A Note on Estimating the Cost of Capital for the Undiversified Business Owner

About 70 percent of businesses are organized as sole proprietorships, and many business owners are not well-diversified, yet the finance discipline is largely silent regarding how to estimate the opportunity cost of capital for undiversified investors. In this paper, the Capital Market Line (CML) is presented as the appropriate vehicle for estimating such an investor’s return requirement. Recognizing the applicability of the CML allows the undiversified investor’s exposure to an investment’s total risk to be objectively linked to the market price of risk. Knowing the appropriate return requirement is useful for valuation and capital budgeting purposes

Soil conditioners

1 online resource (PDF, 4 pages)This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu

A Pilot Randomized Clinical Trial of a Teamwork Intervention for Heart Failure Care Dyads

Background: Dyadic heart failure (HF) management can improve outcomes for patients and caregivers and can be enhanced through eHealth interventions. Objective: To evaluate the feasibility, acceptability, and preliminary efficacy of an eHealth dyadic teamwork intervention, compared to an attention control condition. Methods: We recruited 29 HF patient-caregiver dyads from inpatient units and randomized dyads to an intervention or a control group. We calculated enrollment and retention rates, described acceptability using interview and questionnaire data, and computed intervention effect sizes. Results: 37% of eligible dyads agreed to participate and 93% of randomized participants completed follow-up questionnaires. Participants found both study conditions to be acceptable. Between-group effect sizes suggested that the intervention led to improvements in relationship quality, self-efficacy, and quality of life for patients and caregivers. Conclusions: Dyadic recruitment from acute care settings is challenging. Findings provide initial evidence that our intervention can contribute to better health outcomes for HF dyads

Mineralogical characterization of protolith and fault rocks from the SAFOD Main Hole

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94865/1/grl22060.pd

A transient positive association between direct-acting antiviral therapy for hepatitis C infection and drug-related hospitalization among people who inject drugs: self-controlled case-series analysis of national data

Background and Aims: Direct-acting antiviral (DAA) treatment has an established positive effect on liver outcomes in people with hepatitis C infection; however, there is insufficient evidence regarding its effects on the 'extra-hepatic' outcomes of drug-related hospitalization and mortality (DRM) among people who inject drugs (PWID). We investigated associations between these outcomes and DAA treatment by comparing post-treatment to baseline periods using a within-subjects design to minimize selection bias concerns with cohort or case-control designs.Design: This was a self-controlled case-series study.Setting: Scotland, 1 January 2015-30 November 2020.Participants: The study population of non-cirrhotic, DAA-treated PWID was identified using a data set linking Scotland's hepatitis C diagnosis, HCV clinical databases, national inpatient/day-case hospital records and the national deaths register. Three principal outcomes (drug overdose admission, non-viral injecting related admission and drug-related mortality) were defined using ICD codes.Measurements: Self-controlled case-series methodology was used to estimate the relative incidence (RI) of each outcome associated with time on treatment and up to six 90-day exposure risk periods thereafter.Findings: A total of 6050 PWID were treated with DAAs in the sampling time-frame. Compared with the baseline period, there was a significantly lowered risk of a drug overdose hospital admission in the second to fifth exposure risk periods only [relative incidence (RI) = 0.86, 95% confidence interval (CI) = 0.80-0.99; 0.89, 95% CI = 0.80-0.99; 0.86, 95% CI = 0.77-0.96; 0.88, 95% CI = 0.78-0.99, respectively]. For non-viral injecting-related admission, there was a reduced risk in the first, third and fourth exposure risk periods (RI = 0.76, 95% CI = 0.64-0.90; 0.75, 95% CI = 0.62-0.90; 0.79, 95% CI = 0.66-0.96, respectively). There was no evidence for reduced DRM risk in any period following treatment end.Conclusions: Among people who inject drugs in Scotland, direct-acting antiviral treatment appears to be associated with a small, non-durable reduction in the risk of drug-related hospital admission, but not drug-related mortality. Direct-acting antiviral therapy, despite high effectiveness against liver disease, does not appear to offer a panacea for reducing other drug-related health harms.</p

High-Potency Cannabis, Mental Health and Substance Use in Adolescence:Results from a UK General Population Sample

Importance Cannabis use is consistently linked to poorer mental health outcomes, and there is evidence that use of higher-potency cannabis increases these risks. To date, no studies have described the association between cannabis potency and concurrent mental health in a general population sample or addressed confounding using longitudinal data. Objective To explore the association between cannabis potency and substance use and mental health outcomes, accounting for preceding mental health and frequency of cannabis use. Design, Setting, and Participants This cohort study used data from the Avon Longitudinal Study of Parents and Children, a UK birth cohort of participants born between April 1, 1991, and December 31, 1992. Present data on outcomes and exposures were collected between June 2015 and October 2017 from 1087 participants at 24 years of age who reported recent cannabis use. Exposures Self-reported type of cannabis most commonly used in the past year, coded to a binary exposure of use of high-potency cannabis or lower-potency cannabis. Main Outcomes and Measures Outcomes were reported frequency of cannabis use, reported cannabis use problems, recent use of other illicit drugs, tobacco dependence, alcohol use disorder, depression, generalized anxiety disorder, and psychotic-like experiences. The study used secondary data; consequently, the hypotheses were formulated after data collection. Results Past-year cannabis use was reported by 1087 participants (580 women; mean [SD] age at onset of cannabis use, 16.7 [3.0] years). Of these, 141 participants (13.0%) reported the use of high-potency cannabis. Use of high-potency cannabis was associated with increased frequency of cannabis use (adjusted odds ratio [AOR], 4.38; 95% CI, 2.89-6.63), cannabis problems (AOR, 4.08; 95% CI, 1.41-11.81), and increased likelihood of anxiety disorder (AOR, 1.92; 95% CI, 1.11-3.32). Adjustment for frequency of cannabis use attenuated the association with psychotic experiences (AOR 1.29; 95% CI, 0.67-2.50), tobacco dependence (AOR, 1.42; 95% CI, 0.89-2.27), and other illicit drug use (AOR, 1.29; 95% CI, 0.77-2.17). There was no evidence of association between the use of high-potency cannabis and alcohol use disorder or depression. Conclusions and Relevance To our knowledge, this study provides the first general population evidence suggesting that the use of high-potency cannabis is associated with mental health and addiction. Limiting the availability of high-potency cannabis may be associated with a reduction in the number of individuals who develop cannabis use disorders, the prevention of cannabis use from escalating to a regular behavior, and a reduction in the risk of mental health disorders

The Claims Culture: A Taxonomy of Industry Attitudes

This paper presents an analysis of a familiar aspect of construction industry culture that we have dubbed 'the claims culture'. This is a culture of contract administration that lays a strong emphasis on the planning and management of claims. The principal elements of the analysis are two sets of distinctions. The first comprises economic and occupational orders, referring to two kinds of control that are exercised over the construction process; predicated respectively on economic ownership and occupational competence. The second refers to contrasting attitudes towards relationships and problem solving within these orders: respectively 'distributive' and 'integrative'. The concepts of economic and occupational order entail further sub-categories. The various attitudes associated with these categories and sub-categories are described. They are assessed as to their consequences for change initiatives in the industry

Historical vegetation of central southwest Oregon, based on GLO survey notes : final report to USDI Bureau of Land Management, Medford District

Final report to USDI Bureau of Land Management. Medford District, Oregon.Historical vegetation at the time of European settlement is of great interest to both the public and land managers, but is poorly documented. One source of data are the earliest land survey records of the General Land Office (GLO). Rectangular township surveys in Southwest Oregon were initiated in the mid 1850’s as settlers began to claim homesteads in the Bear Creek Valley surrounding what is now Medford. We examined GLO land survey field notes and plats (maps) accompanying the surveys, transcribed GLO landscape data into an Access database, and classified the data set into very general vegetation types for mapping. About 89 vegetation types (subclasses) were described for mapping historic vegetation, distinguished by major differences in plant composition and topographic features. Tree density was estimated from section line descriptions and witness tree spacing at corners, and was used to classify stands into tree classes. These types then were combined into broad “Vegetation Classes” for mapping (i.e. savanna, shrubland, forest, prairie). Classifying and mapping historical vegetation occurred on about 418,500 acres in an earlier OSU study, and about 720,700 acres in this BLM study, located in Jackson and Josephine Counties. The authors merged results from these adjacent GLO studies, expanding the coverage to approximately 1.14 million acres (49 townships). Modern soil surveys of the study area helped the authors interpret GLO data and draw vegetation boundaries. About 44% of the landscape was closed upland forest, 41% woodland, 1.4% riparian forest, 2% oak or conifer savanna, 1% shrublands, and 11% bottomland meadow or upland prairie. Forest types ranged from moist, mixed conifer uplands to dry valley ponderosa pine-hardwood grassland. Large areas of prairie and mixed oak-conifer woodland dominated many low elevation locations on plains, foothills, and especially clayey terraces or southern slopes near what is now Medford. Nearly 115 plant species or plant groups were identified by the surveyors, mostly trees and shrubs. Some were misidentified and not easily interpreted by the authors when archaic names were used by the surveyors. Grazing quality was frequently noted as surveyors attempted to describe land productivity for livestock. Historic baseline plant data is presented for broad landscape transects and sometimes by topographic positions, but is limited by the sketchy nature of the original surveyor notes. Nearly 350 homestead parcels of various sizes were claimed in the study, as identified in GLO survey notes and on Donation Land Claim maps, showing how quickly settlement occurred in the study area after gold was discovered in 1851. Most early homesteads included prairie or oak savanna, which was open and more easily converted to farmland or pasture. Early saw mills, grist mills, fields, roads, water diversions and major Indian trails were also identified and transcribed from the GLO records

A Geologic Play Book for Utica Shale Appalachian Basin Exploration

This “Geologic Play Book for Utica Shale Appalachian Basin Exploration” (hereafter referred to as the “Utica Shale Play Book Study” or simply “Study”) represents the results of a two-year research effort by workers in five different states with the financial support of fifteen oil and gas industry partners. The Study was made possible through a coordinated effort between the Appalachian Basin Oil & Natural Gas Research Consortium (AONGRC) and the West Virginia University Shale Research, Education, Policy and Economic Development Center