479 research outputs found
Crude Ambitions: The Internationalization of Emerging National Oil Companies
The burgeoning literature on the internationalization of emerging country NOCs asserts that the combination of technology transfer in the 1970s-80s and sustained high oil prices in the 1990s created an unprecedented opportunity in the 2000s for NOCs to internationalize their operations at a rapid pace, enabling them to compete successfully with International Oil Companies (IOCs) for dominance in global oil markets. The 2000s has indeed witnessed the expansion of emerging country NOCs' investment, exploration, production, and personnel abroad. And yet, this widespread ambition to internationalize has been realized with varying levels of success. We capture this variation by developing an original composite index that assigns NOCs a degree of internationalization score. We then provide an alternative explanation for why emerging country NOCs achieve such different levels of success. Contrary to existing explanations that emphasize structural and economic changes at the international level, we argue that an NOC's capacity to internationalize is constrained by domestic politics; more specifically, the legacy of its mode of emergence, the timing of convergence between the government and NOC management regarding the merits of internationalization, and the sequencing of sectoral reforms vis-à-vis convergence. Ohio State University. Mershon Center for International Security Studies.Event Web Page, photo
Central Asia and the globalisation of the contemporary legal consciousness
What is the logic which governs the processes of legal globalization? How does the transnational proliferation of legal forms operate in the contemporary geo-juridical space? What are the main defining characteristics of the currently dominant mode of transnational legal consciousness and how can the concept of legal consciousness help us understand better the historical ebb and flow of the Western-led projects of good governance promotion in regions like Central Asia after the fall of the Soviet Union? Using Duncan Kennedy’s seminal essay Three Globalizations of Law and Legal Thought as its starting platform, this essay seeks to explore these and a series of other related questions, while also drawing on the work of the Greek Marxist lawyer-philosopher Nicos Poulantzas to help elucidate some latent analytical stress-points in Kennedy’s broader theoretical framework. Reacting against the neo-Orientalist tone adopted across much of the contemporary field of Central Asian studies, it develops an alternative account of the internal history of the legal-globalizational encounter between the Western-based reform entrepreneurs and the national legal-political elites in Central Asia in the post-1991 period, complementing it with a detailed description of the general institutional and discursive structures within which this encounter took place
Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation
Foreign body response (FBR) to biomaterials compromises the function of implants and leads to medical complications. Here, we report a hybrid alginate microcapsule (AlgXO) that attenuated the immune response after implantation, through releasing exosomes derived from human Umbilical Cord Mesenchymal Stem Cells (XOs). Upon release, XOs suppress the local immune microenvironment, where xenotransplantation of rat islets encapsulated in AlgXO led to >170 days euglycemia in immunocompetent mouse model of Type 1 Diabetes. In vitro analyses revealed that XOs suppressed the proliferation of CD3/CD28 activated splenocytes and CD3+ T cells. Comparing suppressive potency of XOs in purified CD3+ T cells versus splenocytes, we found XOs more profoundly suppressed T cells in the splenocytes co-culture, where a heterogenous cell population is present. XOs also suppressed CD3/CD28 activated human peripheral blood mononuclear cells (PBMCs) and reduced their cytokine secretion including IL-2, IL-6, IL-12p70, IL-22, and TNFα. We further demonstrate that XOs mechanism of action is likely mediated via myeloid cells and XOs suppress both murine and human macrophages partly by interfering with NFκB pathway. We propose that through controlled release of XOs, AlgXO provide a promising new platform that could alleviate the local immune response to implantable biomaterials
Mass Calibration and Cosmological Analysis of the SPT-SZ Galaxy Cluster Sample Using Velocity Dispersion and X-ray Measurements
We present a velocity dispersion-based mass calibration of the South Pole
Telescope Sunyaev-Zel'dovich effect survey (SPT-SZ) galaxy cluster sample.
Using a homogeneously selected sample of 100 cluster candidates from 720 deg2
of the survey along with 63 velocity dispersion () and 16 X-ray Yx
measurements of sample clusters, we simultaneously calibrate the
mass-observable relation and constrain cosmological parameters. The
calibrations using and Yx are consistent at the level,
with the calibration preferring ~16% higher masses. We use the full
cluster dataset to measure . The
SPT cluster abundance is lower than preferred by either the WMAP9 or
Planck+WMAP9 polarization (WP) data, but assuming the sum of the neutrino
masses is eV, we find the datasets to be consistent at the
1.0 level for WMAP9 and 1.5 for Planck+WP. Allowing for larger
further reconciles the results. When we combine the cluster and
Planck+WP datasets with BAO and SNIa, the preferred cluster masses are
higher than the Yx calibration and higher than the
calibration. Given the scale of these shifts (~44% and ~23% in mass,
respectively), we execute a goodness of fit test; it reveals no tension,
indicating that the best-fit model provides an adequate description of the
data. Using the multi-probe dataset, we measure and
. Within a CDM model we find eV. We present a consistency test of the cosmic growth rate.
Allowing both the growth index and the dark energy equation of state
parameter to vary, we find and ,
demonstrating that the expansion and the growth histories are consistent with a
LCDM model ().Comment: Accepted by ApJ (v2 is accepted version); 17 pages, 6 figure
Analysis of Sunyaev-Zel'dovich Effect Mass-Observable Relations using South Pole Telescope Observations of an X-ray Selected Sample of Low Mass Galaxy Clusters and Groups
(Abridged) We use 95, 150, and 220GHz observations from the SPT to examine
the SZE signatures of a sample of 46 X-ray selected groups and clusters drawn
from ~6 deg^2 of the XMM-BCS. These systems extend to redshift z=1.02, have
characteristic masses ~3x lower than clusters detected directly in the SPT data
and probe the SZE signal to the lowest X-ray luminosities (>10^42 erg s^-1)
yet.
We develop an analysis tool that combines the SZE information for the full
ensemble of X-ray-selected clusters. Using X-ray luminosity as a mass proxy, we
extract selection-bias corrected constraints on the SZE significance- and
Y_500-mass relations. The SZE significance- mass relation is in good agreement
with an extrapolation of the relation obtained from high mass clusters.
However, the fit to the Y_500-mass relation at low masses, while in good
agreement with the extrapolation from high mass SPT clusters, is in tension at
2.8 sigma with the constraints from the Planck sample. We examine the tension
with the Planck relation, discussing sample differences and biases that could
contribute.
We also present an analysis of the radio galaxy point source population in
this ensemble of X-ray selected systems. We find 18 of our systems have 843 MHz
SUMSS sources within 2 arcmin of the X-ray centre, and three of these are also
detected at significance >4 by SPT. Of these three, two are associated with the
group brightest cluster galaxies, and the third is likely an unassociated
quasar candidate. We examine the impact of these point sources on our SZE
scaling relation analyses and find no evidence of biases. We also examine the
impact of dusty galaxies using constraints from the 220 GHz data. The stacked
sample provides 2.8 significant evidence of dusty galaxy flux, which
would correspond to an average underestimate of the SPT Y_500 signal that is
(17+-9) per cent in this sample of low mass systems.Comment: 15 pages, 7 figure
Probiotic-associated aspiration pneumonia due to Lactobacillus rhamnosus
Lactobacilli are low-virulence, commensal organisms of the gastrointestinal and genitourinary tracts and are commonly used as “probiotic supplements.” Herein, we describe an episode of respiratory syncytial virus (RSV) bronchiolitis with bacterial superinfection secondary to administration of Lactobacillus rhamnosus in an 11-month-old female with trisomy 21
The Redshift Evolution of the Mean Temperature, Pressure, and Entropy Profiles in 80 SPT-Selected Galaxy Clusters
(Abridged) We present the results of an X-ray analysis of 80 galaxy clusters
selected in the 2500 deg^2 South Pole Telescope survey and observed with the
Chandra X-ray Observatory. We divide the full sample into subsamples of ~20
clusters based on redshift and central density, performing an X-ray fit to all
clusters in a subsample simultaneously, assuming self-similarity of the
temperature profile. This approach allows us to constrain the shape of the
temperature profile over 0<r<1.5R500, which would be impossible on a
per-cluster basis, since the observations of individual clusters have, on
average, 2000 X-ray counts. The results presented here represent the first
constraints on the evolution of the average temperature profile from z=0 to
z=1.2. We find that high-z (0.6<z<1.2) clusters are slightly (~40%) cooler both
in the inner (rR500) regions than their low-z
(0.3<z<0.6) counterparts. Combining the average temperature profile with
measured gas density profiles from our earlier work, we infer the average
pressure and entropy profiles for each subsample. Overall, our observed
pressure profiles agree well with earlier lower-redshift measurements,
suggesting minimal redshift evolution in the pressure profile outside of the
core. We find no measurable redshift evolution in the entropy profile at
rR500 in
our high-z subsample. This flattening is consistent with a temperature bias due
to the enhanced (~3x) rate at which group-mass (~2 keV) halos, which would go
undetected at our survey depth, are accreting onto the cluster at z~1. This
work demonstrates a powerful method for inferring spatially-resolved cluster
properties in the case where individual cluster signal-to-noise is low, but the
number of observed clusters is high.Comment: 17 pages, 13 figures, submitted to ApJ. Updated following referee
repor
Constraints on the CMB Temperature Evolution using Multi-Band Measurements of the Sunyaev Zel'dovich Effect with the South Pole Telescope
The adiabatic evolution of the temperature of the cosmic microwave background
(CMB) is a key prediction of standard cosmology. We study deviations from the
expected adiabatic evolution of the CMB temperature of the form using measurements of the spectrum of the Sunyaev
Zel'dovich Effect with the South Pole Telescope (SPT). We present a method for
using the ratio of the Sunyaev Zel'dovich signal measured at 95 and 150 GHz in
the SPT data to constrain the temperature of the CMB. We demonstrate that this
approach provides unbiased results using mock observations of clusters from a
new set of hydrodynamical simulations. We apply this method to a sample of 158
SPT-selected clusters, spanning the redshift range , and
measure , consistent with the standard model
prediction of . In combination with other published results, we
constrain , an improvement of over
published constraints. This measurement also provides a strong constraint on
the effective equation of state in models of decaying dark energy
.Comment: Submitted to MNRAS Letter
Cosmological Constraints from Galaxy Clusters in the 2500 square-degree SPT-SZ Survey
(abridged) We present cosmological constraints obtained from galaxy clusters
identified by their Sunyaev-Zel'dovich effect signature in the 2500 square
degree South Pole Telescope Sunyaev Zel'dovich survey. We consider the 377
cluster candidates identified at z>0.25 with a detection significance greater
than five, corresponding to the 95% purity threshold for the survey. We compute
constraints on cosmological models using the measured cluster abundance as a
function of mass and redshift. We include additional constraints from
multi-wavelength observations, including Chandra X-ray data for 82 clusters and
a weak lensing-based prior on the normalization of the mass-observable scaling
relations. Assuming a LCDM cosmology, where the species-summed neutrino mass
has the minimum allowed value (mnu = 0.06 eV) from neutrino oscillation
experiments, we combine the cluster data with a prior on H0 and find sigma_8 =
0.797+-0.031 and Omega_m = 0.289+-0.042, with the parameter combination
sigma_8(Omega_m/0.27)^0.3 = 0.784+-0.039. These results are in good agreement
with constraints from the CMB from SPT, WMAP, and Planck, as well as with
constraints from other cluster datasets. Adding mnu as a free parameter, we
find mnu = 0.14+-0.08 eV when combining the SPT cluster data with Planck CMB
data and BAO data, consistent with the minimum allowed value. Finally, we
consider a cosmology where mnu and N_eff are fixed to the LCDM values, but the
dark energy equation of state parameter w is free. Using the SPT cluster data
in combination with an H0 prior, we measure w = -1.28+-0.31, a constraint
consistent with the LCDM cosmological model and derived from the combination of
growth of structure and geometry. When combined with primarily geometrical
constraints from Planck CMB, H0, BAO and SNe, adding the SPT cluster data
improves the w constraint from the geometrical data alone by 14%, to w =
-1.023+-0.042
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