On the optical--infra-red continuum emission from equatorial discs of supergiant B[e] stars

Two models of the circumstellar disc around supergiant B[e] stars are discussed: an equatorial wind model produced by wind bi-stability, and a Keplerian viscous disc model. Both models are successful in providing a site for dust formation once they have cooled sufficiently. However, the optical--infra-red continuum is calculated and it is found that both models have significant trouble in accounting for observations. In particular the optical--near-IR emission is accounted for, but the dust emission is underestimated by at least an order of magnitude. Variations in the structure of the models (the temperature variation with radius, the density structure and the dust opacity) are investigated to assess how (in)appropriate the standard models are for supergiant B[e] star discs. Changing the temperature structure, and making simple dust opacity changes within the disc has little effect on the resultant continuum emission. By altering the density structure of the discs, the continuum may be accounted for by both models: the equatorial wind model requires a very flat density profile which is impossible to explain with any accelerating wind, and the viscous disc model's density structure is required to fall off less steeply with radius than would have been expected, although this may be explained from consideration of viscous processes in the disc. It is recognised that both theoretical interpretations have difficulties and unsolved problems.Comment: 9 pages, 6 figures, accepted by Astronomy and Astrophysic

Case Study #8-7 of the Program: ''Food Policy For Developing Countries: The Role Of Government In The Global Food System''

13 pp.©Cornell University, Ithaca, New York. All rights reserved. This case study may be reproduced for educational purposes without express permission but must include acknowledgment to Cornell University. No commercial use is permitted without permission.Soil salinity is one of the critical factors responsible for the ongoing land degradation in the irrigated lowlands of Central Asia, including in the lower reaches of the Amudarya Delta. This land degradation hinders sustainable development and presents a major challenge for the area's rural population, whose livelihood security depends on irrigated agriculture. The factors causing soil salinity are multifaceted and interlinked; recent studies and interventions confirm that no one action alone will deliver a sustainable solution. Recommendations for alleviating soil salinity should take into account the complex interactions and can be formulated only once the interlinked factors causing soil salinity are understood. In the past, little attention was paid to creeping land degradation, which has resulted from soil salinization and waterlogging across huge agricultural and even nonagricultural areas. This case study focuses on the vicious circle of soil salinization: agriculture's consumption of large amounts of water contributes to shallow groundwater, leading to recurring soil salinity, which in turn demands more water for leaching (flushing the salts out of the rooting zone). The situation is exacerbated when water is not available in sufficient amounts in time and in space. The seemingly stable present water flows in the major water source (the Amudarya River) since the major drought in 2000–01 is caused by increased glacier melting in upstream countries. This water supply in turn diverts attention from the strong need for improved irrigation and cropping practices. Efforts aimed at reducing the amounts of irrigation water use face the problem of the devilish vicious circle, which has not only technical but also financial and political dimensions. Your assignment is to present policy options for managing soil salinity in a more sustainable way. Focus on incentives and instruments to solve the artificial water shortage problem.Cornell University Division of Nutritional Science

The role of virtual water for sustainable economic restructuring: Evidence from Uzbekistan, Central Asia

Increases in water demand due to population growth, industrial development and urbanization necessitate economically efficient use of water resources worldwide. This is particularly true in the dryland zones of the world relying on irrigated agriculture for economic development such as in Uzbekistan, Central Asia. Due to ill-managed water resources and the dominance of high water intensive crops, water use efficiency in the region is very low. This challenges Uzbekistan to modernize its agricultural sectors and develop its industrial sectors guided by the principles of a green economy, which are the basis for sustainable growth. Therefore, this study aims to prioritize economic sectors according to their sustainable growth potential. To this end, we employ a national inputoutput model to estimate economic backward and forward linkage measures and virtual water contents across the sectors. Our results indicate that developing agro-processing industries and the livestock sector rather than relying on the production of raw agricultural commodities such as cotton, wheat, and rice provides more sustainable economic development in Uzbekistan. However, to exploit these comparative advantages, the necessary market infrastructure and institutions as well as an increased control over wastewaters would need to be implemented

The role of virtual water for sustainable economic restructuring : evidence from Uzbekistan, Central Asia

Increases in water demand due to population growth, industrial development and urbanization necessitate economically efficient use of water resources worldwide. This is particularly true in the dryland zones of the world relying on irrigated agriculture for economic development such as in Uzbekistan, Central Asia. Due to ill-managed water resources and the dominance of high water intensive crops, water use efficiency in the region is very low. This challenges Uzbekistan to modernize its agricultural sectors and develop its industrial sectors guided by the principles of a "green economy", which are the basis for sustainable growth. Therefore, this study aims to prioritize economic sectors according to their sustainable growth potential. To this end, we employ a national input-output model to estimate economic backward and forward linkage measures and virtual water contents across the sectors. Our results indicate that developing agro-processing industries and the livestock sector rather than relying on the production of raw agricultural commodities such as cotton, wheat, and rice provides more sustainable economic development in Uzbekistan. However, to exploit these comparative advantages, the necessary market infrastructure and institutions as well as an increased control over wastewaters would need to be implemented

Scope and constraints for tree planting in the irrigated landscapes of the Aral Sea Basin: case studies in Khorezm Region, Uzbekistan

A wealth of research papers, reports, and newsprint demonstrate the wide international interest in the ecological deterioration in the Aral Sea Basin in Central Asia (CA). The demise of the Aral Sea is a symptom that results from intensive agricultural activities aiming at maximizing agricultural production while neglecting environmental sustainability, as exemplified by the land use patterns also prevalent in the Republic of Uzbekistan, one of the five newly established states in CA. The environmental degradation is acute and continues, since various factors conducive to it have not been eradicated. This discussion paper deals with the potential role of forestry-based production systems and in their contribution to counterbalancing the ecological landscape demise in the region. This discussion paper starts with a brief overview of environmental conditions in CA, followed by a discussion of forestry and agroforestry in CA's irrigated semi-arid and arid landscapes. The paper focuses on Uzbekistan, and more specifically the province (viloyat) of Khorezm, which is located at the southern rim of the Aral Sea Basin and serves as an example for the Middle Asia lowlands. The results of surveys on farmers' perception of forest and tree products, as well as the outcomes of field measurements of the productivity of tree stands and agroforestry systems, regional forestry governance, and the market situation for timber products are discussed. Following data mining of secondary sources, field, market and household surveys, combined with in-depth analyses using remote sensing techniques, the paper re-assesses the tree resources of Uzbekistan and concludes that the present use and management of trees and forests is inadequate. Well-designed multi-species windbreaks are absent (single-tree rows of mulberry comprise about 50% of the present tree strips), only 70% of the tree windbreaks were oriented in the North-South and North/West-South/East directions, from which the highest wind speeds (>3 m s-1) are generally measured, and the majority of the investigated tree strips did not satisfy the minimal height of 5 m. More than half (55%) of the strips did not stretch over the entire length of the related field. However, other structural criteria such as stand porosity and width had acceptable values. In the hedgerow systems monitored tree planting schemes varied considerably but on average were much lower compared to the recommended planting schemes by forestry administrations as the perennial crops were of more importance to the farmers. The farmers planted mostly fruit trees to increase income and improve their food basket, but none of the ca. 100 interviewed was ecologically motivated. However, the total land area of the various surveyed agroforestry systems on both private and rented land was the largest where tree age did not exceed 12 years, thus indicating the interest of tree planting. The surveys results are followed by a review of forestry policies in Uzbekistan. The paper concludes with a set of recommendations concerning managerial and research needs for forest and agroforestry systems in irrigated drylands of CA, and outlines the opportunities and need for external support at both the country and sub-regional level. Despite the role trees could potentially play, the lack of training of the farming population, reduced capacities of the forestry administration and their staff as well as shortcomings in the forest legislation have resulted in many underperforming "goodwill" efforts. Due to the complexity of the social, economical and physical components and their interdependencies, this paper calls for integrated knowledge generation, concerted action and for administrative and research support. The crisis in the Aral Sea Basin has a strong global dimension, which calls for targeted support at both country and international donor community levels

The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase

<p>Abstract</p> <p>Background</p> <p>Soluble guanylate cyclases generate cyclic GMP when bound to nitric oxide, thereby linking nitric oxide levels to the control of processes such as vascular homeostasis and neurotransmission. The guanylate cyclase catalytic module, for which no structure has been determined at present, is a class III nucleotide cyclase domain that is also found in mammalian membrane-bound guanylate and adenylate cyclases.</p> <p>Results</p> <p>We have determined the crystal structure of the catalytic domain of a soluble guanylate cyclase from the green algae <it>Chlamydomonas reinhardtii </it>at 2.55 Å resolution, and show that it is a dimeric molecule.</p> <p>Conclusion</p> <p>Comparison of the structure of the guanylate cyclase domain with the known structures of adenylate cyclases confirms the close similarity in architecture between these two enzymes, as expected from their sequence similarity. The comparison also suggests that the crystallized guanylate cyclase is in an inactive conformation, and the structure provides indications as to how activation might occur. We demonstrate that the two active sites in the dimer exhibit positive cooperativity, with a Hill coefficient of ~1.5. Positive cooperativity has also been observed in the homodimeric mammalian membrane-bound guanylate cyclases. The structure described here provides a reliable model for functional analysis of mammalian guanylate cyclases, which are closely related in sequence.</p

Scope and constraints for tree planting in the irrigated landscapes of the Aral Sea Basin : case studies in Khorezm Region, Uzbekistan

A wealth of research papers, reports, and newsprint demonstrate the wide international interest in the ecological deterioration in the Aral Sea Basin in Central Asia (CA). The demise of the Aral Sea is a symptom that results from intensive agricultural activities aiming at maximizing agricultural production while neglecting environmental sustainability, as exemplified by the land use patterns also prevalent in the Republic of Uzbekistan, one of the five newly established states in CA. The environmental degradation is acute and continues, since various factors conducive to it have not been eradicated. This discussion paper deals with the potential role of forestry-based production systems and in their contribution to counterbalancing the ecological landscape demise in the region. This discussion paper starts with a brief overview of environmental conditions in CA, followed by a discussion of forestry and agroforestry in CA’s irrigated semi-arid and arid landscapes. The paper focuses on Uzbekistan, and more specifically the province (viloyat) of Khorezm, which is located at the southern rim of the Aral Sea Basin and serves as an example for the Middle Asia lowlands. The results of surveys on farmers’ perception of forest and tree products, as well as the outcomes of field measurements of the productivity of tree stands and agroforestry systems, regional forestry governance, and the market situation for timber products are discussed. Following data mining of secondary sources, field, market and household surveys, combined with in-depth analyses using remote sensing techniques, the paper re-assesses the tree resources of Uzbekistan and concludes that the present use and management of trees and forests is inadequate. Well-designed multi-species windbreaks are absent (single-tree rows of mulberry comprise about 50% of the present tree strips), only 70% of the tree windbreaks were oriented in the North-South and North/West-South/East directions, from which the highest wind speeds (>3 m s -1) are generally measured, and the majority of the investigated tree strips did not satisfy the minimal height of 5 m. More than half (55%) of the strips did not stretch over the entire length of the related field. However, other structural criteria such as stand porosity and width had acceptable values. In the hedgerow systems monitored tree planting schemes varied considerably but on average were much lower compared to the recommended planting schemes by forestry administrations as the perennial crops were of more importance to the farmers. The farmers planted mostly fruit trees to increase income and improve their food basket, but none of the ca. 100 interviewed was ecologically motivated. However, the total land area of the various surveyed agroforestry systems on both private and rented land was the largest where tree age did not exceed 12 years, thus indicating the interest of tree planting. The surveys results are followed by a review of forestry policies in Uzbekistan. The paper concludes with a set of recommendations concerning managerial and research needs for forest and agroforestry systems in irrigated drylands of CA, and outlines the opportunities and need for external support at both the country and sub-regional level. Despite the role trees could potentially play, the lack of training of the farming population, reduced capacities of the forestry administration and their staff as well as shortcomings in the forest legislation have resulted in many underperforming “goodwill” efforts. Due to the complexity of the social, economical and physical components and their interdependencies, this paper calls for integrated knowledge generation, concerted action and for administrative and research support. The crisis in the Aral Sea Basin has a strong global dimension, which calls for targeted support at both country and international donor community levels

Production and characterization of miro- and nano-features in biomedical alumina and zirconia ceramics using a tape casting route

A process of micromolding, delivering micro- and nanopatterned ceramic surfaces for biomaterial applications is described in this work. To create the desired structures, tape casting of ceramic slurries on microfabricated silicon mold was used. Several tape casting slurry compositions were tested to evaluate the feasibility of transferring micro- and nano-features from silicon molds. Used ceramics were alumina (α-Al2O3) and yttria stabilized zirconia. Three types of polymeric binders for the green tape (PVB, PES, and PVP) were investigated using three different solvents (ethanol, n-methyl-pyrrolidone, water). Well-defined features in shapes of wells with diameters down to 2.4 μm and a depth of 10 μm and pillars with diameters down to 1.7 μm and a height of 3 μm were obtained. Morphology, grain size and porosity of the sintered bodies were characterized. Finally fibroblast cells were cultured on the surfaces in order to observe their morphology under influence of the microstructured surfaces

A structural role for the PHP domain in E. coli DNA polymerase III.

RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.BACKGROUND: In addition to the core catalytic machinery, bacterial replicative DNA polymerases contain a Polymerase and Histidinol Phosphatase (PHP) domain whose function is not entirely understood. The PHP domains of some bacterial replicases are active metal-dependent nucleases that may play a role in proofreading. In E. coli DNA polymerase III, however, the PHP domain has lost several metal-coordinating residues and is likely to be catalytically inactive. RESULTS: Genomic searches show that the loss of metal-coordinating residues in polymerase PHP domains is likely to have coevolved with the presence of a separate proofreading exonuclease that works with the polymerase. Although the E. coli Pol III PHP domain has lost metal-coordinating residues, the structure of the domain has been conserved to a remarkable degree when compared to that of metal-binding PHP domains. This is demonstrated by our ability to restore metal binding with only three point mutations, as confirmed by the metal-bound crystal structure of this mutant determined at 2.9 Å resolution. We also show that Pol III, a large multi-domain protein, unfolds cooperatively and that mutations in the degenerate metal-binding site of the PHP domain decrease the overall stability of Pol III and reduce its activity. CONCLUSIONS: While the presence of a PHP domain in replicative bacterial polymerases is strictly conserved, its ability to coordinate metals and to perform proofreading exonuclease activity is not, suggesting additional non-enzymatic roles for the domain. Our results show that the PHP domain is a major structural element in Pol III and its integrity modulates both the stability and activity of the polymerase