Avaliación do Programa galego de prevención e control da tuberculose 2012-2015. Novas estratexias e indicadores de cara a conseguir a eliminación da tuberculose en Galicia. 2017-2020

Avaliación e prórroga do Programa galego de prevención e control da tuberculose 2012-2015, cuxos obxectivos e estratexias son necesarios adaptar á situación epidemiolóxica actual da tuberculose en Galicia. Os obxectivos propostos están deseñados para conseguirse ao remate do período de vixencia do programa (2017-2020)Evaluación y prórroga del Programa gallego de prevención y control de la tuberculosis 2012-2015, cuyos objetivos y estrategias son necesarios adaptar a la situación epidemiológica actual de la tuberculosis en Galicia. Los objetivos propuestos están diseñados para conseguirse al final del período de vigencia del programa (2017-2020

Application of refrigeration for debittering table olives

During the process of making table olives, it is necessary to remove bitterness caused by phenolic compounds like oleuropein. This debittering effect is achieved by degrading these compounds into non-bitter ones that are beneficial for health due to their antioxidant properties. One of the most used methods is alkaline debittering using NaOH but the main drawback is the environmental impact generated by wastes and degradation of high-value nutraceutical compounds in olives. Different olive debittering pre-treatments followed by refrigeration storage at 5ºC during 90 days have been performed using Ocal variety olives (Olea europaea L.) by combining heat, β- glucosidase and Lactobacillus plantarum treatments. Oleuropein and hydroxytyrosol concentrations were determined in olive pulp and brine. The data has been complemented with sensory tests. The treatment with the best results was storage in refrigeration, which achieved significant debittering and greater degradation of oleuropein, due to the action of endogenous enzymes of the olives

Comparison of the characteristics of tuberculosis cases detected by tuberculosis units by active finding and those declared passively by health professionals. Galicia 2014-2018

Fundamentos: La declaración de enfermedades es una herramienta fundamental en salud pública, imprescindible para conocer la magnitud del problema y poder decidir adecuadamente la manera de resolverlo. La búsqueda activa de casos permite recuperar casos que no fueron registrados mediante la declaración pasiva. En este estudio pretendimos analizar si los casos de tuberculosis (TB) detectados por las Unidades de Tuberculosis (UTB) por búsqueda activa eran equiparables a los declarados de forma pasiva por los profesionales sanitarios o si bien presentaban diferencias. Métodos: Se recogieron los datos del Registro Gallego de Tuberculosis (SITUB), analizando los 2.753 casos de TB detectados entre 2014 y 2018. Se compararon los intervalos de confianza y se analizaron los datos con Ji cuadrado o pruebas T-Student, según fuese requerido. Resultados: El 44,67% de los casos de TB fueron detectados por las UTB mediante búsqueda activa. Se detectó mayor proporción mediante búsqueda activa en bacilíferos, pacientes con cultivo positivo, localización TB pulmonar y alcoholismo, mientras que fue menor en VIH (-) y en casos en edad pediátrica (menores de 15 años). Aunque la proporción del tipo de declaración variaba dependiendo de la UTB o la edad, no se detectaron cambios desagregando por UTB ni al excluir a los menores de 15 años. Conclusiones: De no realizar búsqueda activa, se perderían casi la mitad de los casos. Se observan diferentes características de los pacientes según como hayan sido detectados, aunque no conocemos su posible causa. Por ello, la detección de casos por búsqueda activa es una importante medida de salud pública. Traduci

25 anos de SIDA en Galicia. Novos retos para a Atención Primaria

Desde o ano 1981, no que se describíu o primeiro caso, ata os nosos días, pasaron 25 anos durante os cales se foi establecendo de forma progresiva esta epidemia. A infección polo virus de inmunodeficiencia humana (VIH) foise convertendo nun problema socio-sanitario de primeira orde e nunha das pandemias máis virulentas descritas.Desde el año 1981, en el que se describió el primer caso, hasta nuestros días, pasaron 25 años durante los cuales se fue estableciendo de forma progresiva esta epidemia. La infección por el virus de inmunodeficiencia humana (VIH) se convirtió en un problema socio-sanitario de primer orden y una de las pandemias más virulentas descritas

Plan galego anti VIH/sida e outras infeccións de transmisión sexual (ITS). Prórroga 2019-2022 (novembro 2019)

Este é o documento marco das directrices do control do VIH e as outras ITS para o período indicado en Galicia. Nel detállanse os obxectivos, as actividades e os indicadores.Este es el documento marco de las directrices del control del VIH y otras ITS para el período indicado en Galicia. En él se detallan los objetivos, las actividades y los indicadore

Comorbidities in patients with Primary Sjögren's Syndrome and Systemic Lupus Erythematosus: A comparative registries-based study

OBJECTIVE: To compare the prevalence of the main comorbidities in 2 large cohorts of patients with primary Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE), with a focus on cardiovascular (CV) diseases. METHODS: This was a cross-sectional multicenter study where the prevalence of more relevant comorbidities in 2 cohorts was compared. Patients under followup from SJOGRENSER (Spanish Rheumatology Society Registry of Primary SS) and RELESSER (Spanish Rheumatology Society Registry of SLE), and who fulfilled the 2002 American-European Consensus Group and 1997 American College of Rheumatology classification criteria, respectively, were included. A binomial logistic regression analysis was carried out to explore potential differences, making general adjustments for age, sex, and disease duration and specific adjustments for each variable, including CV risk factors and treatments, when appropriate. RESULTS: A total of 437 primary SS patients (95% female) and 2,926 SLE patients (89% female) were included. The mean age was 58.6 years (interquartile range [IQR] 50.0-69.9 years) for primary SS patients and 45.1 years (IQR 36.4-56.3 years) for SLE patients (P?<?0.001), and disease duration was 10.4 years (IQR 6.0-16.7 years) and 13.0 years (IQR 7.45-19.76 years), respectively (P?<?0.001). Smoking, dyslipidemia, and arterial hypertension were associated less frequently with primary SS (odds ratio [OR] 0.36 [95% confidence interval (95% CI) 0.28-0.48], 0.74 [95% CI 0.58-0.94], and 0.50 [95% CI 0.38-0.66], respectively) as were life-threatening CV events (i.e., stroke or myocardial infarction; OR 0.57 [95% CI 0.35-0.92]). Conversely, lymphoma was associated more frequently with primary SS (OR 4.41 [95% CI 1.35-14.43]). The prevalence of severe infection was lower in primary SS than in SLE (10.1% versus 16.9%; OR 0.54 [95% CI 0.39-0.76]; P?<?0.001). CONCLUSION: Primary SS patients have a consistently less serious CV comorbidity burden and a lower prevalence of severe infection than those with SLE. In contrast, their risk of lymphoma is greater

Comprehensive description of clinical characteristics of a large systemic Lupus Erythematosus Cohort from the Spanish Rheumatology Society Lupus Registry (RELESSER) with emphasis on complete versus incomplete lupus differences

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple organ involvement and pronounced racial and ethnic heterogeneity. The aims of the present work were (1) to describe the cumulative clinical characteristics of those patients included in the Spanish Rheumatology Society SLE Registry (RELESSER), focusing on the differences between patients who fulfilled the 1997 ACR-SLE criteria versus those with less than 4 criteria (hereafter designated as incomplete SLE (iSLE)) and (2) to compare SLE patient characteristics with those documented in other multicentric SLE registries. RELESSER is a multicenter hospital-based registry, with a collection of data from a large, representative sample of adult patients with SLE (1997 ACR criteria) seen at Spanish rheumatology departments. The registry includes demographic data, comprehensive descriptions of clinical manifestations, as well as information about disease activity and severity, cumulative damage, comorbidities, treatments and mortality, using variables with highly standardized definitions. A total of 4.024 SLE patients (91% with ≥4 ACR criteria) were included. Ninety percent were women with a mean age at diagnosis of 35.4 years and a median duration of disease of 11.0 years. As expected, most SLE manifestations were more frequent in SLE patients than in iSLE ones and every one of the ACR criteria was also associated with SLE condition; this was particularly true of malar rash, oral ulcers and renal disorder. The analysis-adjusted by gender, age at diagnosis, and disease duration-revealed that higher disease activity, damage and SLE severity index are associated with SLE [OR: 1.14; 95% CI: 1.08-1.20 (P < 0.001); 1.29; 95% CI: 1.15-1.44 (P < 0.001); and 2.10; 95% CI: 1.83-2.42 (P < 0.001), respectively]. These results support the hypothesis that iSLE behaves as a relative stable and mild disease. SLE patients from the RELESSER register do not appear to differ substantially from other Caucasian populations and although activity [median SELENA-SLEDA: 2 (IQ: 0-4)], damage [median SLICC/ACR/DI: 1 (IQ: 0-2)], and severity [median KATZ index: 2 (IQ: 1-3)] scores were low, 1 of every 4 deaths was due to SLE activity. RELESSER represents the largest European SLE registry established to date, providing comprehensive, reliable and updated information on SLE in the southern European population

Lee, imagina y juega con la literatura infantil y juvenil

Memoria ID-0030. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2014-2015