Impacto dos choques macroeconômicos sobre o setor industrial cearense: uma abordagem utilizando o modelo de vetor de correção de erro

Esse artigo tem como objetivo investigar como o setor industrial do Ceará responde aos choques que ocorrem em importantes variáveis macroeconômicas e examina uma possível relação de equilíbrio de longo prazo entre as variáveis e o produto industrial. Para isto, foi utilizado um conjunto de dados mensais, entre janeiro de 2002 a dezembro de 2019, das variáveis Preços do Petróleo, Taxa de Câmbio, Taxa de Juros e Produção Industrial. A estratégia metodológica se concentrou na análise da relação de equilíbrio de longo prazo entre as variáveis e na estimação de uma função impulso resposta e decomposição da variância, por meio de uma modelagem com Vetores Autoregressivos VAR/VEC. Como resultados, foi possível identificar a existência de uma relação de longo prazo entre o produto industrial e as variáveis do sistema

O efeito de aposentadorias, pensões e programas sociais na frequência escolar e oferta de trabalho dos jovens brasileiros

A pesquisa analisou o impacto de aposentadorias/pensões e programas sociais sobre a frequência escolar e oferta de trabalho dos jovens de 15 a 21 anos de idade. Dos resultados encontrados, verificou-se que em domicílios em que residem aposentados e/ou pensionistas há uma redução na oferta de trabalho e aumento da frequência escolar dos jovens nas áreas urbanas. Concluiu-se que o impacto de programas sociais, tanto na zona urbana, como no meio rural, aumenta as chances de os jovens estudarem e trabalharem, sendo que o efeito médio sobre aqueles jovens “nem-nem” é menor.This research analyses the impact of pensions and social programs school attendance and supply in the labor market of young people aged 15 to 21 years. It was verified in households where retirees and/or pensioners live a reduction in the labor supply and an increase in school attendance of young people in urban areas. It was concluded that the impact of social programs, both in urban and rural areas, increases the chances of young people studying and working, and the average effect on those young people who are neither working nor studying (NEET) is smaller

Mecanismo de transmissão de preços: uma análise sobre as exportações brasileiras de melão

As condições ambientais consentiram ao Brasil o posto de grande produtor de frutas tropicais. Este artigo verifica a transmissão de preços do melão entre o Brasil, Estados Unidos e União Europeia, entre 2003 a 2013. A partir da análise de dados de séries temporais, a relação entre os preços baseou-se em estimações de um modelo vetorial autorregressivo (VAR) e também no teste de causalidade de Granger, respectivamente. Os resultados mostram que os preços do mercado interno não sofrem influência dos demais e influenciam o mercado da União Europeia, exercendo cada vez mais impacto nas oscilações do mercado internacional afetando expectativas de produção e comercialização dos produtores.Environmental conditions consented to Brazil, since the major producer of tropical fruits. This article verifies the transmission melon prices, with Brazil, US market and the European Union from 2003 to 2013. Using time series data, the relationship between the prices was analyzed by estimates from a vector autoregression model (VAR) and the Granger causality test respectively. The results shows that the domestic prices are not influenced from others and influence the EU market, exerting more and more impact on the fluctuations of the international market affecting production expectations and marketing of producers

LASER TERAPÊUTICO DE BAIXA INTENSIDADE NA OTIMIZAÇÃO E PERFORMANCE DO MOVIMENTO HUMANO

A laserterapia de baixa intensidade (LLLT) a aplicao de luz (usualmente um laser de baixa potncia na faixa de 1 a 500 mW) com finalidade teraputica, pois parece agir no metabolismo energtico da clula, estimulando efeitos fotoqumicos e fotofsicos na mitocndria e potencializando a funo mitocondrial aumenta-se o consumo de oxignio e incrementa-se a sntese de ATP. Este artigo tem como objetivo descrever como o laser teraputico tem sido atualmente utilizado de maneira complementar ao treinamento para otimizar o movimento e performance humana. Foi realizada uma pesquisa utilizando as bases de dados Medline, Scielo, BIREME, LILACS e diretrio CAPES utilizando-se os descritores: exerccio, performance, laser e seus correspondentes em ingls, publicados de 2002 at maio de 2012. Foram selecionados para discusso 7 artigos que atendiam os critrios de incluso. O laser teraputico de baixa intensidade tem sido empregado com frequncia e h resultados que inferem melhora na performance quando utilizado antes da prtica da atividade fsica e efeitos na recuperao muscular aps atividade, no entanto o maior desafio das pesquisas definir os parmetros ideais para uso do laser. Palavras-chave: exerccio, performance, laser

Chiral bistacrine analogues : synthesis, cholinesterase inhibitory activity and a molecular modeling approach

Cholinesterase enzymes are important targets for the therapy of Alzheimer’s disease. Tacrine-based dual binding site cholinesterases inhibitors are potential disease-modifying anti-Alzheimer drug candidates. In the present work, we described the synthesis of a series of chiral homo- and heterodimers of bis(7)-tacrine connected by a heptylene chain as a spacer with the methyl substituent at the C-3 position of the alicyclic region of tacrine nucleus and/or a chlorine atom attached to the C-6. Friedländer cyclocondensation between (R) or (S) 3-methylcyclohexanone prepared from monoterpene pulegone and o-aminobenzoic acids in the presence of POCl3 afford 9-chloroacridines as intermediates, which were used to the synthesis of homo- and heterodimers. All compounds demonstrated to be potent inhibitors of acetylcholinesterase (AChE) at low nanomolar concentration and showed selectivity for AChE over butyrylcholinesterase (BuChE). Furthermore, the affinity difference between enantiomeric bis(7)-tacrine analogues series indicated some degree of stereoselectivity in the active site of AChE for chiral bis-cognitin compounds

A Fatal Bacteremia Caused by Hypermucousviscous KPC-2 Producing Extensively Drug-Resistant K64-ST11 Klebsiella pneumoniae in Brazil

We report a fatal bacteremia caused by Klebsiella pneumoniae in a 60–70-year-old patient from Brazil. The genomic analysis of three isolates (from blood culture, nasal and anal swabs) showed that the bacteremia was caused by a KPC-2 producing extensively drug-resistant K64-ST11 hypermucousviscous K. pneumoniae (hmKP) harboring several virulence and antimicrobial resistance genes. Although the isolates did not present virulence markers associated with hypervirulent K. pneumoniae (hvKP), they showed invasion and toxicity to epithelial Hep-2 cells; resistance to cell microbicidal mechanisms; and blood and human serum survival, evidencing their pathogenic potential. This study highlights the risk of infection caused by hmKp strains not characterized as hvKP as well as the clinical implications and difficulty of treatment, especially in elderly or immunocompromised patients

MAMMALS IN PORTUGAL : A data set of terrestrial, volant, and marine mammal occurrences in P ortugal

Mammals are threatened worldwide, with 26% of all species being includedin the IUCN threatened categories. This overall pattern is primarily associatedwith habitat loss or degradation, and human persecution for terrestrial mam-mals, and pollution, open net fishing, climate change, and prey depletion formarine mammals. Mammals play a key role in maintaining ecosystems func-tionality and resilience, and therefore information on their distribution is cru-cial to delineate and support conservation actions. MAMMALS INPORTUGAL is a publicly available data set compiling unpublishedgeoreferenced occurrence records of 92 terrestrial, volant, and marine mam-mals in mainland Portugal and archipelagos of the Azores and Madeira thatincludes 105,026 data entries between 1873 and 2021 (72% of the data occur-ring in 2000 and 2021). The methods used to collect the data were: live obser-vations/captures (43%), sign surveys (35%), camera trapping (16%),bioacoustics surveys (4%) and radiotracking, and inquiries that represent lessthan 1% of the records. The data set includes 13 types of records: (1) burrowsjsoil moundsjtunnel, (2) capture, (3) colony, (4) dead animaljhairjskullsjjaws, (5) genetic confirmation, (6) inquiries, (7) observation of live animal (8),observation in shelters, (9) photo trappingjvideo, (10) predators dietjpelletsjpine cones/nuts, (11) scatjtrackjditch, (12) telemetry and (13) vocalizationjecholocation. The spatial uncertainty of most records ranges between 0 and100 m (76%). Rodentia (n=31,573) has the highest number of records followedby Chiroptera (n=18,857), Carnivora (n=18,594), Lagomorpha (n=17,496),Cetartiodactyla (n=11,568) and Eulipotyphla (n=7008). The data setincludes records of species classified by the IUCN as threatened(e.g.,Oryctolagus cuniculus[n=12,159],Monachus monachus[n=1,512],andLynx pardinus[n=197]). We believe that this data set may stimulate thepublication of other European countries data sets that would certainly contrib-ute to ecology and conservation-related research, and therefore assisting onthe development of more accurate and tailored conservation managementstrategies for each species. There are no copyright restrictions; please cite thisdata paper when the data are used in publications.info:eu-repo/semantics/publishedVersio

IL-17 Produced during Trypanosoma cruzi Infection Plays a Central Role in Regulating Parasite-Induced Myocarditis

Chagas disease is caused by the intracellular parasite Trypanosoma cruzi. This infection has been considered one of the most neglected diseases and affects several million people in the Central and South America. Around 30% of the infected patients develop digestive and cardiac forms of the disease. Most patients are diagnosed during the chronic phase, when the treatment is not effective. Here, we showed by the first time that IL-17 is produced during experimental T. cruzi infection and that it plays a significant role in host defense, modulating parasite-induced myocarditis. Applying this analysis to humans could be of great value in unraveling the elements involved in the pathogenesis of chagasic cardiopathy and could be used in the development of alternative therapies to reduce morbidity during the chronic phase of the disease, as well as clinical markers of disease progression. The understanding of these aspects of disease may be helpful in reducing the disability-adjusted life years (DALYs) and costs to the public health service in developing countries

Lidar Observations in South America. Part I - Mesosphere and Stratosphere

South America covers a large area of the globe and plays a fundamental function in its climate change, geographical features, and natural resources. However, it still is a developing area, and natural resource management and energy production are far from a sustainable framework, impacting the air quality of the area and needs much improvement in monitoring. There are significant activities regarding laser remote sensing of the atmosphere at different levels for different purposes. Among these activities, we can mention the mesospheric probing of sodium measurements and stratospheric monitoring of ozone, and the study of wind and gravity waves. Some of these activities are long-lasting and count on the support from the Latin American Lidar Network (LALINET). We intend to pinpoint the most significant scientific achievements and show the potential of carrying out remote sensing activities in the continent and show its correlations with other earth science connections and synergies. In Part I of this chapter, we will present an overview and significant results of lidar observations in the mesosphere and stratosphere. Part II will be dedicated to tropospheric observations