We previously characterized these mice at the neuropathological level and found progressive neurodegeneration and other features that evoke human TDP-43 proteinopathies of the FTD/ALS spectrum. In the present study we analyzed the behavior of mice at multiple domains, including motor, social and cognitive performance. Our results indicate that young hTDP-43-WT Tg mice (1 month after post-weaning transgene induction) present a normal motor phenotype compared to control littermates, as assessed by accelerated rotarod performance, spontaneous locomotor activity in the open field test and a mild degree of spasticity shown by a clasping phenotype. Analysis of social and cognitive behavior showed a rapid installment of deficits in social interaction, working memory (Y-maze test) and recognition memory (novel object recognition test) in the absence of overt motor abnormalities. To investigate if the motor phenotype worsen with age, we analyzed the behavior of mice after long-term (up to 12 months) transgene induction. Our results reveal a decreased performance on the rotarod test and in the hanging wire test, indicating a motor phenotype that was absent in younger mice. In addition, long-term hTDP-43-WT expression led to hyperlocomotion in the open field test. In sum, these results demonstrate a time-dependent emergence of a motor phenotype in older hTDP-43-WT Tg mice, recapitulating aspects of clinical FTD presentations with motor involvement in human patients, and providing a complementary animal model for studying TDP-43 proteinopathies.Fil: Alfieri, Julio Armando. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; ArgentinaFil: Silva Pinto, Pablo Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; ArgentinaFil: Müller Igaz, Lionel Ivan. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; Argentin

An imaging ethos?

An imaging ethos? — A possible correlation is made between Aristotelian rhetoric and Peirce’s semiotics in an attempt to apprehend the circulation of images in contemporary society as a device to create an ethos from symbolic contents (logos) that are constitutive of social arguments