Wireless Sensor Network Solution for Sustainable Food Production

Environmental monitoring has become a key aspect in food production over the last few years. Due to their low cost, low power consumption and flexibility, Wireless Sensor Networks (WSNs) have turned up as a very convenient tool to be used in these environments where no intrusion is a must. In this work, a WSN application in a food factory is presented. The paper gives an overview of the system set up, covering from the initial study of the parameters and sensors, to the hardware-software design and development needed for the final tests in the factory facilities

Survival analysis of productive life in Florida dairy goats using a Cox proportional hazards model

Longevity is an economically important trait, since extending the functional life of a doe would allow us to keep the most productive females in the herd as long as possible, and this could result in the increased profitability of dairy farms. Thus, the objectives of this study were to determine the most important factors that in-fluence the length of productive life (LPL) of female Florida goats and to estimate its genetic additive variance using a Cox proportional hazards model. The data consisted of 70,695 productive life records from 25,722 Florida females kidding between 2006 and 2020. A total of 19,495 does had completed their productive life while 6227 (24.2%) does had censored information. The pedigree contained information on 56,901 animals. The average censoring age and average failure age after first kidding for LPL were 36 and 47 months respectively. The model included, as time- independent effects, the age at first kidding and the interaction between herd, year and season of birth of the doe, and as time- dependent effects, the age at kidding, the interaction between herd, year and season of kidding, the within- herd class of milk production deviation, and the interaction between the lactation number and the stage of lactation. All fixed effects had a significant ef-fect on LPL (p< 0.05). Does with older ages at the first kidding and an earlier age at kidding were at higher risk of being culled. A large difference among herds was observed in terms of culling risk, which highlighted the importance of adequate management practices. Also, high- producing does were less likely to be culled. The estimate of the additive genetic variance was 1.844 (in genetic standard de-viation), with a heritability estimate of 0.58 ± 0.012. The results of this study are expected to contribute to the development of a genetic model for genetic evalua-tion of the length of the productive life of Spanish dairy goat breeds

The Spitzer c2d survey of large, nearby, interstellar clouds. X. The Chamaeleon II pre-main-sequence population as observed with IRAC and MIPS

We discuss the results from the combined IRAC and MIPS c2d Spitzer Legacy survey observations and complementary optical and NIR data of the Chamaeleon II (Cha II) dark cloud. We perform a census of the young population in an area of similar to 1.75 deg^(2) and study the spatial distribution and properties of the cloud members and candidate pre-main-sequence (PMS) objects and their circumstellar matter. Our census is complete down to the substellar regime (M approximate to 0.03 M☉). From the analysis of the volume density of the PMS objects and candidates we find two groups of objects with volume densities higher than 25 M☉ pc^(-3) and 5-10 members each. A multiplicity fraction of about 13% +/- 3% is observed for objects with separations 0.8" < θ < 6.0" (142-1065 AU). No evidence for variability between the two epochs of the c2d IRAC data set, Δt ~ 6 hr, is detected. We estimate a star formation efficiency of 1%-4%, consistent with the estimates for Taurus and Lupus, but lower than for Cha I. This might mean that different star formation activities in the Chamaeleon clouds reflect a different history of star formation. We also find that Cha II is turning some 6-7 M☉ into stars every Myr, which is low in comparison with the star formation rate in other c2d clouds. The disk fraction of 70%-80% that we estimate in Cha II is much higher than in other star-forming regions and indicates that the population in this cloud is dominated by objects with active accretion. Finally, the Cha II outflows are discussed; a new Herbig-Haro outflow, HH 939, driven by the classical T Tauri star Sz 50, has been discovered

Constitutive modeling of hot deformation of carbon steels in the intercritical zone

A previous constitutive modeling for single-phase steels is extended using the mixing law to predict the behavior of hot deformation in the dual phase ferritic-austenitic intercritical zone of Fe-C-Mn-Si alloys. Mixing law considers two phases instead one, so one phase formula was modified. The constant’s values used represents average values to the same conditions in austenitic and ferritic model. The amount of each phase is determined as function of temperature and chemical composition. The developed constitutive modeling is validated by comparing the theoretical stress-strain curves with experimental isothermal uniaxial compression tests of 1008 and 1035 carbon steels at different temperatures and strain rates. The compression tests were carried out in a dilatometer with the compression load at strain rate of 10-3, 10-2 and 10-1 s-1. A good agreement was obtained between the calculated and experimental results over different stages of deformation and hardening. Microstructural analysis was also carried out to relate the deformation results to the microstructure of the steels. Finally, a general constitutive equation has been proposed for hot deformation of steels in the intercritical zone.Peer ReviewedPostprint (published version

Comparison of the design and methodology of Phase 3 clinical trials of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) and dolutegravir-based dual therapy (DTG) in HIV: a systematic review of the literature

Introduction: Current recommended antiretroviral regimens include a combination of two (dual; DT) or three (triple; TT) antiretroviral drugs. This study aims to determine whether the quality of evidence from clinical trials of dolutegravir (dolutegravir/lamivudine [DTG/3TC] or dolutegravir/rilpivirine [DTG/RPV]) is methodologically comparable to that of clinical trials conducted with bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF). Areas covered: A systematic review of the medical literature was carried out in PubMed without date or language restrictions, following the PRISMA guidelines. All aspects of the methodological design of phase 3 randomized clinical trials (RCTs) of DT and TT, evaluated by the European Medicines Agency (registration trials), were reviewed. The quality of clinical trials was assessed using the Jadad scale. Expert opinion: The search identified 5, 3 and 2 phase 3 RCTs with BIC/FTC/TAF, DTG/3TC and DTG/RPV, respectively, that met the inclusion criteria. The designs would not be comparable due to differences in pre-randomization losses, blinding, patient recruitment, as well as differences in methodological quality, with the average score of the RCTs conducted with BIC/FTC/TAF, DTG/3TC and DTG/RPV being 4.2 (high quality), 3.0 (medium quality) and 3.0 (medium quality), respectively. Due to methodological differences between the BIC/FTC/TAF, DTG/3TC and DTG/RPV RCTs, the results of these are not comparable

Influence of shaking and viable cell numbers on microbial conjugated linoleic acid (CLA) production

info:eu-repo/semantics/publishedVersio

A Spitzer c2d Legacy Survey to Identify and Characterize Disks with Inner Dust Holes

Understanding how disks dissipate is essential to studies of planet formation. However, identifying exactly how dust and gas dissipates is complicated due to difficulty in finding objects clearly in the transition of losing their surrounding material. We use Spitzer IRS spectra to examine 35 photometrically-selected candidate cold disks (disks with large inner dust holes). The infrared spectra are supplemented with optical spectra to determine stellar and accretion properties and 1.3mm photometry to measure disk masses. Based on detailed SED modeling, we identify 15 new cold disks. The remaining 20 objects have IRS spectra that are consistent with disks without holes, disks that are observed close to edge-on, or stars with background emission. Based on these results, we determine reliable criteria for identifying disks with inner holes from Spitzer photometry and examine criteria already in the literature. Applying these criteria to the c2d surveyed star-forming regions gives a frequency of such objects of at least 4% and most likely of order 12% of the YSO population identified by Spitzer. We also examine the properties of these new cold disks in combination with cold disks from the literature. Hole sizes in this sample are generally smaller than for previously discovered disks and reflect a distribution in better agreement with exoplanet orbit radii. We find correlations between hole size and both disk and stellar masses. Silicate features, including crystalline features, are present in the overwhelming majority of the sample although 10 micron feature strength above the continuum declines for holes with radii larger than ~7 AU. In contrast, PAHs are only detected in 2 out of 15 sources. Only a quarter of the cold disk sample shows no signs of accretion, making it unlikely that photoevaporation is the dominant hole forming process in most cases.Comment: 24 pages, 18 figures and 8 tables. Fixed a typo in Table

Coenzyme Q10 and Cardiovascular Diseases

Coenzyme Q10 (CoQ10), which plays a key role in the electron transport chain by providing an adequate, efficient supply of energy, has another relevant function as an antioxidant, acting in mitochondria, other cell compartments, and plasma lipoproteins. CoQ10 deficiency is present in chronic and age-related diseases. In particular, in cardiovascular diseases (CVDs), there is a reduced bioavailability of CoQ10 since statins, one of the most common lipid-lowering drugs, inhibit the common pathway shared by CoQ10 endogenous biosynthesis and cholesterol biosynthesis. Different clinical trials have analyzed the effect of CoQ10 supplementation as a treatment to ameliorate these deficiencies in the context of CVDs. In this review, we focus on recent advances in CoQ10 supplementation and the clinical implications in the reduction of cardiovascular risk factors (such as lipid and lipoprotein levels, blood pressure, or endothelial function) as well as in a therapeutic approach for the reduction of the clinical complications of CVD

COVID-19 pandemic on coronary artery and cerebrovascular diseases in Southern Spain: interrupted time series analysis

OBJECTIVE: Healthcare systems have been put under intense pressure by the COVID-19 pandemic, although some studies have shown a decline in hospital admissions for cardiovascular and cerebrovascular diseases during the first and second wave of the pandemic. In addition, studies analyzing gender and procedural differences are scarce. The present study aimed to determine the impact of the pandemic on hospital admissions for acute myocardial infarction (AMI) and cerebrovascular disease (CVD) in Andalusia (Spain) and analyzed differences by gender and by percutaneous coronary interventions performed. PATIENTS AND METHODS: An interrupted time series analysis of AMI and CVD hospital admissions in Andalusia (Spain) was carried out to measure the impact of the COVID-19 outbreak. AMI and CVD cases admitted daily in public hospitals of Andalusia between January 2018 and December 2020 were included. RESULTS: During the pandemic, significant reductions in AMI [-19%; 95% confidence interval (CI): (-29%, -9%), p<0.001] and CVD [-17%; 95% CI: (-26%, -9%); p<0.01] in daily hospital admissions were observed. Differences were also produced according to the diagnosis (ST-Elevation Myocardial Infarction, Non-ST-Elevation Myocardial Infarction, other AMI and stroke), with a greater reduction in females for AMI and in males for CVD. Although there were more percutaneous coronary interventions during the pandemic, no significant reductions were observed