An Experimental Review on Deep Learning Architectures for Time Series Forecasting

In recent years, deep learning techniques have outperformed traditional models in many machine learning tasks. Deep neural networks have successfully been applied to address time series forecasting problems, which is a very important topic in data mining. They have proved to be an effective solution given their capacity to automatically learn the temporal dependencies present in time series. However, selecting the most convenient type of deep neural network and its parametrization is a complex task that requires considerable expertise. Therefore, there is a need for deeper studies on the suitability of all existing architectures for different forecasting tasks. In this work, we face two main challenges: a comprehensive review of the latest works using deep learning for time series forecasting; and an experimental study comparing the performance of the most popular architectures. The comparison involves a thorough analysis of seven types of deep learning models in terms of accuracy and efficiency. We evaluate the rankings and distribution of results obtained with the proposed models under many different architecture configurations and training hyperparameters. The datasets used comprise more than 50000 time series divided into 12 different forecasting problems. By training more than 38000 models on these data, we provide the most extensive deep learning study for time series forecasting. Among all studied models, the results show that long short-term memory (LSTM) and convolutional networks (CNN) are the best alternatives, with LSTMs obtaining the most accurate forecasts. CNNs achieve comparable performance with less variability of results under different parameter configurations, while also being more efficient

Valorization of Tomato Processing by-Products: Fatty Acid Extraction and Production of Bio-Based Materials

A method consisting of the alkaline hydrolysis of tomato pomace by-products has been optimized to obtain a mixture of unsaturated and polyhydroxylated fatty acids as well as a non-hydrolysable secondary residue. Reaction rates and the activation energy of the hydrolysis were calculated to reduce costs associated with chemicals and energy consumption. Lipid and non-hydrolysable fractions were chemically (infrared (IR) spectroscopy, gas chromatography/mass spectrometry (GC-MS)) and thermally (differential scanning calorimetry (DSC), thermogravimetric analysis (TGA)) characterized. In addition, the fatty acid mixture was used to produce cutin-based polyesters. Freestanding films were prepared by non-catalyzed melt-polycondensation and characterized by Attenuated Total Reflected-Fourier Transform Infrared (ATR-FTIR) spectroscopy, solid-state nuclear magnetic resonance (NMR), DSC, TGA, Water Contact Angles (WCA), and tensile tests. These bio-based polymers were hydrophobic, insoluble, infusible, and thermally stable, their physical properties being tunable by controlling the presence of unsaturated fatty acids and oxygen in the reaction. The participation of an oxidative crosslinking side reaction is proposed to be responsible for such modifications.Andalusian Regional Government P11-TEP-7418Spanish Ministerio de Economía y Competitividad AGL2015-65246-R and AGL2017-83036-RFondo Europeo de Desarrollo Regional (FEDER) AGL2015-65246-R and AGL2017-83036-

Estudio de digénidos de peces marinos del sur de la Península Ibérica

Se han estudiado un total de 492 hospedadores pertenecientes a 72 especies de peces marinos, todos procedentes de la plataforma continental que bordea el sur de la Península Ibérica. Como resultado de este trabajo se han localizado en el aparato digestivo de estos hospedadores 39 especies de Digenea. De ellas, Stephanostomum bicoronatum, (Stossich, 1883) Manter, 1940, Parahemiurus merus, (Linton, 1910) Manter, 1940, Derogenes latus Janiszewska, 1953, Bacciger israelensis Fischtha1, 1980, Promnoprymna ventricosa (Rudolphi, 1819) Poche, 1926, Haploporus benedenii (Stossich, 1887) Looss, 1902, Haplosplanchnus pachysomus (Eysenhardt, 1829) Looss, 1902, Saccocoelium obesum Looss, 1902, y Genolopa ampullacea Linton, 1910 se citan por primera vez en la península Ibérica. Lecithochirium musculus (Looss, 1907) Nasir y Díaz, 1971, Lecithochirium rufoviride (Rudolphi, 1819) Lühe, 1901, Lecithochirium fusiforme Lühe, 1901, Ectenurus lepidus Looss, 1907 y Tergestia laticollis (Rudolphi, 1819) Stossich, 1899, en las costas de Andalucia. Stephanostomum minutum en el Mediterráneo peninsular. Wardulla capitel/ata (Rudolphi, 1819) Poche, 1926 y Deropristis inflata en el Atlántico peninsular. Además, con el presente trabajo se amplía considerablemente el espectro de hospedadores de algunas de las especies parásitas estudiadas. Así Halobatrachus didactylus es nuevo hospedador para Stephanostomum minutum (Looss, 1901) Manter, 1940, Anisocladium fallax (Rudolphi, 1819) Looss, 1902 y Anisocoelium capitellatum (Rudolphi, 1819) Lühe, 1900. Bothus podas para Lecithocladium excisum (Rudolphi, 1819) Lühe, 1901 y Derogenes varicus (Müller, 1784) Looss, 1901. Solea sp. para Lecithochirium musculus (Looss, 1907) Nasir y Díaz, 1971. Trachinotus ovatus para Synaptobothrium caudiporum (Rudolphi, 1819) Looss, 1907. Scorpaena scrofa para Derogenes latus Janiszewska, 1953. Belone belone para Tergestia laticollis (Rudolphi, 1819) Stossich, 1899. Dicentrarchus punctatus para Acanthostomum imbutiforme (Molin, 1859) Gohar, 1934 y Bucephalus baeri Maillard, 1976. y Echiichthys vipera para Anisocladiumfallax (Rudolphi, 1819) Looss, 1902 y Anisocoelium capitellatum (Rudolphi, 1819) Lühe, 1900A total of 492 host of72 diferent species ofmarine fishes were colleted from the Sourth Iberian Peninsula coast and their tract digest were examined. We have identified 39 species ofDigenea. Stephanostomum bicoronatum, (Stossich, 1883) Manter, 1940, Parahemiurus merus, (Linton, 1910) Manter, 1940, Derogenes latus Janiszewska, 1953, Bacciger israelensis Fischthal, 1980, Promnoprymna ventricosa (Rudolphi, 1819) Po che, 1926, Haploporus benedenii (Stossich, 1887) Looss, 1902, Haplosplanchnus pachysomus (Eysenhardt, 1829) Looss, 1902, Saccocoelium obesum Looss, 1902, and Genolopa ampullacea Linton, 1910, have not previously been reported from Iberian Peninsula. Furthermore, Lecithochirium musculus (Looss, 1907) Nasir y Díaz, 1971, Lecithochirium rufoviride (Rudolphi, 1819) Lühe, 1901, Lecithochirium fusiforme Lühe, 1901, Ectenurus lepidus Looss, 1907 and Tergestia laticollis (Rudolphi, 1819) Stossich, 1899, are reported for the first time in Andalucian coast; Stephanostomum minutum in the spanish mediterranean coast and finally, Wardulla capitellata (Rudolphi, 1819) Poche, 1926 and Deropristis inflata in the Atlántic peninsular. In this paper, we have thoroughly widened the host range for sorne of the species here studied. So, Halobatrachus didactylus is a new host for Stephanostomum minutum (Looss, 1901) Manter, 1940, Anisocladiumfallax (Rudolphi, 1819) Looss, 1902 and Anisocoelium capitellatum (Rudolphi, 1819) Lühe, 1900. Bothus podas for Lecithocladium excisum (Rudolphi, 1819) Lühe, 1901 and Derogenes varicus (Müller, 1784) Looss, 1901. Solea sp. for Lecithochirium musculus (Looss, 1907) Nasir y Díaz, 1971. Trachinotus ova tus for Synaptobothrium caudiporum (Rudolphi, 1819) Looss, 1907. Scorpaena scrofa for Derogenes latus Janiszewska, 1953. Belone belone for Tergestia laticollis (Rudolphi, 1819) Stossich, 1899. Dicentrarchus punctatus for Acanthostomum imbutiforme (Molin, 1859) Gohar, 1934 and Bucephalus baeri Maillard, 1976. Echiichthys vipera for Anisocladiumfallax (Rudolphi, 1819) Looss, 1902 andAnisocoelium capitellatum (Rudolphi, 1819) Lühe, 190

An application of the SMS method for imaging designs.

The Simultaneous Multiple Surface (SMS) method in planar geometry (2D) is applied to imaging designs, generating lenses that compare well with aplanatic designs. When the merit function utilizes image quality over the entire field (not just paraxial), the SMS strategy is superior. In fact, the traditional aplanatic approach is actually a particular case of the SMS strateg

Flebotomos de las Islas Canarias (España)

La ausencla de datos acerca de la fauna de Phlebotominae en el archiplelago Canario, nos ha llevado B realizar iiltimnmente varlos muestreos en las lslas de Oran Canaria y Tenerlfe. Para los mencionados muestreos se emple6 siempre la técnica del papel adhesivo. En Oran Canaria. de un total de €dete estaciones, s610 hubo capturas en una de ellas En Tenerife se recolectaron ejemplares en un total de slete estaciones pero el numero de capturas fue muy bajo. Los caracteres de los ejemplares machos y hembras capturados son : Macho: Pompa genltal en el tercer Segmento abdominal. Filamentos genitales muy largos, que sobrepasan las valvas del pene. Estas son troncoc6nicas con prolongaci6n basa1 muy desarrollada de aspecto semilunar. El estilo (con cinco esplnasi, coxito y l6bulo lateral no presentan particularidad notable. Hembra: Faringe con tres zonas definidas: la posterior, más ancha que las dos anteriores, ocupa un tercio de esta estructura Espermateca tubullforme con paredes lisas y conductos espermáticos extremadamente largos; el cuerpo. ligeramente más ancho que los conductos, se continua en un cuello cuyo diámetro es similar al de la cabeza, la cual esta rodeada de una corona de pelos. Este conjunto de caracteres confieren a los eiemplares procedentes de las islas Canarias peculiaridades propia

Impact of High Intensity Interval Training Using Elastic Bands on Glycemic Control in Adults with Type 1 Diabetes: A Pilot Study

[EN] High intensity interval training (HIIT) using elastic bands is easy to do, but no data on its impact on glycemic control in people with type 1 diabetes (T1D) are available. Six males with T1D performed three weekly sessions of HIIT using elastic bands for 12 weeks. Each session consisted of eight exercises. Glycemic control was evaluated by using intermittent scanning continuous glucose monitoring two weeks before study onset (baseline) and during the intervention period in the first two (first stage) and last two weeks (last stage). In the 24 h post-exercise, time-in-range (70-180 mg/dL) was reduced from baseline to the end of the study (67.2% to 63.0%), and time-above-range (>180 mg/dL) seemed to increase from baseline across the study (20.8% -> 27.5% -> 22.1%, from baseline -> first -> last stage), but did not show any statistical significance. Time in hypoglycemia (either < 70 mg/dL or <54 mg/dL) did not show statistically significant differences. This study shows that a HIIT program with elastic bands is safe and effective to perform in T1D patients, keeping blood glucose levels in a safe range.This study was funded by MINECO DPI2016-78831-C2-1-R, Agencia Estatal de Investigacion (PID2019-107722RB-C21/AEI/10.13039/501100011033), FEDER funds from EU, and the Vicerectorate of Research, Innovation and Technology Transference from the Universitat Politecnica de Valencia grant number PAID-06-18. This study was also supported by the official funding agency for biomedical research of the Spanish government, Institute of Health Carlos III (ISCIII) through CIBEROBN CB12/03/30038, and CIBERDEM CB17/08/00004, which is co-funded by the European Regional Development Fund.Martín-San Agustín, R.; Laguna Sanz, AJ.; Bondía Company, J.; Roche, E.; Benítez Martínez, JC.; Ampudia-Blasco, FJ. (2020). Impact of High Intensity Interval Training Using Elastic Bands on Glycemic Control in Adults with Type 1 Diabetes: A Pilot Study. Applied Sciences. 10(19). https://doi.org/10.3390/app10196988101

Epidemiologia del parasitismo intestinal infantil en el valle del Guadalquivir, España

BACKGROUND : Intestinal parasitisms represents a public health problem that should be periodically assessed in each region. In the present paper, a study about prevalence of intestinal parasites, has been carried out in children from the natural region of the Guadalquivir Valley. METHODS: During the period 1994-1996, 1.917 children without symptoms, aging between 6 and 10, were studied by means of coprologycal analysis and Graham method, all of them living in 20 villages in the Guadalquivir valley. RESULTS: The overall prevalence of intestinal parasitisms have been of 27,12%. The reported parasites and their prevalence are as follows: Enterobius vermicularis (20,44%), Giardia lamblia (5,05%), Entamoeba coli (2,45%), Endolimax nana (1,61%), Entamoeba histolytica (0,31%), Entamoeba hartmanni (0,05%), Iodamoeba bütschlii (0,05%). CONCLUSIONS: The overall prevalence of intestinal parasites is similar to that found in other spanish region, if only a little bit more favourable probably due to the long lasting drought and the improvements in health resourses, no geohelmints have been detected unlike other protozoosis, giardiasis mantains a relatively high prevalence.FUNDAMENTO: Las parasitosis intestinales en los niños constituyen un problema de salud pública que debe ser valorado periódicamente en cada región. En este trabajo se aborda, por primera vez en la región natural del Valle del Guadalquivir, un estudio amplio sobre la prevalencia del parasitismo intestinal en la población infantil de la zona. MÉTODOS: Durante el período 1994-1996, mediante análisis coprológico y método de Graham, se ha estudiado a 1.917 niños y niñas asintomáticos, con edades comprendidas entre seis y diez años, residentes en veinte localidades del Valle del Guadalquivir. RESULTADOS: El índice global de parasitación ha sido del 27,12 %. Las especies parásitas detectadas, así como sus prevalencias fueron: Enterobius vermicularis (20,44%), Giardia lamblia (5,05%), Entamoeba coli (2,45%), Endolimax nana (1,61%), Entamoeba histolytica (0,31%), Entamoeba hartmanni (0,05%), Iodamoeba bütschlii (0,05%). CONCLUSIONES: La prevalencia global encontrada es similar a la de otras regiones españolas, aunque quizás pueda considerarse algo más favorable. No se detectan geohelmintos, debido posiblemente a la mejora de la infraestructura higiénico-sanitaria y a los efectos de la prolongada sequía en la zona. La giardiasis, a diferencia de las restantes protozoosis, mantiene una prevalencia relativamente alta

The NALP3/Cryopyrin-Inflammasome Complex is Expressed in LPS-Induced Ocular Inflammation

In the inflammosome complex, NALP3 or NALP1 binds to ASC and activates caspase-1 which induces IL-1β. In murine LPS-induced ocular inflammation, the production of IL-1β is increased. We suggest that NALP3- or NALP1-inflammasome complex can be participating in the LPS-induced ocular inflammation. In this work, eye, brain, testis, heart, spleen, and lung were obtained from C3H/HeN mice treated with LPS for 3 to 48 hours, and the expression of NALP1b, NALP3, ASC, caspase-1, IL-1β, and IL-18 was determined. Infiltrated leukocytes producing IL-1β in the anterior chamber were found at 12-hour posttreatment. A high upregulated expression of NALP3, ASC, caspase-1, IL-1β, and IL-18 was found at the same time when infiltrated leukocytes were observed. NALP1b was not detected in the eye of treated mice. NALP3 was also overexpressed in heart and lung. These results suggest that NALP3-, but not NALP1-inflammosome complex, is participating in the murine LPS-induced ocular inflammation

Study of the near-barrier scattering of 8 He on 208 Pb

The structure and dynamics of 8He have been studied through the collision process with a 208 Pb target at energies of 22 and 16 MeV, above and below the Coulomb barrier, respectively. The energy and angular distributions of the elastically scattered 8He and the 6,4He fragments were measured. In this paper, we discuss the method used to determine the effective position of the beam spot on the reaction target and the scattering and solid angles of each pixel of the detector array.Ministerio de Economía y Competitividad PA2010-22131-C021-01, FPA2014-59954-C3-1-PMinistry of Science and Higher Education of Poland N202 03363European Science Foundation EUI2009-0416

Del contexto cultural al funcionamiento familiar. Conocimientos compartidos y relaciones familiares en adolescentes con intento de suicidio

El objetivo de este texto es identificar y comparar la estructura semántica del dominio cultural, el conocimiento promedio y el grado de consenso cultural sobre las causas del intento de suicidio, los síntomas previos y las estrategias de prevención del intento de suicidio, además evaluar el funcionamiento familiar entre adolescentes mexicanos con y sin intento de suicidio. Se presenta un estudio mixto metodológicamente que usa la técnica de listas libres y el inventario de recursos familiares en una muestra propositiva de 65 adolescentes (13 a 18 años) divididos en dos grupos: el grupo de adolescentes con tentativa suicida y un grupo control con adolescentes estudiantes sin antecedentes de conductas suicidas. Los problemas familiares fueron la principal causa del intento suicida, mientras que la depresión y la tristeza fueron síntomas previos a una tentativa suicida en ambos grupos. La ayuda psicológica y el desarrollo de habilidades de escucha en los padres fueron señaladas como las estrategias para la prevención del suicidio. Respecto del funcionamiento familiar, los adolescentes con tentativa suicida percibieron más conflictos familiares y menor comunicación y apoyo en sus familias en comparación con el grupo control. Los resultados sugieren un conocimiento compartido culturalmente sobre las causas, los síntomas y las estrategias de prevención del intento de suicidio en los adolescentes, el cual se confirma en la percepción del funcionamiento familiar. La familia, elemento central en la cultura mexicana, debe ser considerada en las estrategias de prevención del intento de suicidio en los adolescentes en México. AIM: The aim of the study was to identify and to compare the semantic structure of the cultural domain, the average knowledge and the degree of cultural consensus regarding knowledge of suicide attempts cause, symptoms and prevention strategies to suicide attempt and the family functioning among Mexican adolescents with and without previous suicide attempt. Method: It was a mixed study, using the free-listing technique and an inventory of family resources, with a non-random sample of 65 adolescents (13-18 years) divided in two groups. The suicide attempters group and the control group were high school students, without a history of suicide behaviors. Results: Family problems were identified as the most important cause of suicide attempts in both groups, while depression and sadness were identified as symptoms prior to the suicide attempt in both groups. Psychological aid and development of listening skills in the parents were the most frequent responses regarding prevention strategies to suicide attempt. Regarding family functioning teenage suicide attempters showed more family conflict, less family communication and support than teenage non suicide attempters. Conclusions: The results suggest a same cultural knowledge background regarding causes, symptoms prior and prevention strategies to suicide attempt in Mexican adolescents. Mexican culture centered in family relationships is important to be considered in design of prevention strategies to suicide attempt in adolescence in Mexico.ITESO, A.C