Isotopic study of the influence of oxygen interaction and surface species over different catalysts on the soot removal mechanism

In order to improve the catalytic formulations for soot removal in after-treatment emission control technologies for gasoline and diesel engine vehicle, an isotopic study was approached using transitory labeled oxygen response method over model catalysts that allows the unraveling of soot oxidation mechanism. Ce-based materials promote oxygen exchange associated with the high population of lattice oxygen species (O2-) denoted as OI type. The incorporation of praseodymium produces a Pr3+ enrichment that decrease the energy for oxygen release and increase oxygen mobility through surface and subsurface oxygen centers (OII type) depending on the synthesis procedure. For PtBaK catalyst, OIII species are responsible for oxygen exchange. Gas-solid reaction between soot and gas phase molecular oxygen is responsible for direct uncatalyzed soot oxidation. For ceria containing catalysts, low-temperature soot removal takes place through the intervention of lattice atomic species and superoxide species. For DPNR model catalyst, PtBaK/Al2O3, the soot elimination occurs with the intervention of OIII type centers. In the presence NO, the assisted and cooperative mechanism due to NO2 and the intervention of the adsorbed nitrate species on the trimetallic catalyst enhances soot removal capacity.MCR acknowledges the postdoctoral fellowship obtained from the University of Malaga. MCR, CH, MAL and LJA want to thank the financial support of CTQ 2017-87909R project. MCR also want to thank the University of Alicante for the financial support for the internship (INV19-07). JCMM and AGG gratefully acknowledge the financial support of Generalitat Valenciana (PROMETEO/2018/076 project) and the Spanish Ministry of Science, Innovation and Universities (PID2019-105542RB-I00 project) and the UE-FEDER funding. JCMM also acknowledges Spanish Ministry of Science, Innovation and Universities for the financial support through a FPU grant (FPU17/00603)

Characterizing diagnostic inertia in arterial hypertension with a gender perspective in primary care

Background and Objectives: Substantial evidence shows that diagnostic inertia leads to failure to achieve screening and diagnosis objectives for arterial hypertension (AHT). In addition, different studies suggest that the results may differ between men and women. This study aimed to evaluate the differences in diagnostic inertia in women and men attending public primary care centers, to identify potential gender biases in the clinical management of AHT. Study Design/Materials and methods: Cross-sectional descriptive and analytical estimates were obtained nested on an epidemiological ambispective cohort study of patients aged ≥30 years who attended public primary care centers in a Spanish region in the period 2008-2012, belonging to the ESCARVAL-RISK cohort. We applied a consistent operational definition of diagnostic inertia to a registry- reflected population group of 44,221 patients with diagnosed hypertension or meeting the criteria for diagnosis (51.2% women), with a mean age of 63.4 years (62.4 years in men and 64.4 years in women). Results: Of the total population, 95.5% had a diagnosis of hypertension registered in their electronic health record. Another 1,968 patients met the inclusion criteria for diagnostic inertia of hypertension, representing 4.5% of the total population (5% of men and 3.9% of women). The factors significantly associated with inertia were younger age, normal body mass index, elevated total cholesterol, coexistence of diabetes and dyslipidemia, and treatment with oral antidiabetic drugs. Lower inertia was associated with age over 50 years, higher body mass index, normal total cholesterol, no diabetes or dyslipidemia, and treatment with lipid-lowering, antiplatelet, and anticoagulant drugs. The only gender difference in the association of factors with diagnostic inertia was found in waist circumference. Conclusion: In the ESCARVAL-RISK study population presenting registered AHT or meeting the functional dia

Non-productive angiogenesis disassembles Aß plaque-associated blood vessels

The human Alzheimer’s disease (AD) brain accumulates angiogenic markers but paradoxically, the cerebral microvasculature is reduced around Aß plaques. Here we demonstrate that angiogenesis is started near Aß plaques in both AD mouse models and human AD samples. However, endothelial cells express the molecular signature of non-productive angiogenesis (NPA) and accumulate, around Aß plaques, a tip cell marker and IB4 reactive vascular anomalies with reduced NOTCH activity. Notably, NPA induction by endothelial loss of presenilin, whose mutations cause familial AD and which activity has been shown to decrease with age, produced a similar vascular phenotype in the absence of Aß pathology. We also show that Aß plaque-associated NPA locally disassembles blood vessels, leaving behind vascular scars, and that microglial phagocytosis contributes to the local loss of endothelial cells. These results define the role of NPA and microglia in local blood vessel disassembly and highlight the vascular component of presenilin loss of function in AD

Determinant Factors of Satisfaction in the Relationship between First- and Second-Order Agricultural Cooperatives

The integration in second-order cooperatives allows the first-order agricultural cooperatives to complement their resources and capabilities, achieving a sustainable competitive advantage. The problems associated with the creation, development and long-term maintenance of these partnerships, along with the lack of research into this area, justify the realization of studies aimed at improving our understanding of the processes and outcomes that characterize them. Therefore, the purpose of this study is to discover the factors which lead to the success of these relationships, empirically measured through the satisfaction of first-order co-operatives with the relationship. In order to achieve this, a suitable theoretical framework is established and an empirical study undertaken, with information obtained from a survey of 190 Spanish first-order agricultural co-operatives. The results obtained reveal that the contribution of the partnership to the first-order cooperative's performance, its trust and perception of fairness are critical antecedents of the level of satisfaction of the first-order cooperative satisfaction with the relationship

The joint impact of quality and innovativeness on short-term new product performance ☆

In the last decade a number of conceptualizations of product quality and innovativeness have been suggested, and academics as well as managers have begun to understand that the relationships between quality, innovativeness and new product performance are more complicated than they may initially seem to be. While an innovation-oriented strategy depends on the exploration of new possibilities through search, risk-taking and experimentation, a high quality strategy requires the exploitation of existing certainties through efficiency, standardization and control. In this research, we demonstrate that the interaction effects of quality (objective and subjective) and innovativeness (for the firm and for the customer) on new product performance are different than the isolated impact of these variables. In addition, by focusing on the main and joint impact of these variables on short-term new product performance, we provide valuable recommendations for new product launch decisions. "The pure and simple truth is rarely pure and never simple."-Oscar Wild

Determinant Factors of Satisfaction in the Relationship between First- and Second-Order Agricultural Cooperatives

The integration in second-order cooperatives allows the first-order agricultural cooperatives to complement their resources and capabilities, achieving a sustainable competitive advantage. The problems associated with the creation, development and long-term maintenance of these partnerships, along with the lack of research into this area, justify the realization of studies aimed at improving our understanding of the processes and outcomes that characterize them. Therefore, the purpose of this study is to discover the factors which lead to the success of these relationships, empirically measured through the satisfaction of first-order co-operatives with the relationship. In order to achieve this, a suitable theoretical framework is established and an empirical study undertaken, with information obtained from a survey of 190 Spanish first-order agricultural co-operatives. The results obtained reveal that the contribution of the partnership to the first-order cooperative's performance, its trust and perception of fairness are critical antecedents of the level of satisfaction of the first-order cooperative satisfaction with the relationship.Agricultural marketing, first- and second-order agricultural co-operatives, satisfaction, success factors of interorganizational relationships, Agribusiness,