Dietary exposure to DDT: hormonal and antifertility effects in the rat.

Dept. of Biological Sciences. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1972 .C42. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1972

Reaching Traditional and Nontraditional Extension Audiences

Two diverse extension audiences in Polk County, North Carolina, were sent a mailed questionnaire to determine their levels of use of extension information and their preferred means for receiving extension information

Trust And Energy-Aware Routing Protocol for Wireless Sensor Networks Based on Secure Routing

Wireless Sensor Network (WSN) is a network area that includes a large number of nodes and the ability of wireless transmission. WSNs are frequently employed for vital applications in which security and dependability are of utmost concern. The main objective of the proposed method is to design a WSN to maximize network longevity while minimizing power usage. In a WSN, trust management is employed to encourage node collaboration, which is crucial for achieving dependable transmission. In this research, a novel Trust and Energy Aware Routing Protocol (TEARP) in wireless sensors networks is proposed, which use blockchain technology to maintain the identity of the Sensor Nodes (SNs) and Aggregator Nodes (ANs). The proposed TEARP technique provides a thorough trust value for nodes based on their direct trust values and the filtering mechanisms generate the indirect trust values. Further, an enhanced threshold technique is employed to identify the most appropriate clustering heads based on dynamic changes in the extensive trust values and residual energy of the networks. Lastly, cluster heads should be routed in a secure manner using a Sand Cat Swarm Optimization Algorithm (SCSOA). The proposed method has been evaluated using specific parameters such as Network Lifetime, Residual Energy, Throughpu,t Packet Delivery Ratio, and Detection Accuracy respectively. The proposed TEARP method improves the network lifetime by 39.64%, 33.05%, and 27.16%, compared with Energy-efficient and Secure Routing (ESR), Multi-Objective nature-inspired algorithm based on Shuffled frog-leaping algorithm and Firefly Algorithm (MOSFA) , and Optimal Support Vector Machine (OSVM)

A general few-projection method for tomographic reconstruction of samples consisting of several distinct materials

We present a method for tomographic reconstruction of objects containing several distinct materials, which is capable of accurately reconstructing a sample from vastly fewer angular projections than required by conventional algorithms. The algorithm is more general than many previous discrete tomography methods, as: (i) a priori knowledge of the exact number of materials is not required; (ii) the linear attenuation coefficient of each constituent material may assume a small range of a priori unknown values. We present reconstructions from an experimental x-ray computed tomography scan of cortical bone acquired at the SPring-8 synchrotron

A matched-pair cluster design study protocol to evaluate implementation of the Canadian C-spine rule in hospital emergency departments: Phase III

BACKGROUND: Physicians in Canadian emergency departments (EDs) annually treat 185,000 alert and stable trauma victims who are at risk for cervical spine (C-spine) injury. However, only 0.9% of these patients have suffered a cervical spine fracture. Current use of radiography is not efficient. The Canadian C-Spine Rule is designed to allow physicians to be more selective and accurate in ordering C-spine radiography, and to rapidly clear the C-spine without the need for radiography in many patients. The goal of this phase III study is to evaluate the effectiveness of an active strategy to implement the Canadian C-Spine Rule into physician practice. Specific objectives are to: 1) determine clinical impact, 2) determine sustainability, 3) evaluate performance, and 4) conduct an economic evaluation. METHODS: We propose a matched-pair cluster design study that compares outcomes during three consecutive 12-months "before," "after," and "decay" periods at six pairs of "intervention" and "control" sites. These 12 hospital ED sites will be stratified as "teaching" or "community" hospitals, matched according to baseline C-spine radiography ordering rates, and then allocated within each pair to either intervention or control groups. During the "after" period at the intervention sites, simple and inexpensive strategies will be employed to actively implement the Canadian C-Spine Rule. The following outcomes will be assessed: 1) measures of clinical impact, 2) performance of the Canadian C-Spine Rule, and 3) economic measures. During the 12-month "decay" period, implementation strategies will continue, allowing us to evaluate the sustainability of the effect. We estimate a sample size of 4,800 patients in each period in order to have adequate power to evaluate the main outcomes. DISCUSSION: Phase I successfully derived the Canadian C-Spine Rule and phase II confirmed the accuracy and safety of the rule, hence, the potential for physicians to improve care. What remains unknown is the actual change in clinical behaviors that can be affected by implementation of the Canadian C-Spine Rule, and whether implementation can be achieved with simple and inexpensive measures. We believe that the Canadian C-Spine Rule has the potential to significantly reduce health care costs and improve the efficiency of patient flow in busy Canadian EDs

The Freshman, vol. 5, no. 10

The Freshman was a weekly, student newsletter issued on Mondays throughout the academic year. The newsletter included calendar notices, coverage of campus social events, lectures, and athletic teams. The intent of the publication was to create unity, a sense of community, and class spirit among first year students

The Freshman, vol. 5, no. 13

The Freshman was a weekly, student newsletter issued on Mondays throughout the academic year. The newsletter included calendar notices, coverage of campus social events, lectures, and athletic teams. The intent of the publication was to create unity, a sense of community, and class spirit among first year students

The Freshman, vol. 5, no. 14

The Freshman was a weekly, student newsletter issued on Mondays throughout the academic year. The newsletter included calendar notices, coverage of campus social events, lectures, and athletic teams. The intent of the publication was to create unity, a sense of community, and class spirit among first year students

A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency

N-Glycanase 1 (NGLY1) is a cytoplasmic deglycosylating enzyme. Loss-of-function mutations in the NGLY1 gene cause NGLY1 deficiency, which is characterized by developmental delay, seizures, and a lack of sweat and tears. To model the phenotypic variability observed among patients, we crossed a Drosophila model of NGLY1 deficiency onto a panel of genetically diverse strains. The resulting progeny showed a phenotypic spectrum from 0 to 100% lethality. Association analysis on the lethality phenotype, as well as an evolutionary rate covariation analysis, generated lists of modifying genes, providing insight into NGLY1 function and disease. The top association hit was Ncc69 (human NKCC1/2), a conserved ion transporter. Analyses in NGLY1-/- mouse cells demonstrated that NKCC1 has an altered average molecular weight and reduced function. The misregulation of this ion transporter may explain the observed defects in secretory epithelium function in NGLY1 deficiency patients