1,002 research outputs found

    TFF (v.4.1): A Mathematica Notebook for the Calculation of One- and Two-Neutron Stripping and Pick-Up Nuclear Reactions

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    The program TFF calculates stripping single-particle form factors for one-neutron transfer in prior representation with appropriate perturbative treatment of recoil. Coupled equations are then integrated along a semiclassical trajectory to obtain one- and two-neutron transfer amplitudes and probabilities within first- and second-order perturbation theory. Total and differential cross-sections are then calculated by folding with a transmission function (obtained from a phenomenological imaginary absorption potential). The program description, user instructions and examples are discussed

    Health-related quality of life in outpatients with COPD in daily practice: the VICE Spanish study

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    Antonio Martín1, José M Rodríguez-González Moro2, José L Izquierdo3, Elena Gobartt4, Pilar de Lucas2, The VICE Study Group1Medical Department, Pfizer, Madrid, Spain; 2Service of Pneumology, HGU Gregorio Marañón, Madrid, Spain; 3Service of Pneumology, Hospital General Universitario de Guadalajara, Guadalajara, Spain; 4Respiratory Area, Medical Department, Boehringer Ingelheim España, Madrid, SpainBackground: The objective of this study was to measure health-related quality of life (HRQL) in outpatients with chronic obstructive pulmonary disease (COPD) and to assess differences in HRQL according to age, gender, and severity of COPD.Methods: A total of 9405 patients (79% men, mean age 68 years) participated in a cross-sectional study. HRQL was measured with the Short Form 12 Health Survey Questionnaire (SF-12). Severity of COPD was graded into three levels according to forced expiratory volume in one second value.Results: COPD severity was mild in 33.8% of cases, moderate in 49.3% and severe in 16.8%. The mean physical component summary (PCS-12) and mental component summary (MCS-12) scores were 36.8 ± 10.4 and 47.2 ± 11.2, respectively. General health and physical functioning domains were those with the lowest scores. The mean MCS-12 scores were significantly higher in men (47.9 ± 10.9) than in women (44.1 ± 11.8) (P < 0.001). Patients older than 60 years rated HRQL worse than patients aged 40–59 years. There were statistically significant differences according to severity of disease in the mean scores of all domains of the PCS-12 and MCS-12 scales.Conclusions: The present findings show the influence of female gender, older age and moderate-to-severe of airflow limitation on HRQL in outpatients with COPD attended in daily practice.Keywords: health status, health surveys, multicenter study, pulmonary disease, chronic obstructive/epidemiology, quality of life, questionnaire

    Seis representaciones arquet?picas precolombinas (correspondencias con la narrativa hispanoamericana contempor?nea y creaci?n de minicuento)

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    175 p. Recurso Electr?nicoLa presente investigaci?n compila un corpus de representaciones arquet?picas a la luz de la teor?a sobre el inconsciente colectivo y los arquetipos planteados por Carl Gustav Jung. La configuraci?n de las representaciones fue realizada con mitos precolombinos, posterior a ello, a trav?s del m?todo de Gilbert Durand, denominado mitocr?tica, se comprob? la vigencia de las representaciones en cuentos de autores hispanoamericanos. As? mismo, se dise?? una unidad did?ctica para trasformar la ense?anza del mito en el grado noveno de la Instituci?n Educativa Alberto Castilla, con el fin de ampliar desde la teor?a de Mircea Eliade y de Carl Jung el concepto de mito, y el corpus de relatos le?dos por los estudiantes, para poder descubrir las convergencias arquet?picas, los atributos simb?licos y el car?cter sagrado que demuestran la relaci?n vigente entre mito y hombre. Finalmente, los estudiantes tuvieron la oportunidad de actualizar mitos, arquetipos y representaciones, mediante un proceso de escritura de minicuentos a trav?s del taller como espacio de aprendizaje, juego y creaci?n. Palabras Claves: Mito, Arquetipo, Mitocr?tica, Minicuento.The present investigation, compiles a corpus of representations archetypical in the light of theory about the collective unconscious and the archeotype raised by Carls Gustav Jung. The configuration of the representations were presented with pre-columbian myths, subsequently to it through the method of Gilbert Duran called mitochritic, was verified the validity of the representation in the stories of Hispanic -American authors. Likewise, a didactic unit was designed to transform the teaching of myth in the ninth grade of the educational institution Alberto Castilla, in order to expand from the theory of Mircea Eliade and of Carl Jung the concept of myth, and the corpus of stories read by the students, in order to discover the archetypal convergences, the symbolic attributes and the sacred character that demonstrates the current relationship between myth and man. Finally the students had the opportunity to update myths, archetypes and representations, through a process of writing mini-stories through the workshop as a space for learning, play and creation. Keywords: Myth, Archetype, Mitocritical, Mini-stories

    Estrategias de marketing digital y su relaci?n con la decisi?n de compra

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    En el presente estudi? se investig? la relaci?n entre las estrategias de marketing digital y la decisi?n de compra a trav?s de internet, por lo que en el presente estudio se tiene como finalidad demostrar que tan decisiva es esa relaci?n entre ambas variables. Se utiliz? una encuesta para recabar los datos necesarios y mediante el uso de herramientas estad?sticas se pudo obtener resultados que muestran esta relaci?n. Dentro de estos resultados se observa que existen una relaci?n entre las estrategias de marketing digital y dos factores de la decisi?n de compra, mientras que otros dos factores no guardan relaci?n debido que no depende del consumidor por un tema de segmentaci?n que las empresas deben realizar. Para concluir con la investigaci?n se observa una relaci?n significativa entre ambas variables y como uno de los factores puede tener una mayor influencia que otra

    Heavy metal tolerance strategies in metallicolous and non-metallicolous populations of mosses: Insights of γ+β-tocopherol regulatory role

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    As bryophytes present the capacity to colonize a wide range of habitats, including extreme environments (e.g., mine areas), we first checked the global response of bryophytes to heavy metals (HM) by a systematic review. This analysis found i) the lack of studies in a polluted environment and ii) resulted in a global trend of photochemical efficiency decrease when bryophytes faced heavy metals. Secondly, we characterized the photoprotective responses of four metallicolous populations of mosses (Lewinskya rupestris, Polytrichum commune, Ptychostomum compactum and Rhynchostegium confertum) naturally growing in an abandoned mine area by an experimental field approach. As a result, we found markedly species-specific tolerance patterns: i) less tolerant species, presenting high pollutants content accompanied by marked dissipative and antioxidative strategies. This strategy was depicted by the species R. confertum that result to be a good sentinel species due to the high pollutant content and high physiological sensitivity.; ii) intermediate tolerant species presenting a medium content of pollutants and less marked photoprotective mechanisms, and iii) most tolerant species minimizing pollutants content and consequently presenting no changes in their physiological performance. This evidence support that species’ bryological attributes have a key role in determining species’ tolerance towards environmental heavy metals, and should be taken into consideration in future studies. The findings of this study also pointed out that the higher levels of γ + β-tocopherol in metallicolous populations could play a regulatory role in metal stress tolerance in mosses and it could be a suitable functional responsive trait for environmental response prediction to heavy metals in polluted environments

    Potential Oestrogenic Effects (Following the OECD Test Guideline 440) and Thyroid Dysfunction Induced by Pure Cyanotoxins (Microcystin-LR, Cylindrospermopsin) in Rats

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    Potential endocrine-disrupting properties of cyanotoxins, such as microcystin-LR (MC-LR) and cylindrospermopsin (CYN) are of concern due to their increasing occurrence, the scarcity of reports on the topic (particularly for CYN) and the impact of human's health at different levels. Thus, this work performed for the first time the uterotrophic bioassay in rats, following the Organization for Economic Cooperation and Development (OECD) Test Guideline 440, to explore the oestrogenic properties of CYN and MC-LR (75, 150, 300 μg/kg b.w./day) in ovariectomized (OVX) rats. Results revealed neither changes in the wet and blotted uterus weights nor in the morphometric study of uteri. Moreover, among the steroid hormones analysed in serum, the most remarkable effect was the dose-dependent increase in progesterone (P) levels in rats exposed to MC-LR. Additionally, a histopathology study of thyroids and serum levels of thyroids hormones were determined. Tissue affectation (follicular hypertrophy, exfoliated epithelium, hyperplasia) was observed, as well as increased T3 and T4 levels in rats exposed to both toxins. Taken together, these results point out that CYN and MC-LR are not oestrogenic compounds at the conditions tested in the uterotrophic assay in OVX rats, but, however, thyroid disruption effects cannot be discarded.Ministerio de Ciencia e Innovación PRE 2020-094412Junta de Andalucía P18-RTJ-195
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