Those good old days back home

https://digitalcommons.library.umaine.edu/mmb-vp/3393/thumbnail.jp

I\u27m Goin\u27 To Settle Down Outside Of London Town : When I\u27m Dry, Dry, Dry

https://digitalcommons.library.umaine.edu/mmb-vp/1784/thumbnail.jp

I\u27m Crying Just For You

https://digitalcommons.library.umaine.edu/mmb-vp/1777/thumbnail.jp

If We Can\u27t Be the Same Old Sweethearts We\u27ll Just Be the Same Old Friends

VERSE 1Once we were sweethearts,Not so long ago,Then I loved you so,But you didn’t know;You couldn’t learn to love me,You’re not to blame,But I like you just the same; CHORUSIf we can’t be the same old sweethearts,Then we’ll just be the same old friends,For I want someone like you,Just to tell my troubles to,My happiness on you it all depends;For I’ve know you too long to forget you,And my old dream of love never ends,Tho’ I know you can’t be mine,We will meet from time to time,And we’ll just be the same old friends.If we friends. VERSE 2You said you loved me,Not so long ago,But you didn’t know,Sweethearts come and go;Some day you’ll love another,And later on,You may want me, when he’s gone; CHORU

If I Had Some One Like You At Home : I Wouldn\u27t Want To Go Out

https://digitalcommons.library.umaine.edu/mmb-vp/5567/thumbnail.jp

Beatrice Fairfax, Tell Me What To Do!

https://digitalcommons.library.umaine.edu/mmb-vp/1079/thumbnail.jp

Sensory Feedback, Error Correction, and Remapping in a Multiple Oscillator Model of Place-Cell Activity

Mammals navigate by integrating self-motion signals (“path integration”) and occasionally fixing on familiar environmental landmarks. The rat hippocampus is a model system of spatial representation in which place cells are thought to integrate both sensory and spatial information from entorhinal cortex. The localized firing fields of hippocampal place cells and entorhinal grid-cells demonstrate a phase relationship with the local theta (6–10 Hz) rhythm that may be a temporal signature of path integration. However, encoding self-motion in the phase of theta oscillations requires high temporal precision and is susceptible to idiothetic noise, neuronal variability, and a changing environment. We present a model based on oscillatory interference theory, previously studied in the context of grid cells, in which transient temporal synchronization among a pool of path-integrating theta oscillators produces hippocampal-like place fields. We hypothesize that a spatiotemporally extended sensory interaction with external cues modulates feedback to the theta oscillators. We implement a form of this cue-driven feedback and show that it can retrieve fixed points in the phase code of position. A single cue can smoothly reset oscillator phases to correct for both systematic errors and continuous noise in path integration. Further, simulations in which local and global cues are rotated against each other reveal a phase-code mechanism in which conflicting cue arrangements can reproduce experimentally observed distributions of “partial remapping” responses. This abstract model demonstrates that phase-code feedback can provide stability to the temporal coding of position during navigation and may contribute to the context-dependence of hippocampal spatial representations. While the anatomical substrates of these processes have not been fully characterized, our findings suggest several signatures that can be evaluated in future experiments

Innate immunity and monocyte-macrophage activation in atherosclerosis

Innate inflammation is a hallmark of both experimental and human atherosclerosis. The predominant innate immune cell in the atherosclerotic plaque is the monocyte-macrophage. The behaviour of this cell type within the plaque is heterogeneous and depends on the recruitment of diverse monocyte subsets. Furthermore, the plaque microenvironment offers polarisation and activation signals which impact on phenotype. Microenvironmental signals are sensed through pattern recognition receptors, including toll-like and NOD-like receptors - the latter of which are components of the inflammasome - thus dictating macrophage behaviour and outcome in atherosclerosis. Recently cholesterol crystals and modified lipoproteins have been recognised as able to directly engage these pattern recognition receptors. The convergent role of such pathways in terms of macrophage activation is discussed in this review

The impact of TP-AGB stars on hierarchical galaxy formation models

The spectro-photometric properties of galaxies in galaxy formation models are obtained by combining the predicted history of star formation and mass accretion with the physics of stellar evolution through stellar population models. In the recent literature, significant differences have emerged regarding the implementation of the Thermally-Pulsing Asymptotic Giant Branch phase of stellar evolution. The emission in the TP-AGB phase dominates the bolometric and near-IR spectrum of intermediate-age (~1 Gyr) stellar populations, hence it is crucial for the correct modeling of the galaxy luminosities and colours. In this paper for the first time, we incorporate a full prescription of the TP-AGB phase in a semi-analytic model of galaxy formation. We find that the inclusion of the TP-AGB in the model spectra dramatically alters the predicted colour-magnitude relation and its evolution with redshift. When the TP-AGB phase is active, the rest-frame V-K galaxy colours are redder by almost 2 magnitudes in the redshift range z~2-3 and by 1 magnitude at z~1. Very red colours are produced in disk galaxies, so that the V-K colour distributions of disk and spheroids are virtually undistinguishable at low redshifts. We also find that the galaxy K-band emission is more than 1 magnitude higher in the range z~1-3. This may alleviate the difficulties met by the hierarchical clustering scenario in predicting the red galaxy population at high redshifts. The comparison between simulations and observations have to be revisited in the light of our results.Comment: 6 pages, 4 figures. Accepted for publication on MNRAS Letter