601 research outputs found
How Hertzian solitary waves interact with boundaries in a 1-D granular medium
We perform measurements, numerical simulations, and quantitative comparisons
with available theory on solitary wave propagation in a linear chain of beads
without static preconstrain. By designing a nonintrusive force sensor to
measure the impulse as it propagates along the chain, we study the solitary
wave reflection at a wall. We show that the main features of solitary wave
reflection depend on wall mechanical properties. Since previous studies on
solitary waves have been performed at walls without these considerations, our
experiment provides a more reliable tool to characterize solitary wave
propagation. We find, for the first time, precise quantitative agreements.Comment: Proof corrections, ReVTeX, 11 pages, 3 eps (Focus and related papers
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Experimental evidence of solitary wave interaction in Hertzian chains
We study experimentally the interaction between two solitary waves that
approach one to another in a linear chain of spheres interacting via the Hertz
potential. When these counter propagating waves collide, they cross each other
and a phase shift respect to the noninteracting waves is introduced, as a
result of the nonlinear interaction potential. This observation is well
reproduced by our numerical simulations and it is shown to be independent of
viscoelastic dissipation at the beads contact. In addition, when the collision
of equal amplitude and synchronized counter propagating waves takes place, we
observe that two secondary solitary waves emerge from the interacting region.
The amplitude of secondary solitary waves is proportional to the amplitude of
incident waves. However, secondary solitary waves are stronger when the
collision occurs at the middle contact in chains with even number of beads.
Although numerical simulations correctly predict the existence of these waves,
experiments show that their respective amplitude are significantly larger than
predicted. We attribute this discrepancy to the rolling friction at the beads
contacts during solitary wave propagation
Intrinsic Energy Localization through Discrete Gap Breathers in One-Dimensional Diatomic Granular Crystals
We present a systematic study of the existence and stability of discrete
breathers that are spatially localized in the bulk of a one-dimensional chain
of compressed elastic beads that interact via Hertzian contact. The chain is
diatomic, consisting of a periodic arrangement of heavy and light spherical
particles. We examine two families of discrete gap breathers: (1) an unstable
discrete gap breather that is centered on a heavy particle and characterized by
a symmetric spatial energy profile and (2) a potentially stable discrete gap
breather that is centered on a light particle and is characterized by an
asymmetric spatial energy profile. We investigate their existence, structure,
and stability throughout the band gap of the linear spectrum and classify them
into four regimes: a regime near the lower optical band edge of the linear
spectrum, a moderately discrete regime, a strongly discrete regime that lies
deep within the band gap of the linearized version of the system, and a regime
near the upper acoustic band edge. We contrast discrete breathers in anharmonic
FPU-type diatomic chains with those in diatomic granular crystals, which have a
tensionless interaction potential between adjacent particles, and highlight in
that the asymmetric nature of the latter interaction potential may lead to a
form of hybrid bulk-surface localized solutions
Development of Population Tariffs for the CarerQol Instrument for Hungary, Poland and Slovenia
__Background:__ The CarerQol instrument can be used in economic evaluations to measure the care-related quality of life of informal caregivers. Tariff sets are available for Australia, Germany, Sweden, the Netherlands, the UK, and the USA.
__Objective:__ Our objective was to develop tariff sets for the CarerQol instrument for Hungary, Poland and Slovenia and to compare these with the existing value sets.
__Methods:__ Discrete-choice experiments were carried out in Hungary, Poland and Slovenia. Data were collected through an online survey between November 2018 and January 2019, using representative samples of 1000 respondents per country. Tariffs were calculated from coefficient estimates from panel mixed multinomial logit models with random parameters.
__Results:__ All seven CarerQol domains contributed significantly to the utility associated with different caregiving situations. Attributes valued highest were ‘physical health
A bibliography of parasites and diseases of marine and freshwater fishes of India
With the increasing demand for fish as human food, aquaculture both in freshwater
and salt water is rapidly developing over the world. In the developing countries,
fishes are being raised as food. In many countries fish farming is a very important
economic activity. The most recent branch, mariculture, has shown advances in
raising fishes in brackish, estuarine and bay waters, in which marine, anadromous and
catadromous fishes have successfully been grown and maintained
Metabolic Adaptation in Transplastomic Plants Massively Accumulating Recombinant Proteins
BACKGROUND: Recombinant chloroplasts are endowed with an astonishing capacity to accumulate foreign proteins. However, knowledge about the impact on resident proteins of such high levels of recombinant protein accumulation is lacking. METHODOLOGY/PRINCIPAL FINDINGS: Here we used proteomics to characterize tobacco (Nicotiana tabacum) plastid transformants massively accumulating a p-hydroxyphenyl pyruvate dioxygenase (HPPD) or a green fluorescent protein (GFP). While under the conditions used no obvious modifications in plant phenotype could be observed, these proteins accumulated to even higher levels than ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco), the most abundant protein on the planet. This accumulation occurred at the expense of a limited number of leaf proteins including Rubisco. In particular, enzymes involved in CO(2) metabolism such as nuclear-encoded plastidial Calvin cycle enzymes and mitochondrial glycine decarboxylase were found to adjust their accumulation level to these novel physiological conditions. CONCLUSIONS/SIGNIFICANCE: The results document how protein synthetic capacity is limited in plant cells. They may provide new avenues to evaluate possible bottlenecks in recombinant protein technology and to maintain plant fitness in future studies aiming at producing recombinant proteins of interest through chloroplast transformation
Normative resistance to responsibility to protect in times of emerging multipolarity: the cases of Brazil and Russia
This article assesses the normative resistance to Responsibility to Protect adopted by Brazil and Russia against the backdrop of their international identities and self-assigned roles in a changing global order. Drawing upon the framework of Bloomsfield's norm dynamics role spectrum, it argues that while the ambiguous Russian role regarding this principle represents an example of 'norm antipreneurship', particularities of Brazil's resistance are better grasped by a new category left unaccounted for by this model, which this study portrays as 'contesting entrepreneur'.- (undefined
Cap-Gly Proteins at Microtubule Plus Ends: Is EB1 Detyrosination Involved?
Localization of CAP-Gly proteins such as CLIP170 at microtubule+ends results from their dual interaction with α-tubulin and EB1 through their C-terminal amino acids −EEY. Detyrosination (cleavage of the terminal tyrosine) of α-tubulin by tubulin-carboxypeptidase abolishes CLIP170 binding. Can detyrosination affect EB1 and thus regulate the presence of CLIP170 at microtubule+ends as well? We developed specific antibodies to discriminate tyrosinated vs detyrosinated forms of EB1 and detected only tyrosinated EB1 in fibroblasts, astrocytes, and total brain tissue. Over-expressed EB1 was not detyrosinated in cells and chimeric EB1 with the eight C-terminal amino acids of α-tubulin was only barely detyrosinated. Our results indicate that detyrosination regulates CLIPs interaction with α-tubulin, but not with EB1. They highlight the specificity of carboxypeptidase toward tubulin
Post-Modification of the Electronic Properties by Addition of π-Stacking Additives in N-Heterocyclic Carbene Complexes with Extended Polyaromatic Systems
A series of iridium complexes containing phenanthro[4,5-abc]phenazino[11,12-d]imidazol-2-ylidene and acetonaphtho[1,2-b]quinoxaline[11,12-d]imidazol-2-ylidene ligands have been obtained and fully characterized. These complexes display highly extended polyaromatic systems attached to the backbone of the N-heterocyclic carbene. The presence of this extended polyaromatic system makes the electron-donating character of these ligands sensitive to the presence of π-stacking additives, such as pyrene and hexafluorobenzene. The computational studies predict that the addition of pyrene affords an increase of the electron-donating character of the polyaromatic ligand (TEP decreases), while the addition of hexafluorobenzene has the opposite effect (TEP increases). This prediction is experimentally corroborated by IR spectroscopy, by measuring the shift of the CO stretching bands of a series of IrCl(NHC)(CO)2 complexes, where NHC is the N-heterocyclic carbene ligand with the polyaromatic system. Finally, the energy of the π-stacking interaction of one of the key Ir(I) complexes with pyrene and hexafluorobenzene has been estimated by using the Benesi-Hildebrand treat-ment, based on the δ-shifts observed by 1H NMR spectroscopy.MEC of Spain (CTQ2011-24055/BQU
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